Gene Information

Name : Bamb_1689 (Bamb_1689)
Accession : YP_773580.1
Strain :
Genome accession: NC_008390
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1869078 - 1870694 bp
Length : 1617 bp
Strand : -
Note : TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: bsu:BG11020 2,3-dihydroxybenzoate-AMP ligase (enterobactin synthetase component E)

DNA sequence : 
ATGACGTCCGCGAAATGCACGCCGTGGCCGGACGCGTTCGCCGAGGCGTATCGGCAGAAGGGGTACTGGCTCGGCCAGTC
GTTCGCGCAATGGTTCGACGAACGCGTCGCGCGGCACGCCGAACGCGTCGCGCTCGTACAGGGCGACCTGCGCTGGTCGT
ACCGGACGTTCGCGGCGGAAGCCGAGCGCACGGCCCGTGCGTTGACCGCGTGCGGGATCGTGCCGGGCGAGCGCGTCGTC
GTGCAGTTGCCGAACTGCGTCGCTTTCTTCGCGGTGACGTTCGCGCTGTTCCGGATCGGCGCACTGCCGGTGTTTGCGCT
GCCCGCGCATCGCCGGCGCGAGATCGGCTACTTTTGCCGGCACGCGGGCGCGGTCGCCTATGTCGCGGCGGAACGGCACG
ACGGGTTCGACTACAGGGCGCTCGCGAGCGAGATCCGCGCCGACGCGCCGACGCTGCGCCACATGCTGTTCACCGCGCCC
GGCAATACGCGCGTCGCACTGCCGGAGCCGACGCCCGACGTCGCGCTGCCGCCGGGGCCCGGCGCGCACGAGGTCGCGTT
CCTGCAACTGTCGGGTGGCAGCACGGGTACGCCAAAGCTGATCCCGCGCACGCACGACGACTATCTGTACAGCGTGCGCG
AGAGCGCGCGCATTTGCGGGCTGACCGAGCGCAGCGTCTATCTCGCGGCGCTGCCGGCCGCGCATAACTATGCGCTGAGT
TCGCCGGGTTCGCTCGGCGTCTTCGATGCCGGCGGCACCGTCGTGCTGAGCGACGGCGCGAGCCCTGATGCCGCGTTCCC
GCTGATCGAGCGCGAGCGCGTGACAGTGGCGGCACTGGTGCCGCCACTCGTGCCCGTGTGGTTGGCAGCGGCCGGGCAGC
GGCGCGGCGCGCTCGCGAGCCTCGAACTCGTGCAGGTCGGCGGCGCGCGCTTCGATCCGGCGCTCGCGGCCCGCGCGGCC
GACGGCTTCGGCGCGCAATTGCAGCAGGTGTTCGGGATGGCCGAAGGGCTCGTCAACTACACGCGGCTCGACGATCCGCG
CGACGTGGTGATCGCCACGCAGGGGCGCCCGATCTCGCCGGACGACGAGGTCCGCATCGTCGACGACGACGACCGCCCGG
TCGCACCCGGTGAGGTCGGCCATCTGCTGACGCGCGGCCCGTACACGATCCGCGGCTACTACGACGCAGCCGCGCACAAC
GCGCGCGCGTTCACGGCGGACGGCTTCTATCGCACCGGCGATCGCGTCCGCCTGACGGCGGGCGGCCAGATCGTCGTCGA
GGGGCGCGCGAAAGACCAGATCAACCGCGGCGGCGAGAAGATCCCGGCCGAGGAGATCGAACACCTGCTGCTCGCGCATC
CGGGTGTCGTCGACGCGGCGCTGGTCGCGATGCCCGACCCGTATCTCGGCGAACGCAGTTGTGCGTACGTGATTCGCGGC
GTGCCGGCGCCGGCCGCGGCGGATCTCGTGCGCTTCGTGCGTGAGCAGGGCGTGGCGGCGTACAAGGTGCCCGACCGGAT
CGAATTCGTCGACGCATTCCCGAAAACGCCGGTCGGCAAGATCGACAAGCGCGCGCTTCGACAGCACATCGCGGATCGGC
TCGCCGCCGCCGCTTGA

Protein sequence : 
MTSAKCTPWPDAFAEAYRQKGYWLGQSFAQWFDERVARHAERVALVQGDLRWSYRTFAAEAERTARALTACGIVPGERVV
VQLPNCVAFFAVTFALFRIGALPVFALPAHRRREIGYFCRHAGAVAYVAAERHDGFDYRALASEIRADAPTLRHMLFTAP
GNTRVALPEPTPDVALPPGPGAHEVAFLQLSGGSTGTPKLIPRTHDDYLYSVRESARICGLTERSVYLAALPAAHNYALS
SPGSLGVFDAGGTVVLSDGASPDAAFPLIERERVTVAALVPPLVPVWLAAAGQRRGALASLELVQVGGARFDPALAARAA
DGFGAQLQQVFGMAEGLVNYTRLDDPRDVVIATQGRPISPDDEVRIVDDDDRPVAPGEVGHLLTRGPYTIRGYYDAAAHN
ARAFTADGFYRTGDRVRLTAGGQIVVEGRAKDQINRGGEKIPAEEIEHLLLAHPGVVDAALVAMPDPYLGERSCAYVIRG
VPAPAAADLVRFVREQGVAAYKVPDRIEFVDAFPKTPVGKIDKRALRQHIADRLAAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-82 48
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-82 48
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-82 48
ybtE CAA21394.1 - Virulence HPI Protein 3e-82 48
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-82 48
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-82 48
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-82 48
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 8e-82 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-81 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bamb_1689 YP_773580.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-106 55
Bamb_1689 YP_773580.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 9e-97 51
Bamb_1689 YP_773580.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 9e-85 45