Gene Information

Name : purA (FTH_1850)
Accession : YP_764232.1
Strain : Francisella tularensis OSU18
Genome accession: NC_008369
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 1861219 - 1862505 bp
Length : 1287 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGTCAAATATCGTAATCGTAGGCGCTCAGTGGGGCGATGAAGGTAAAGGTAAAATAGCAGATACTTTAGCTGAGAAAGC
CGATTTGGTTGTTCGTTATCAAGGTGGTAATAACGCTGGTCATACATTGGTTGTAAATGGTAAGAAGACATTTCTTCATT
TAATACCTTCAGGTGTTTTGCATCAGCATACAAAATGTGTAATTGGTCATGGCGTGGTTTTAGATCCTGTTGCCTTAGAT
GAGGAAATTACACGTCTACAAGCAAAAGGTATAGCAATTTCAGCAGAGAATTTATTTGTTTCTGAGTCTTGTACGATTAT
TACTTCTTATCATAAACTTTTAGATGCAGTTAGAGAAAGTAACACTAGTGAGAAAATAGGTACGACTGGTAAAGGTATTG
GTCCAGCATACGAGGATAAAGTATCGCGTAAAGGTATTAAATTTAAGCATCTATTTGATAAGGATTTATTAAGATCAAGG
TTAGCAATCTCTTTGGCAGAGAAAGAAACTTTATTTAGAGATTTATATAAAGTCGAATATCCAACACTAGAACAAGAATT
TGATAAGCTTTTTGCTTTGGGTCAAAAACTTAAACAGTATGCAGCAGATACTTTTTCAATAATAGATCAAGCAATTGCAG
CGGGTAAGAATGTTGTTTATGAAGGTGCACAAGGTGTGCTTTTAGATGTTGATTATGGTACTTATCCATTTGTGACATCT
TCTAATACTTCAGTGGCGGGAGTATATTCTGGTGCAACCACTGCCGGACATGGTTTAGATCATGTGATTGGGATTACAAA
AGCTTATACTACAAGAGTTGGTGAAGGACCTTTCCCAACAGAGCTTTTTGATGATGTTGGTAAATTTATTCAGCACAAAG
GTGGCGAGATAGGTGTGACAACTGGTAGAATTCGTAGGTGTGGTTGGTTAGATTTACCTCTTTTAAAATACTCAGCAAAA
TGCTCAAACTTAACATCAATAGCCTTAACAAAGGTTGATGTTTTATCTGATATGGACACTCTAAAAGTTTGTATTGGTTA
TAAGTATGAGGGCAAAGAAATATATTGTGCTTATCCAGGAATAGATCTTTACAAGGTAGAGCCAATTCTTGTCGAAATGG
AACCGTTTTCTATAGATGAAACAGTAACAAAAGATAATATGCCAGCTGCTCTTAAGACATATCTTAAGACTATAGAGAAT
CACGTTGGTATTCCAATATCTTCATTAGCTTATGGACCATCTAGAGAACAAATTTTATTCTTTGAGGATTATTTCAAAAA
GGGTTAA

Protein sequence :
MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD
EEITRLQAKGIAISAENLFVSESCTIITSYHKLLDAVRESNTSEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRSR
LAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTS
SNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAK
CSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEIYCAYPGIDLYKVEPILVEMEPFSIDETVTKDNMPAALKTYLKTIEN
HVGIPISSLAYGPSREQILFFEDYFKKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 5e-90 46