Gene Information

Name : exaC (PA14_38840)
Accession : YP_791255.1
Strain : Pseudomonas aeruginosa UCBPP-PA14
Genome accession: NC_008463
Putative virulence/resistance : Virulence
Product : NAD+ dependent acetaldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 3462683 - 3464203 bp
Length : 1521 bp
Strand : -
Note : -

DNA sequence :
ATGATCTACGCAGCGCCCGGAACCCCCGGTGCCGTCGTCACCTTCAAGCCTCGCTACGGCAACTACATCGGCGGCGAGTT
CGTGCCTCCGGTCAAGGGCCAGTACTTCACCAACACCTCGCCGGTGAACGGCCAGCCGATCGCCGAGTTCCCCCGTTCCA
CCGCCGAGGACATCGACAAGGCCCTCGACGCCGCCCACGCCGCCGCCGACGCCTGGGGCCGTACCTCGGTGCAGGAGCGT
TCGAACATCCTGCTGAAGATCGCCGACCGCATCGAGCAGAACCTGGAACTGCTCGCCGTCACCGAGACCTGGGACAACGG
CAAGGCCGTGCGCGAGACCCTCAACGCCGACATTCCCCTGGCCGCCGACCACTTCCGCTACTTCGCCGGCTGCATCCGCG
CCCAGGAAGGCTCCGCCGCCGAGATCAACGACAGCACCGTGGCCTACCACATCCATGAGCCGCTGGGCGTGGTCGGGCAG
ATCATCCCGTGGAACTTCCCGCTGCTGATGGCCGCCTGGAAGCTGGCCCCGGCGCTGGCCGCCGGCAACTGCGTGGTGCT
CAAGCCGGCCGAGCAGACCCCGCTGGGCATCTGCGTGCTGCTGGAACTCATCGGCGACCTGCTGCCGCCGGGCGTGCTCA
ACGTCGTCCAGGGCTTCGGCAGGGAGGCCGGCGAGGCCCTGGCCACCAGCAAGCGCATCGCCAAGATCGCCTTCACCGGT
TCCACCCCGGTCGGCTCGCACATCCTCAAGTGCGCGGCGGAGAACATCATTCCCTCCACCGTCGAGCTGGGCGGCAAGAG
CCCGAACATCTATTTCGAAGACATCATGCAGGCCGAGCCGGCGTTCATCGAGAAGGCCGCCGAGGGCCTGGTGCTGGCTT
TCTTCAACCAGGGCGAGGTGTGCACCTGCCCGTCCCGCGCGCTGGTCCAGGAGTCGATCTACCCGGCGTTCATGGAAGAG
GTGCTGAAGAAGGTCAGGGCGATCAAGCGCGGCGACCCGCTGGACACCGAGACCATGGTCGGCGCCCAGGCTTCCCAGCA
GCAGTACGAGAAGATCCTCTCCTACCTCGACATCGCCCAGCAGGAAGGCGCCGAAGTGCTCACCGGCGGCAGCGTCGAGA
AGCTCGAAGGCAACCTGGCCAGCGGCTACTACATCCAGCCGACCCTGCTCAAGGGACACAACAAGATGCGCGTGTTCCAG
GAGGAAATCTTCGGCCCGGTGGTCGGCGTCACCACCTTCAAGGACGAAGCCGAGGCCCTGGCCATCGCCAACGACACCGA
GTACGGCCTCGGCGCCGGCCTCTGGACCCGCGACATCAACCGCGCCTACCGCATGGGCCGCGGGATCAAGGCCGGTCGCG
TGTGGACCAACTGCTACCACCTGTACCCGGCCCACGCCGCGTTCGGCGGCTACAAGAAGTCCGGCGTCGGTCGCGAGACG
CACAAGATGATGCTTGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACGACATCGACCCGCTGGGCTTCTTCTG
A

Protein sequence :
MIYAAPGTPGAVVTFKPRYGNYIGGEFVPPVKGQYFTNTSPVNGQPIAEFPRSTAEDIDKALDAAHAAADAWGRTSVQER
SNILLKIADRIEQNLELLAVTETWDNGKAVRETLNADIPLAADHFRYFAGCIRAQEGSAAEINDSTVAYHIHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLGICVLLELIGDLLPPGVLNVVQGFGREAGEALATSKRIAKIAFTG
STPVGSHILKCAAENIIPSTVELGGKSPNIYFEDIMQAEPAFIEKAAEGLVLAFFNQGEVCTCPSRALVQESIYPAFMEE
VLKKVRAIKRGDPLDTETMVGAQASQQQYEKILSYLDIAQQEGAEVLTGGSVEKLEGNLASGYYIQPTLLKGHNKMRVFQ
EEIFGPVVGVTTFKDEAEALAIANDTEYGLGAGLWTRDINRAYRMGRGIKAGRVWTNCYHLYPAHAAFGGYKKSGVGRET
HKMMLDHYQQTKNLLVSYDIDPLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-149 67
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-157 66
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-157 66
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-157 66
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-156 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
exaC YP_791255.1 NAD+ dependent acetaldehyde dehydrogenase VFG0082 Protein 2e-149 67