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Name : guaA (FTH_1046) Accession : YP_763571.1 Strain : Francisella tularensis OSU18 Genome accession: NC_008369 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 1027173 - 1028723 bp Length : 1551 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACAGATATACATAATCATAAGATTTTGATTTTAGATTTTGGCTCGCAATATACACAACTTATTGCTCGTAGAGTAAG AGAAGTAGGTGTTTTTTGTGAAATTTTCCCTCATGATGTAGCAGCTGATTTTATCAAAAATTATCAAGCAAAAGGAATAA TTTTATCAGGTGGTCCTGAGTCAGTTTATGATTCTGATGTCAAAGCTCCTGAGATAGTTTTTGAGCTTGGAGTACCTGTT TTGGGTATTTGTTATGGCATGCAAACAATGGTAATGCAGCATGGTGGCGAAGTAAAAGGAGCTGATCAAAGTGAATTTGG TAAGGCAATTATAAATATCCTAAATTTAACAAATAACATATTTTCAAATATGGAGCATGAGCAGCTAGTTTGGATGAGTC ATAGTGACAAAGTCACTCAAACTGGTGAGCATTTTGAGATAATTGCTTCTTCAACAAATGCTCCAGTTGCGGCAGTTGCA CATAAAAATAAGCCTTTTTTTGGTGTGCAGTTTCACCCAGAAACTACTCATACAGAAAATGGTAAGCAAATTATTGAGAA TTTTGTCGTTAATATCTGCGGATGTGATACTCTGTGGAATATCGAAAACATTATCGAAAATGATATAAAAGAAATTAAAC AAAAAGTTGGTACTGATAAAGTAATTTTAGGGCTATCTGGAGGTGTTGATTCATCTGTTGTAGCTGCGATATTACATCAA GCTATCGGCGATCAGCTAACTTGTATATTTGTAGATACTGGTTTACTGCGCCTTAATGAGGGTGATCAAGTTATGCAAGT ATTTGCAGAGCATATGGATATTAATGTTATTCGTATCAATGCAAAAAATAGATTCTTAGATGCCCTAAGGGGTATCTGTG ATCCAGAACAAAAACGTAAAATTATCGGTAAGCTATTTGTTGATATTTTTGATGAAGAGGCTGCTAAGATAGAGAATGCT AAATGGCTTGCGCAGGGCACTATCTACAGTGATGTAATTGAATCAGCTGGCAATAATCAGTCTAAAGCACATGTAATTAA ATCACATCATAATGTTGGTGGCTTACCAAAAGAAATGAAACTTAAGCTTTTAGAACCATTAAGAGAGCTTTTCAAAGATG AGGTTCGTAAATTAGGCTTAGGTTTAGGATTACCTTATAATATGCTTTATAGACATCCATTTCCTGGTCCTGGTCTTGGA GTACGTATATTAGGTGAAATAAAGAAAGAGTATGTAGAAACGTTACAAAAAGCTGATGCTATATTTACAGAAGAGCTTTA TAAACATAATTTATACCATGATGTTTCTCAAGCTTTTGGGGTGTTTTTACCTATCAAATCGGTAGGTGTAGTTGGTGATC AGCGTAGATATGAGTATGTAATAGCTCTAAGAGCTGTCGTTAGTATCGATTTTATGACTGCAACGTGGGCTAATTTACCT TATGATTTTCTGTCACTAGTTTCAAATAGAATTGTAAATGAAGTAAAACAAGTATCAAGAGTTGTGTATGATGTGACAGG AAAACCACCTGGAACAATTGAATGGGAATAA Protein sequence : MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDVAADFIKNYQAKGIILSGGPESVYDSDVKAPEIVFELGVPV LGICYGMQTMVMQHGGEVKGADQSEFGKAIINILNLTNNIFSNMEHEQLVWMSHSDKVTQTGEHFEIIASSTNAPVAAVA HKNKPFFGVQFHPETTHTENGKQIIENFVVNICGCDTLWNIENIIENDIKEIKQKVGTDKVILGLSGGVDSSVVAAILHQ AIGDQLTCIFVDTGLLRLNEGDQVMQVFAEHMDINVIRINAKNRFLDALRGICDPEQKRKIIGKLFVDIFDEEAAKIENA KWLAQGTIYSDVIESAGNNQSKAHVIKSHHNVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLG VRILGEIKKEYVETLQKADAIFTEELYKHNLYHDVSQAFGVFLPIKSVGVVGDQRRYEYVIALRAVVSIDFMTATWANLP YDFLSLVSNRIVNEVKQVSRVVYDVTGKPPGTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 3e-119 | 54 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 2e-119 | 54 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-119 | 54 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 3e-98 | 45 |
