Gene Information

Name : tetA (HNE_0492)
Accession : YP_759222.1
Strain : Hyphomonas neptunium ATCC 15444
Genome accession: NC_008358
Putative virulence/resistance : Resistance
Product : tetracycline-efflux transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 484964 - 486217 bp
Length : 1254 bp
Strand : -
Note : identified by similarity to SP:P02981; match to protein family HMM PF00083; match to protein family HMM PF07690

DNA sequence :
ATGACCGACACCGCGCCCGCCCGCCTTCCCGGCAAAAACGCTTTCTTCTTCGTGCTGGTGACGGTCTTCATCGATCACCT
CGCCTTTGGCCTGATCATCCCGGTCCTGCCCACGCTGATCCAGGATCTCGCCAACGTGCCCGCCTCCGGCGCCACCCTCT
GGATCGGCGGTCTCGCGGCCACCTATGCCGTGATGACGTTCCTGTTCGGCCCGCTGATCGGCGCCCTGTCCGACAAGTTC
GGCCGCCGCCCGGTCCTGCTCGTCTCGATGGCGATGCTGGGGCTCGACTTTCTGCTGATGGCGCTGGCCCCCAACATCTG
GATACTCTTCCTCGGCCGCGCGCTCGCGGGCATATCGGGCGCCACCTACTCAACCGCCAACGCCTACATTGCCGATACGA
CGACCCCGGAGGAACGCGGCCGCGCCTTCGGCTTTATCGGCGCCTCCTTCGGCCTCGGCTTCATTTTCGGCCCGGTGATC
GGCGGCCTGCTCGGCGAGCTTGGCCCCCGCATACCCTTCTTTGCCGCCGTGGGCCTCGCCTTCCTCAACTTCCTCTACGG
CGTATTCGTGCTGCCCGAATCCCTCCCCAAGGCGCGCCGCCGCAATCTGAACCTTAAGCGCGCCAACCCCCTCGGCGCCG
CCCGCCACTTCTCAAAGCTCCCCAAAGTCTCCTGGTTCCTCATCGCGAGCGGCATTTTCTTCCTCGCCCACACAGTCTTC
CCTGCCACCTGGTCGGTGCATGGCGAGATCCGGTATGACTGGTCGCCCATGCAGATCGGCCTCTCGCTCGGCCTCGTGGG
CGTCGGTGCCGCCACCGTCCAAGCGGGCCTCATGGGCTTTATCCTCAAACGCCTCGGCAGTGTGCGCACCATCATGTTCG
GCTATTGCGTCACCATCATCGCGATGACCGGCTTTGCCTTTGCGGGCCAGCCGCTCTTTGCCTATCTCATCATCCCGTTC
AGCGCGCTCGGCGGCGTCACCATGCCCGCCGCCAACGCCCTGATGTCCAGCCTCACTCCGCCTGACGCGCAGGGCGAGCT
GCAAGGCGCTGCCTCCAGCCTCAATGCGCTGGGCATGATCATCGGCCCCCTGATCATGAGCGGTGCATTGTTCAGCTTCT
CCCGCGAAGACGCGCCTTTGCAATTTGGCGGCGCAGCATTCCTGCTCGCGGCCATTCTCACTGCGCTGGCGTTTCTGCCC
TTCCTGCGCGGGGTCGCCGCCAACCGAGACGTTCTGCCCGCCGCAGCGCCCTGA

Protein sequence :
MTDTAPARLPGKNAFFFVLVTVFIDHLAFGLIIPVLPTLIQDLANVPASGATLWIGGLAATYAVMTFLFGPLIGALSDKF
GRRPVLLVSMAMLGLDFLLMALAPNIWILFLGRALAGISGATYSTANAYIADTTTPEERGRAFGFIGASFGLGFIFGPVI
GGLLGELGPRIPFFAAVGLAFLNFLYGVFVLPESLPKARRRNLNLKRANPLGAARHFSKLPKVSWFLIASGIFFLAHTVF
PATWSVHGEIRYDWSPMQIGLSLGLVGVGAATVQAGLMGFILKRLGSVRTIMFGYCVTIIAMTGFAFAGQPLFAYLIIPF
SALGGVTMPAANALMSSLTPPDAQGELQGAASSLNALGMIIGPLIMSGALFSFSREDAPLQFGGAAFLLAAILTALAFLP
FLRGVAANRDVLPAAAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 3e-42 41
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 2e-42 41
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 2e-42 41
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 2e-42 41
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 2e-42 41
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 1e-42 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetA YP_759222.1 tetracycline-efflux transporter NC_011586.7045189.p0 Protein 3e-39 41
tetA YP_759222.1 tetracycline-efflux transporter NC_010410.6002597.p0 Protein 9e-43 41
tetA YP_759222.1 tetracycline-efflux transporter CP001485.1.gene2821. Protein 9e-43 41
tetA YP_759222.1 tetracycline-efflux transporter AF534183.gene.p01 Protein 8e-43 41