Gene Information

Name : mutS (FTH_0294)
Accession : YP_762944.1
Strain : Francisella tularensis OSU18
Genome accession: NC_008369
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 280441 - 283008 bp
Length : 2568 bp
Strand : -
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
TTGCTAACAAAAAGATTCTACAATTTAGCTATTATGCAAGATATTTCTAATCACACCCCGATGATACAACAATATTTGAA
AATTAAATCACAGTATCAAGATATATTATTATTTTACCGTATGGGCGATTTTTATGAGCTTTTTTTTGATGATGCTAAAA
AAGCTGCTGAGCTCTTAGATATTACGCTCACAGCTCGTGGTAAATCAAATGGTGAATCAATCCCGATGGCTGGAGTGCCA
TATCATGCCGCTGAAGCCTATATTGCAAAAATTGTCAAAAAAGGTCTATCGATTGCTATCTGTGAGCAAACTGGCGATCC
AAACACCTCAAAAGGTCCCGTTGAGAGACAAGTGACACGTATTATAACTCCAGCGACAGTTTCTGAAGAAGCTTTTTTAG
ACAACAATCAAGATAGTATTCTTGTGAGTATTTTTGAAAAAAATAATAAGTATTATTTAGCATACACAAGCTATACGCAA
GGAAAAATTTATCTAGTTAAAACACTAACTAGCCTAAATGAGCTAAAAAATACTGTTCTGAAATTATCACCTCAAGAAAT
TATTACTAACTCTCGAGAACTTGCTCAGCAGAATCCTTTTAAAAAACCAATTAAAGCTTTAGAAGAATGGTATTATAGTA
ATTTTGAGGCAAAAAAATATATCAATGATTCTCTTGATACCAATATTGCTAATAATATCCTAAATCTTTATAAAAATGAT
CAACTAACAACTATTGGCTCAATACTTAGCTACCTTACAAATATTCTCAAGGATACTCCTAGGCATATTACTGATATCAG
CTATGAACAAGAACAAGATACGCTTAACATTGATATAAATAGTCGTATAAATCTTGAGCTAGATAATAACTCAAAAAGTA
GCTTACTTAGCATAATTGGTAAATGTAAGACTAGCCTTGGTAGTCGTTTACTAAAAAGGTATTTTAGCAATCCAACAAGA
AATTTAAACATTTTAGCTACTCGCCATAGTATTATAAACAGTTTAGGTGAAAATCAACATTTTTTAAAAATTCAAGATGT
GCTTAGTTATATCAGTGATATTGAAAGGATAATCTCACGAGTAGCACTTGGAACTGTAAAACCTAAAGATCTTGTCGCTC
TGCGTTACTCCCTTGAGCAGCTACCAATACTCAAAAAACTCCTCAGTGAAAAAAATACTCCAGAGATTACAAATATAAAT
AACCGCATCCACCAGCTTGATGAGCTTGTTACACTTTTAGATAAAGCGATTATTGAGAATCCCCCAACAACCATTCGTGA
TGGTGGCGTCATCAAAGAAGGTTTTGATAAAGAACTAGATGAGCTAAAAAGCATAAAAGATAATTCTTATGATTTTCTAA
TCAAGTTTGAAGAATTACAAAAACAGAAAATTGGTATAAGTACACTCAAAGTTGGTTACAATCGTGTTCATGGCTATTAT
ATTGAGTTATCTAAACAGCATGCTGATAAAATCCCAACTGAGTATGTCAGACGCCAAACCTTAAAAGCTAGTGAACGCTA
TATCACCGAAGAACTAAAAAACTTCGAAGATAAAGTCCTTTCATCAAAAGAAAAGGCTCTAGCCCGTGAAAAGTTAATCT
ATGATACTCTATTAAAGAAAGTTATCGAATACTACAAACAAATTCAAGAAACTGCTGCAAGTATTGCTGAAATAGATGTT
