Gene Information

Name : rph (FTH_0352)
Accession : YP_762993.1
Strain : Francisella tularensis OSU18
Genome accession: NC_008369
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 335448 - 336155 bp
Length : 708 bp
Strand : +
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
ATGCGTCCAAGTGGTAGAAATAATGATCAACTACGTAATCTAAAAGTTACACATAATTTTACAAAACATGCCGAGGGCTC
TGTCCTTATTGAATTTGGAGATACTAAAGTTATCTGTACAGCTTCTGTAGTTGCAGGTGTACCAAAATTTAAAAAAGATA
GTGGTGAGGGTTGGCTAACAGCAGAATATGGCATGTTGCCGCGTTCAACTCATACGCGTATGGATAGAGAGGCAGCACGT
GGTAAGCAATCTGGAAGAACTCAAGAAATTCAGCGCCTGATAGGTAGAGCATTGCGTGCTAGTGTTGATCTTACAGCTAT
CGGGGAAAATACTATTAAGGTTGATTGTGATGTGATTCAAGCTGATGGTGGTACGCGTACTGCATCGATTACCGGCGCAT
CATTAGCCATAGCTGATGCTATAGAATATATGAAACAAAATGGTATATTAGATGAGCAGGCAAATCCACTATTATCACAA
GTGGCAGCAATATCTGTAGGTATTTATAATAACGAGCCAGTGCTTGATCTTGATTATGATGAAGATTCAAACGCAGAAAC
TGATATGAATGTAGTGATGAATTCAAATGGCGGTATAATCGAGATTCAAGGCACTGCTGAAGGCAAAGACTTCTCTGAAG
AAGAGTTTGCAAAAATGCTTGGTCTTGCTAAAAAAGGTATCAAAGAGATTTTTGCAACAGTATTCTAG

Protein sequence :
MRPSGRNNDQLRNLKVTHNFTKHAEGSVLIEFGDTKVICTASVVAGVPKFKKDSGEGWLTAEYGMLPRSTHTRMDREAAR
GKQSGRTQEIQRLIGRALRASVDLTAIGENTIKVDCDVIQADGGTRTASITGASLAIADAIEYMKQNGILDEQANPLLSQ
VAAISVGIYNNEPVLDLDYDEDSNAETDMNVVMNSNGGIIEIQGTAEGKDFSEEEFAKMLGLAKKGIKEIFATVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 3e-67 59