Gene Information

Name : wecC (FTH_0596)
Accession : YP_763197.1
Strain : Francisella tularensis OSU18
Genome accession: NC_008369
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : 1.1.1.-
Position : 586201 - 587511 bp
Length : 1311 bp
Strand : +
Note : UDP-N-acetyl-D-mannosaminuronate dehydrogenase

DNA sequence : 
ATGAGTTTATATGAGGATATAGTCGCTAAAAGAGAAAAGGTTTCATTGGTTGGCTTGGGTTATGTTGGTTTACCAATAGC
TATTGCATTTGCAAAAAAAATAGATGTGTTAGGATTTGATATTTGTGAAACAAAAGTTCAACATTATAAGGATGGTTTTG
ATCCAACAAAAGAAGTAGGAGATGAGGCTGTCAGAAATACGACAATGAAATTTAGTTGTGATGAAACAAGTCTTAAAGAG
TGTAAATTTCATATTGTTGCAGTTCCTACACCAGTTAAAGCAGATAAAACTCCTGATTTGACGCCGATTATTAAGGCAAG
TGAGACGGTTGGTAGGAATCTTGTCAAAGGCGCTTATGTTGTGTTTGAATCAACTGTTTATCCTGGTGTTACAGAAGATG
TTTGCGTACCAATACTTGAAAAAGAGTCTGGCTTGAGGTCTGGTGAAGATTTCAAAGTTGGTTACTCTCCTGAGAGGATA
AATCCTGGTGATAAGGTTCATAGGTTAGAAACAATTATCAAAGTAGTATCTGGTATGGATGAAGAGTCTTTAGATACTAT
AGCAAAAGTTTATGAGCTAGTAGTAGACGCAGGAGTTTATAGAGCTAGTAGTATAAAAGTGGCTGAAGCTGCTAAGGTTA
TAGAAAACTCTCAAAGAGATGTTAATATAGCTTTTGTTAATGAGTTATCGATAATATTTAATCAGATGGGTATTGATACT
CTAGAGGTTTTAGCAGCAGCTGCAACTAAATGGAATTTCTTAAACTTTAAGCCTGGTCTTGTTGGTGGACATTGTATTGG
TGTTGACCCATATTACCTAACGTACAAGGCAGCTGAGCTTGGATATTATTCTCAGGTAATATTATCTGGTCGTAGGATAA
ATGATGGTATGGGCAAATTTGTAGTTGAGAATTTAGTCAAAAAACTGATATCTGCAGATATACCTGTTAAGCGAGCTAGA
GTAGCAATTTTCGGCTTTACTTTTAAAGAAGACTGTCCTGACACTAGGAATACTCGAGTTATAGATATGGTAAAAGAGCT
CAACGAGTATGGTATAGAGCCATATATTATAGATCCGGTAGCTGATAAAGAAGAGGCTAAACATGAGTATGGACTTGAGT
TTGATGATCTAAGTAAAATGGTCAATCTAGATGCGATCATTATTGCTGTTAGTCACGAACAGTTTAAAGATATAACAAAG
CAACAGTTTGATAGGCTATATGCGCATAATTCTAGAAAGATTATCTTTGACATCAAAGGTAGTTTAGATAAATCTGAGTT
TGAAAAAGATTATATTTATTGGAGATTGTAG

Protein sequence : 
MSLYEDIVAKREKVSLVGLGYVGLPIAIAFAKKIDVLGFDICETKVQHYKDGFDPTKEVGDEAVRNTTMKFSCDETSLKE
CKFHIVAVPTPVKADKTPDLTPIIKASETVGRNLVKGAYVVFESTVYPGVTEDVCVPILEKESGLRSGEDFKVGYSPERI
NPGDKVHRLETIIKVVSGMDEESLDTIAKVYELVVDAGVYRASSIKVAEAAKVIENSQRDVNIAFVNELSIIFNQMGIDT
LEVLAAAATKWNFLNFKPGLVGGHCIGVDPYYLTYKAAELGYYSQVILSGRRINDGMGKFVVENLVKKLISADIPVKRAR
VAIFGFTFKEDCPDTRNTRVIDMVKELNEYGIEPYIIDPVADKEEAKHEYGLEFDDLSKMVNLDAIIIAVSHEQFKDITK
QQFDRLYAHNSRKIIFDIKGSLDKSEFEKDYIYWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-109 54
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-103 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-103 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wecC YP_763197.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 9e-104 54