Gene Information

Name : thiC (HNE_3338)
Accession : YP_762011.1
Strain : Hyphomonas neptunium ATCC 15444
Genome accession: NC_008358
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3488534 - 3490426 bp
Length : 1893 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACAAGCCCACCAAGCCCGGCGATTTCGACGCCCCCAAAGTCACCACCGGCGCCCTGCCCGCCAGCCGCAAGGTCTA
TTCGCGCCCCGCGCGCGACCCGGACCTCGCCGTGCCCCACCGCGAGATCGATCTTCATCCGTCAGCGAATGAACCCGCCG
TCCGCGTCTACGACACCTCCGGCCCCTATTCCGACCCCACCGCAGAGATCGACGTGGAGAAGGGCCTCCCCCGCCATCGG
CGCGACTGGCTGCTGGCGCGCGGCGGCCTGGAGGAATATGACGGCCGGGACGTGAAGCCCGAGGACAATGGCGGCGCCAC
CGGCAAATACCTCGCCCGAGAGTTCCCGGTGAAACACATGCCCCTGCGCGGCCTGCCTGGCCAAATGGTGACCCAGTACG
AGTTTGCCAAAGCCGGCATCATCACAAAGGAGATGGTATACGTCGCCGAGCGCGAAAACCTTGGCCGCAGCCAGGCGCTG
GAAAATGCCCGCGCGCAGATCGACCAGGGCAATTCCTTCGGTGCCGACATCCCCGAATTCATCACGCCCGAATTCGTCCG
TGACGAGATTGCCCGTGGCCGCGCCATCATTCCGGCCAATATCAACCATGCCGAGCTGGAGCCTCAGATCATCGGGCGCA
ACTTCCTTGTGAAGATCAATGCCAATATCGGCAATTCGGCGGTCGCTTCCTCCATCGAGGAAGAAGTGGAGAAAATGGTC
TGGGCCACCCGCTGGGGCGCCGACAATGTGATGGACCTCTCCACGGGACGCAACATCCACAACACCCGCGAATGGATCAT
CCGCAACAGCCCCGTTCCGATCGGCACCGTGCCGATCTATCAGGCGCTGGAGAAGGTCAACGGCGTCGCCGAAGACCTCA
CCTGGGAAGTCTACCGCGACACGCTGATCGAGCAGTGCGAACAGGGCGTCGACTATTTCACCATCCATGCCGGTGTGCGC
CTCGCCTATATCCACCTCACGGCCAAGCGCGTCTGCGGCATCGTCTCGCGCGGCGGCTCGATCATGGCGAAATGGATGCT
CGCCCATCATAAGGAGAGCTTCCTCTACGATCATTTCGAGGACATTTGCGACATCATGCGCGCCTATGACGTCTCATTCT
CATTGGGGGACGGCCTGCGCCCCGGCGCCATCGCGGACGCGAACGACGCGGCGCAGTTTGCAGAGCTGGAAACCCTCGGT
GAGCTGACGAAGATCGCCTGGGCCAAGGGCTGTCAGGTGATGATCGAAGGGCCCGGCCATGTGCCGATGCACAAGATCAA
GATCAATATGGACAAGCAGCTCAAAGCTTGCGGCGAGGCCCCATTCTACACGCTCGGGCCGCTCGTCACCGATATTGCGC
CGGGTTATGATCATATCACGTCGGGCATTGGCGCGGCGATGATCGGCTGGTTTGGCACGTCCATGCTCTGCTATGTGACG
CCCAAGGAGCATTTGGGGCTGCCCGACCGGAATGATGTGAAGGTTGGCGTGATCACCTACCGTATCGCGGCCCATGCCGC
CGACCTTGCCAAGGGCCACCCCGCCGCGCAGCTGCGCGACGATGCCCTCTCCCGCGCGCGGTTCGAGTTCCGCTGGGAAG
ACCAGTTCAATCTGGCGCTCGACCCCGAAACCGCGCGGGACTTCCACGACCAGACCCTGCCGAAAGACGCACATAAAGTG
GCCCATTTCTGCTCCATGTGCGGCCCGAAATTCTGCTCGATGAAAATCACCGCCGAAGTCCGCGACTACGCCGCCGGAAT
GTCCGAGAACGAACGTCTGGACCTGGAGAAACAGGCCGCCGAAGCCCGCAAGGGCATGGAGGAAAAGAGCCGCGAGTTCC
TGAACAAGGGAGGGGAGATTTACATACACGCTCCGAAGGACCGCCAAACGTGA

Protein sequence :
MNKPTKPGDFDAPKVTTGALPASRKVYSRPARDPDLAVPHREIDLHPSANEPAVRVYDTSGPYSDPTAEIDVEKGLPRHR
RDWLLARGGLEEYDGRDVKPEDNGGATGKYLAREFPVKHMPLRGLPGQMVTQYEFAKAGIITKEMVYVAERENLGRSQAL
ENARAQIDQGNSFGADIPEFITPEFVRDEIARGRAIIPANINHAELEPQIIGRNFLVKINANIGNSAVASSIEEEVEKMV
WATRWGADNVMDLSTGRNIHNTREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEVYRDTLIEQCEQGVDYFTIHAGVR
LAYIHLTAKRVCGIVSRGGSIMAKWMLAHHKESFLYDHFEDICDIMRAYDVSFSLGDGLRPGAIADANDAAQFAELETLG
ELTKIAWAKGCQVMIEGPGHVPMHKIKINMDKQLKACGEAPFYTLGPLVTDIAPGYDHITSGIGAAMIGWFGTSMLCYVT
PKEHLGLPDRNDVKVGVITYRIAAHAADLAKGHPAAQLRDDALSRARFEFRWEDQFNLALDPETARDFHDQTLPKDAHKV
AHFCSMCGPKFCSMKITAEVRDYAAGMSENERLDLEKQAAEARKGMEEKSREFLNKGGEIYIHAPKDRQT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 65
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 3e-174 64