Gene Information

Name : HNE_2188 (HNE_2188)
Accession : YP_760884.1
Strain : Hyphomonas neptunium ATCC 15444
Genome accession: NC_008358
Putative virulence/resistance : Virulence
Product : DNA-binding heavy metal response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2282460 - 2283143 bp
Length : 684 bp
Strand : +
Note : identified by similarity to SP:O31395; match to protein family HMM PF00072; match to protein family HMM PF00486; match to protein family HMM TIGR01387

DNA sequence : 
ATGAAGATTTTGATTGTTGAAGATGAGCCGAAAACGATTGCGTATCTGCAGCGCGGCCTCACTGAGCAGGGCTATGCCGT
TGATACCGCCGCGAACGGTGAAGACGGGCTGCATCTTGCGCTGACCGGCGAATATGACGCCATCGTGATGGACGTCATGA
TGCCAGGACTTGACGGGGTCTTGGTGCTTCAATCGTTGCGCATATCGAAAGATACACCTGTTATCTTCCTGACCGCCAGA
GACAAGGTCGATGACCGCCTGCGCGGACTGGGCGCGGGAGCTGACGACTATCTGGTGAAACCCTTCTCTTTTCTGGAGCT
GGTTGCACGGATTCAGGCAATCACGCGCCGCGGCCGGACCCGGGAGACCACCCTAATCCAGGTTGCCGATCTGCATATCG
ATCTGGTGTCGCGACGCGCCATCCGCGGCGCCCGGAGGCTCAACCTGACGGCGCGCGAGTTCTCCCTGCTGGCAGCCCTC
GCCCGCCGCCGCTCTCAGATCGTTTCCAAGACCGCTATTGCCGAACTCGTCTGGGATATCAATTTCGACACGAATACAAA
TGTGGTCGAAGTGGCCATCAAACGCCTGCGGAGCAAACTCGAAGAGCCAGGCGAAATCAGGCTCCTCCATACGGTGAGGG
GTATGGGATATGTGCTGGAGCTACGCGAGGAAGGCGGGCTATGA

Protein sequence : 
MKILIVEDEPKTIAYLQRGLTEQGYAVDTAANGEDGLHLALTGEYDAIVMDVMMPGLDGVLVLQSLRISKDTPVIFLTAR
DKVDDRLRGLGAGADDYLVKPFSFLELVARIQAITRRGRTRETTLIQVADLHIDLVSRRAIRGARRLNLTAREFSLLAAL
ARRRSQIVSKTAIAELVWDINFDTNTNVVEVAIKRLRSKLEEPGEIRLLHTVRGMGYVLELREEGGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 6e-53 53
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 7e-52 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator BAC0197 Protein 4e-61 57
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator BAC0125 Protein 5e-63 57
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator BAC0083 Protein 9e-60 55
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator BAC0638 Protein 9e-55 54
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator BAC0308 Protein 1e-56 51
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator BAC0111 Protein 6e-53 49
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator BAC0347 Protein 2e-48 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator VFG0596 Protein 2e-53 53
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator VFG1389 Protein 3e-41 49
HNE_2188 YP_760884.1 DNA-binding heavy metal response regulator VFG1390 Protein 2e-39 44