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Name : FTH_0592 (FTH_0592) Accession : YP_763193.1 Strain : Francisella tularensis OSU18 Genome accession: NC_008369 Putative virulence/resistance : Virulence Product : dTDP-glucose 4,6-dehydratase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1086 EC number : 4.2.1.46 Position : 581948 - 583684 bp Length : 1737 bp Strand : + Note : - DNA sequence : ATGTCTTTCTACGATAATAGAACGCTTAATTTCGTGGTAATAATAGTTTTAACTATTATTACTGTTAATTGGACTTTCTA TATTTTCAAGCAAGATGTTAATTTACATTTTTTACTTGCATTAGTTTTGCTGAGATGCTTGTCATCTTTTTTACTACTTA GAGATTATATGGCTAGTTGGCGTAAGTCGACTCAAAAAACTTTTTTACGTAAGGCTTTTATTAATTTGCCAGTATTTTTC ATAGTGGCATTATTTTTTTATGGCAAAGTCACTTTTTCGTTGATATTCTCTGAGTTTTTATTTTATGTTTTTTTGATCAG TTTAAGTGTCTACTTTTATTGGTATTTGATGAACAGAGGATCAGTGGATAAAAGTAAAACTGCGGTTATTTATGGTGCAG GTGCTGCAGGAACAAAGATTGCTCAAGAACTTGCTTCTGCTGGTTATCGCATCAAATGTTTTGTTGATGACAATGAAACT TTACAAAAAAGAAGTATTGATAGTAAAAAGGTTCTATCTAAAGCTGAATTAACAAAACTATTGCTATCTAGTAGATTTGA CCTTTTGGTTATTGCATTGCCAAGAAATGCAAACCAAGTAGTCAAAAATATATATAAAGAATTTGAAAAGGATTTTAATC AGATTAGAATTATGCCGCCTCTTGAGGAAATTCTTCAAGATGAGAATTTTATGTCACAGTTGAAGCCTGTTTCACTCTAT GATCTATTAGCGCGTGATACTAAGAGTTTAGATAAAGAATCTATCTCTAATTTTATCAAAAATAAGGTAGTGCTAGTCAC AGGAGCTGGAGGTAGTATAGGTTCTGAAATAGTACATCAATGTATCAAGTATCAGGCAAAAGAGTTGATATTGGTTGATC ATAGTGAGTTTAACTTATATAAAATTACTGAGGAGTGTAGTCATTTTAATATCAATAGTGTGCTATGTTCTGTTTGTGAT AGAAAAGCATTGGCTGAGGTTTTTCAAAAGTATACTCCAAATATAGTATTTCATGCTGCTGCCTACAAGCATGTTCCCTT AGTTGAGGAGAATATCTCTAGAGCAATTAGAAATAATATCTTAGGTACTAAGAATGCTATAGATCTGGCTATAGAAGCTG GTGTTGAGTCATTTATATTGATTTCCACTGATAAAGCAGTGCGACCAACGAATGTTATGGGGGCTACCAAGAGAGTTTGT GAGCTGTATTTACAGAATGTTGATCCCAAAAATACCAAGCTTGCTGCAGTGCGTTTTGGTAATGTGCTTGGTAGTAGTGG CAGTGTGATTCCAAAATTTGAAGAGCAAATAAGAAATGGTGGTCCTGTTACAGTTACTCATCCTGAAATTACACGTTATT TTATGTTGATACCAGAAGCTTGTGAACTGGTCCTACAAGCTGGTGCTATTGCAAAAAATTCAGAGGTCTTTGTCTTAGAT ATGGGGCAACCTGTCAAGATTATTGATCTTGCTAAACAATTTATTAGACTTTCTGGTAGAGGTGATATTGATATTAAAAT AGTTGGTTTGCGTCCAGGAGAGAAACTTTACGAAGAGCTTTTGATAGAGGAAGATGATGTTAGTACCGACTATAAAGATA TTTTTATTGGTAGAAGGACTTTTTACGATATTAATACTCTAAACCAAGATATTGAATCGTTGATCAAGGATGATGTTGAT CAGCTTGTGATATTAAAGAAAATTGTTCCGGAATTTGAACATAGATTGAATGGGTAG Protein sequence : MSFYDNRTLNFVVIIVLTIITVNWTFYIFKQDVNLHFLLALVLLRCLSSFLLLRDYMASWRKSTQKTFLRKAFINLPVFF IVALFFYGKVTFSLIFSEFLFYVFLISLSVYFYWYLMNRGSVDKSKTAVIYGAGAAGTKIAQELASAGYRIKCFVDDNET LQKRSIDSKKVLSKAELTKLLLSSRFDLLVIALPRNANQVVKNIYKEFEKDFNQIRIMPPLEEILQDENFMSQLKPVSLY DLLARDTKSLDKESISNFIKNKVVLVTGAGGSIGSEIVHQCIKYQAKELILVDHSEFNLYKITEECSHFNINSVLCSVCD RKALAEVFQKYTPNIVFHAAAYKHVPLVEENISRAIRNNILGTKNAIDLAIEAGVESFILISTDKAVRPTNVMGATKRVC ELYLQNVDPKNTKLAAVRFGNVLGSSGSVIPKFEEQIRNGGPVTVTHPEITRYFMLIPEACELVLQAGAIAKNSEVFVLD MGQPVKIIDLAKQFIRLSGRGDIDIKIVGLRPGEKLYEELLIEEDDVSTDYKDIFIGRRTFYDINTLNQDIESLIKDDVD QLVILKKIVPEFEHRLNG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cap1D | AAA64643.1 | type 1 capsule synthesis gene | Virulence | SCCcap1 | Protein | 2e-75 | 44 |
| SSP0063 | YP_300153.1 | capsular polysaccharide biosynthesis protein | Not tested | SCC15305cap | Protein | 6e-71 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| FTH_0592 | YP_763193.1 | dTDP-glucose 4,6-dehydratase | VFG1300 | Protein | 1e-74 | 42 |
