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Name : clpB (FTH_0089) Accession : YP_762773.1 Strain : Francisella tularensis OSU18 Genome accession: NC_008369 Putative virulence/resistance : Virulence Product : endopeptidase Clp Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : 3.4.21.92 Position : 89015 - 91594 bp Length : 2580 bp Strand : - Note : caseinolytic protease DNA sequence : ATGGATATAAATAAATTTACAATAAAACTACAAGAAGCTCTAGCTGAGGCTCAATCTTATGCTTTTCAACAAAAAGCAAC TGAGTTTACATCAGCACATATACTAAAAGCTCTTTTGGAGCAAAATGATAGTGTTGCTATATCTATATTAAGCGTTTGTG GTGTTAATATACAAAACTTTATAAAAGCTGTAAATGATATGGTTGATAGTGTTGCGGTATTATCTGGAGAAGGTAACCCT CAAGTAACACCATCTAGAGATTTAATAGCTACATTACATAAAATGCAAGGGCTTGCTAATAAAAATGATGATGAGTTTAT CTCGAGTGAGGTTTTCTTATTAGCCTCTTTAGAAGATAAAAGTTTAACTGGACTGTATAACAAATTCGGTATTACAAAAG AAAAATTAACAAAAGCAGTCAATGATTATCGCGGAGGGGAGAAAGTGAGTAGTCAAAATCAAGAAGATATGAAAGGTGCA TTAGATAAATACACGGTAGATCTAACTGATCTAGCGAGAAAAGGAAAAATTGATCCAATAATCGGTAGAGATAGTGAGAT CCGTAGAACTATTCAAGTATTACAAAGAAGAACTAAGAACAACCCTGTGCTTATAGGTGAGCCTGGTGTTGGTAAAACTG CTATTGTTGAGGGCTTAGCTCAACGAATAGTTAATGATGAAGTACCAGAAGGTGTCAAAGGTAAAAAAGTACTATCATTA GATATGGGTGCACTGCTAGCTGGTGCTAAATTTAGAGGAGATTTTGAAGAGCGTCTAAAATCTGTATTAAAAGAGCTATC AAAACAAGAAGGTAATGTAATTCTCTTTATAGATGAATTACATACTATGGTAGGTGCTGGTAAAGCAGAAGGATCTATGG ATGCTGGTAACATGCTTAAACCTGCTCTAGCTAGAGGAGAGCTAAAGTGTGTTGGTGCAACAACTTTAGATGAGTATCGT GAGTATGTTGAAAAAGATCCGGCACTTGAGCGAAGATTCCAGAAAGTGCTAGTTGATGAACCTACTGTAGAAGATACTAT CGCTATACTTAGAGGCCTAAAAGAAAGATATGAGCTACATCATGGTGTAAATATCACAGATTCAGCTATTGTAAGTGCAG CAACTTTGTCACATAGGTATATCACAGATAGACAGCTACCTGATAAAGCTATAGATCTAGTAGATGAAGCAGCAAGCCAA ATTCGTATGGAAATAGACTCTAAACCTGAAAAAATGGAAAGCTTATATCGTAGAATCATCCAGCTGAAAATGCAACGCGA ACAGCTAAAGAAAGAGAAAGATGATGCTACTAAAAAACGTTTAGAGATACTTGAGCAAGAAATAAAAGGGCTAGACTCCG AGTATAAAGGACTAGAAGAGCTTTGGAAAGCTGAAAAACTTAAGATGCAAGGTACAAGTAAACTAAAAGAAGAGCTTGAG AAAGCCAAGTTTGAACTTGAAAAGTACCAAAGAGTGGGTGATTTGAGCAAAATGGCAGAATTACAATACGGTAAAATACC TGAGCTAGAAGCACAAATTAAACAAATAGAAGAAACTGAAGCAGAACCTTCTGAAAACAAATTAGTAAGAACATCTGTTA CAGAAAATGAGATTGCTGATGTAGTTTCAAAAGCTACTGGAATACCTGTGTCTAAGATGATGGAAGGCGAAAAAGACAAG CTTCTAAATATGGAAAGTTTCTTACATAAAAGAGTAATCGGACAAGATCAAGCTATAAAAGCAGTATCAAATGCTGTAAG AAGATCTCGTTCTGGATTATCAGATCCAAATAGACCTATAGGCTCATTCATGTTCTTAGGTCCAACTGGTGTCGGTAAAA CTGAGCTTACAAAAGCTTTAGCAGAGTTTTTGTTTGATGATGAAGATGCCATGCTTAGAGTAGATATGTCTGAGTTTATG GAGAAACATTCTGTAGCTAGACTAATAGGCGCACCTCCTGGATACGTAGGTTATGAACAAGGCGGCTATCTAACTGAACA TGTTAGAAGAAAACCTTATTCTGTAATCTTACTTGATGAGGTTGAAAAAGCTCATGCTGATATATTTAACATCTTACTAC AAGTGCTTGACGATGGTCGCCTAACAGATGGGCAAGGCAGAACAGTAGACTTTAAAAATACTGTAATAGTTATGACTTCT AACCTTGGTTCACATCGAATCCAAGAAATGCAAGGTCAGGATTATGAAACAGTAAAATCTGCTGTAATGGAAATGGTACT TAGCCACTTTAGACCTGAATTTGTAAATAGAGTTGATGATGCAATTGTCTTTGAACCTCTAAACAAAGAGATGATAACTG AAATAGCTAAAATACAAATCAAACGCTTAGAAAAACGTCTAGCAGATCTAAGTATAGGATTAGAAGTCACAACTGAAGCT ATGGATAAACTAGCTGATGCTGGCTTTGATCCTGTGTTTGGTGCTAGACCGCTTAAGCGCGCTATTCAAAACAACTTAGA AAACCCTCTGGCTCTAAAACTTCTAGATGGTGAGTTTAAAGCTGAAGATAAAATAGTTGTCGATATTGACGCTAATAACA ATATTACATTCTCTAAATAA Protein sequence : MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNFIKAVNDMVDSVAVLSGEGNP QVTPSRDLIATLHKMQGLANKNDDEFISSEVFLLASLEDKSLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGA LDKYTVDLTDLARKGKIDPIIGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSL DMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLKPALARGELKCVGATTLDEYR EYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQ IRMEIDSKPEKMESLYRRIIQLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELE KAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIADVVSKATGIPVSKMMEGEKDK LLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPIGSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFM EKHSVARLIGAPPGYVGYEQGGYLTEHVRRKPYSVILLDEVEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS NLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQIKRLEKRLADLSIGLEVTTEA MDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFKAEDKIVVDIDANNNITFSK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 2e-106 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_762773.1 | endopeptidase Clp | VFG2076 | Protein | 5e-117 | 41 |
