Gene Information

Name : serS (FTH_1445)
Accession : YP_763894.1
Strain : Francisella tularensis OSU18
Genome accession: NC_008369
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1418802 - 1420082 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATGCTAAATATGTTAAGGATAATTTACAACAAGTTGCTGAAAAGCTTGCAACTAGAGGTTATCAATTTGATAT
AGCCGAATTTGAAGCCCAAGAGCAAAAAAGAAAACATCTTCAAGAAAGAACTCAGGATCTACAATCACAACGTAATACTA
TTTCAAAAGAAATAGGCCAAAAAAAAGCTAAAGGTGAAGATACTAGTGATATCTTTGCTAAAGTTAATCAAATTAATGAA
GAACTAAAAATTATTGAAAAAGAGCTCAAAGACCTACAAGATACTATAAATCAAACACTATTATCAATGCCAAATCTTCC
TGCTGATGACGTCCCTGTTGGTAAAGATGAGAATGATAATGTAGAAATAAGAAGATGGGGAACTCCACGTGAGTTTCATC
CTGAAGCACCTGCAAAAGATCATTCTGATATTGGTGAAATCCTCAAAATGATTGATTTTAAAGCCGCTGCTAAAGTTACT
GGCAGCCGCTTTATGGTCCTGAAAAATAAGATTGCTAAACTACACCGCGCTCTATCACAGTTTATGCTTGATCTGCATAC
AGAAAAACATGGTTATGAAGAATTATATGTGCCATATCTAGTCAATAATGATAGTTTATATGGTACTGGACAATTACCAA
AATTTGCTGCTAATCTTTTTAAGCTTGAGGGAGATTTTGAATATAGTCTAATACCTACAGCAGAGGTGCCAATCACTAAT
CTAGTAAGGGATGAAATTTTAGATACAGAAACTTTACCTAGATACTATACAGCTCACACTCCTTGCTTTAGAAGTGAAGC
TGGTTCATATGGCCGTGATACTAAAGGTATGATTCGTCAACACCAGTTTGAGAAAGTCGAGTTAGTACATATCACTACTG
CAGATAAAGGTGAAGAATCTCTAGAATTACTCACATCACATGCTGAAAAAGTCTTACAAAAACTTAACTTACCATATAGA
GTGATGAAACTATGTACTGGTGATATGGGCTTTAGCGCTAAAAAAACTTATGATTTAGAAGTATGGCTCCCATCACAAAA
TACTTATAGAGAAATATCTTCATGTAGCTGGTGTGGAGATTTCCAAGCTCGTCGTATGAAAGCTCGACACAAAAATCCAA
GTATGAAGAAACCAGAATTAGTCCATACTCTAAATGGTTCTGGTTTGGCTGTAGGTAGAACATTATTAGCTATTATTGAA
AATTATCAACAAGAAGATGGTTCTATTATGGTTCCCGATGCTCTTATCAAGTATATGGGCGGAATTTCAGTTATTAAGTA
A

Protein sequence :
MLDAKYVKDNLQQVAEKLATRGYQFDIAEFEAQEQKRKHLQERTQDLQSQRNTISKEIGQKKAKGEDTSDIFAKVNQINE
ELKIIEKELKDLQDTINQTLLSMPNLPADDVPVGKDENDNVEIRRWGTPREFHPEAPAKDHSDIGEILKMIDFKAAAKVT
GSRFMVLKNKIAKLHRALSQFMLDLHTEKHGYEELYVPYLVNNDSLYGTGQLPKFAANLFKLEGDFEYSLIPTAEVPITN
LVRDEILDTETLPRYYTAHTPCFRSEAGSYGRDTKGMIRQHQFEKVELVHITTADKGEESLELLTSHAEKVLQKLNLPYR
VMKLCTGDMGFSAKKTYDLEVWLPSQNTYREISSCSWCGDFQARRMKARHKNPSMKKPELVHTLNGSGLAVGRTLLAIIE
NYQQEDGSIMVPDALIKYMGGISVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-101 54