TTAGCAAATTTTGCTGAGAGAGCTATTAAGCTTAAACTTAGTCAACCTAAGTTTAATAACTTAGCAAAATTAGAACTTAA
AGAAGTTCGTCACCTTGCTATTGAGCATAATATTGATGAACCATTTATCCCAAACGATACTTTACTAAGCAAAGATACTA
ATACCCTACAAATAATAACTGGTCCAAATATGGGCGGTAAATCGACATATATGCGCCAAGTTGCACAGCTAATATTTCTA
GCTTATATCGGCTCATTTGTACCAGCAAGTTATGCAGATATTTGTGATATTGATACTATCTACACAAGGATTGGTGCATC
TGATGATATTTCTAGCGGTAGATCAACTTTTATGGTTGAAATGACTGAAACAGCCTATATTCTCAATAATGCTAGTGCCA
AATCACTAGTAATAATGGATGAAATAGGTCGTGGCACAAGTACTTTTGATGGTTTAGCATTAGCTAAAGCATGTGCAGAG
AAGTTTGCACAAATGGGGGCTTTTACTTTATTTGCAACACATTATTTTGAGCTAACAGAATTGGCTAAACAATATCCAAA
TGTATGTAACATCCATTTTGAAGCAAAAGAATATAAAGATAATATCTACTTTATGCACAAAGCTGTTACAGGAGCGGCTA
AAAAATCCTATGGCATCCAAGTAGCCAAACTTGCCGGAATATCTCAAGATGTCCTAGAGTCAGCAAAGCAAAATTTATAT
AATCTCGAAAAAAAGCAACAGCTAACAGAATCAACCCAAGTCCAAGCTCAATTTCAGTTAGAACCAACAACTCAAAATCC
TTTACAACAAAAACTTGATGCTATCGATATTAATACAATAACACCTCTAGAAGCACTAAATATTCTCTTTGAACTAAAAA
AACGCTAA

Protein sequence :
MLTKRFYNLAIMQDISNHTPMIQQYLKIKSQYQDILLFYRMGDFYELFFDDAKKAAELLDITLTARGKSNGESIPMAGVP
YHAAEAYIAKIVKKGLSIAICEQTGDPNTSKGPVERQVTRIITPATVSEEAFLDNNQDSILVSIFEKNNKYYLAYTSYTQ
GKIYLVKTLTSLNELKNTVLKLSPQEIITNSRELAQQNPFKKPIKALEEWYYSNFEAKKYINDSLDTNIANNILNLYKND
QLTTIGSILSYLTNILKDTPRHITDISYEQEQDTLNIDINSRINLELDNNSKSSLLSIIGKCKTSLGSRLLKRYFSNPTR
NLNILATRHSIINSLGENQHFLKIQDVLSYISDIERIISRVALGTVKPKDLVALRYSLEQLPILKKLLSEKNTPEITNIN
NRIHQLDELVTLLDKAIIENPPTTIRDGGVIKEGFDKELDELKSIKDNSYDFLIKFEELQKQKIGISTLKVGYNRVHGYY
IELSKQHADKIPTEYVRRQTLKASERYITEELKNFEDKVLSSKEKALAREKLIYDTLLKKVIEYYKQIQETAASIAEIDV
LANFAERAIKLKLSQPKFNNLAKLELKEVRHLAIEHNIDEPFIPNDTLLSKDTNTLQIITGPNMGGKSTYMRQVAQLIFL
AYIGSFVPASYADICDIDTIYTRIGASDDISSGRSTFMVEMTETAYILNNASAKSLVIMDEIGRGTSTFDGLALAKACAE
KFAQMGAFTLFATHYFELTELAKQYPNVCNIHFEAKEYKDNIYFMHKAVTGAAKKSYGIQVAKLAGISQDVLESAKQNLY
NLEKKQQLTESTQVQAQFQLEPTTQNPLQQKLDAIDINTITPLEALNILFELKKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 1e-159 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS YP_762944.1 DNA mismatch repair protein MutS VFG0562 Protein 7e-180 45