Gene Information

Name : kdsB (PA14_25530)
Accession : YP_790194.1
Strain : Pseudomonas aeruginosa UCBPP-PA14
Genome accession: NC_008463
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2230872 - 2231636 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGACCCAGGCGTTCACTGTCGTCATTCCCGCCCGCTACGCCTCCACTCGTCTGCCCGGCAAGCCATTGCAGGATATCGC
CGGCCAGCCAATGATCCAGCGCGTCTGGAACCAGGCCCGCAAGAGCGCCGCCAGCCGCGTGGTCGTCGCCACCGACGACG
AACGCATCCTGGCGGCGTGCCAGGGGTTCGGCGCCGAGGCGCTGCTGACGCGTGCCGAGCACAACTCCGGCACCGATCGC
CTGGAGGAAGTCGCTTCCCGGCTCGGCCTGGCCAGCGATGCCATCGTGGTCAACGTCCAGGGCGACGAACCGCTGATCCC
CCCGGCGCTCATCGACCAGGTGGCGGCCAACCTGGCGGCGCACCCGGAAGCCGCCATCGCTACCCTGGCCGAGCCGATCC
ATGAGGTCTCCGCGCTGTTCAATCCGAACGTGGTCAAGGTCGCCACCGACATCGACGGCCTGGCCCTGACTTTCAGTCGT
GCGCCCTTGCCCTGGGCTCGCGACGCCTTCGCCCGCGATCGCGACAGCCTGCCGGAGGGCGTGCCCTATCGTCGCCACAT
CGGCATCTACGCCTATCGCGTGGGTTTCCTTGCCGATTTCGTCGCCTGGGGACCGTGCTGGCTGGAGAACGCCGAAAGCC
TCGAGCAATTGCGCGCGCTCTGGCACGGGGTGCGAATCCATGTGGCCGATGCCCGCGAAACCATGCTTCCGGGCGTGGAT
ACGCCGGAAGACCTCGAACGCGTTCGCCGCGTGCTGGGGGACTGA

Protein sequence : 
MTQAFTVVIPARYASTRLPGKPLQDIAGQPMIQRVWNQARKSAASRVVVATDDERILAACQGFGAEALLTRAEHNSGTDR
LEEVASRLGLASDAIVVNVQGDEPLIPPALIDQVAANLAAHPEAAIATLAEPIHEVSALFNPNVVKVATDIDGLALTFSR
APLPWARDAFARDRDSLPEGVPYRRHIGIYAYRVGFLADFVAWGPCWLENAESLEQLRALWHGVRIHVADARETMLPGVD
TPEDLERVRRVLGD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-36 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-36 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 5e-36 43