Gene Information

Name : murD (PA14_57370)
Accession : YP_792760.1
Strain : Pseudomonas aeruginosa UCBPP-PA14
Genome accession: NC_008463
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 5110888 - 5112234 bp
Length : 1347 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAGCCTGATCGCCTCCGACCACTTCCGCATCGTTGTCGGCCTCGGCAAGAGCGGCATGTCCCTGGTGCGCTACCTGGC
GCGCCGCGGCTTGCCTTTCGCCGTGGTCGATACCCGAGAGAACCCGCCGGAGCTGGCCACCCTGCGTGCCCAGTATCCGC
AGGTGGAAGTGCGTTGCGGCGAACTCGACGCCGAGTTCCTCTGCTCCGCCCGCGAACTCTACGTCAGCCCCGGCTTGTCG
CTGCGCACCCCTGCGCTGGTACAGGCCGCCGCGAAAGGCGTGCGCATCTCCGGTGACATCGATCTCTTCGCCCGCGAGGC
GAAGGCACCGATCGTCGCCATCACCGGTTCCAACGCGAAGAGCACCGTGACCACCCTGGTGGGCGAAATGGCGGTGGCCG
CGGACAAGCGTGTCGCCGTCGGCGGCAACCTCGGCACCCCGGCGCTCGACCTGCTGGCCGACGACATCGAGCTGTACGTG
CTGGAGCTGTCGAGCTTCCAGCTGGAAACCTGCGATCGCCTCAACGCCGAGGTGGCGACCGTGCTGAACGTCAGCGAAGA
CCATATGGATCGCTACGACGGCATGGCTGACTACCACCTGGCCAAGCACCGGATCTTCCGCGGTGCCCGCCAGGTCGTGG
TGAATCGCGCCGATGCCCTGACCCGACCGCTGATCGCCGATACCGTGCCGTGCTGGTCGTTCGACCTGAACAAGCCGGAC
TTCAAGGCTTTCGGCCTGATCGAGGAAGACGGCCAGAAGTGGCTGGCGTTCCAGTTCGACAAGCTGCTGCCGGTCGGCGA
ACTGAAGATCCGTGGCGCCCACAACTATTCCAACGCGCTCGCCGCGCTGGCGCTGGGCCATGCGGTCGGCCTGCCGTTCG
ACGCCATGCTCGGCGCGCTGAAGGCGTTTTCCGGCCTGGCTCATCGCTGCCAGTGGGTACGCGAGCGGCAGGGCGTGAGC
TACTACGACGATTCCAAGGCCACCAACGTCGGCGCCGCCCTGGCGGCGATCGAGGGGCTGGGTGCCGACATCGACGGCAA
GCTGGTGCTGCTCGCCGGCGGAGACGGCAAGGGCGCCGATTTCCATGACCTGCGCGAGCCGGTCGCGCGCTTCTGCCGGG
CGGTGGTACTGCTTGGCCGTGACGCCGGGCTGATTGCCCAGGCACTGGGCAACGCGGTACCGCTGGTGCGCGTCGCAACG
CTGGACGAAGCAGTCCGGCAGGCCGCCGAGCTGGCCCGCGAAGGCGATGCGGTGCTGTTGTCGCCGGCCTGCGCGAGCCT
GGACATGTTCAAGAACTTCGAAGAACGCGGACGCCTGTTCGCCAAAGCCGTAGAGGAGCTAGCGTGA

Protein sequence :
MSLIASDHFRIVVGLGKSGMSLVRYLARRGLPFAVVDTRENPPELATLRAQYPQVEVRCGELDAEFLCSARELYVSPGLS
LRTPALVQAAAKGVRISGDIDLFAREAKAPIVAITGSNAKSTVTTLVGEMAVAADKRVAVGGNLGTPALDLLADDIELYV
LELSSFQLETCDRLNAEVATVLNVSEDHMDRYDGMADYHLAKHRIFRGARQVVVNRADALTRPLIADTVPCWSFDLNKPD
FKAFGLIEEDGQKWLAFQFDKLLPVGELKIRGAHNYSNALAALALGHAVGLPFDAMLGALKAFSGLAHRCQWVRERQGVS
YYDDSKATNVGAALAAIEGLGADIDGKLVLLAGGDGKGADFHDLREPVARFCRAVVLLGRDAGLIAQALGNAVPLVRVAT
LDEAVRQAAELAREGDAVLLSPACASLDMFKNFEERGRLFAKAVEELA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 5e-94 54
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 5e-94 54