Gene Information

Name : folA (HNE_0463)
Accession : YP_759193.1
Strain : Hyphomonas neptunium ATCC 15444
Genome accession: NC_008358
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 457456 - 457986 bp
Length : 531 bp
Strand : +
Note : identified by similarity to SP:P04174; match to protein family HMM PF00186

DNA sequence :
ATGTCCATTGAAGTGAAACTTTGCCTGATCGTTGCGCAGGCGCGCAACCGGATCATCGGCGCCGCTGGCGCGCTGCCCTG
GCGGCTGAAGGACGATATGGCGTTCTTCAAGGCCACCACCATGGGCGCGCCCGTCATCATGGGCCGCAAGACCTGGGAAA
GCTTCCCCAAACGCCCCCTCCCTGGCCGCGAGAATATCGTGCTCACCCGCGACTGGGATTATGACGCCGCCGAAGCGCGC
GTTTACTCCAGCTTCCCCGCCGCCATGAACGCCGCCCGCGCCATCGCGGCCCGCGAAGGCAAGGACGAAGCCTTCGTCAT
CGGCGGCGCTGAAATCTACGCTCTCGCGCTGCCTTTCGCCGACCGGATCTACCTCACTGAGGTAGATGCCGAGATTGAAG
GCGACACGCTTTTCCCCGAACTCGACCTGCGCCAGTGGCGCAGCGATGAAATCGCCACCCATCCGGCCGGGGAGGGCAAC
GACCATGCCTTCATCATCCGCCGGCTCGACCGCGCCGCCGCTCAGGTCTGA

Protein sequence :
MSIEVKLCLIVAQARNRIIGAAGALPWRLKDDMAFFKATTMGAPVIMGRKTWESFPKRPLPGRENIVLTRDWDYDAAEAR
VYSSFPAAMNAARAIAAREGKDEAFVIGGAEIYALALPFADRIYLTEVDAEIEGDTLFPELDLRQWRSDEIATHPAGEGN
DHAFIIRRLDRAAAQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 6e-20 41