Gene Information

Name : Mmar10_2116 (Mmar10_2116)
Accession : YP_757346.1
Strain : Maricaulis maris MCS10
Genome accession: NC_008347
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 2302705 - 2305836 bp
Length : 3132 bp
Strand : +
Note : PFAM: acriflavin resistance protein; KEGG: sil:SPO0921 transporter, AcrB/AcrD/AcrF family

DNA sequence :
ATGAGCACCGCATCCACCCCGTCGAGCGCCCTTGCAAGACTGTCGATCGAAAAGCCCGTCCTGACCTGGATGGTCATCCT
GTTCTGCCTGCTCGGCGGGCTGGCCGGCTTCATGAATGTCGGCCGTCTGGAAGACCCGGCCTTTACCGTCAAGGAGGCCA
TCATTTTCACGGCCTATCCCGGCGCGACCGCGGAAGAGGTCGAACAGGAAGTCACCGAAGCGTTGGAAATCGCCATCCAG
CAGCTTGGTGAAGTCCACGAAATCCGGTCGGAATCCTCGCCCGGAATCTCGGAAATCCATGTCACGATCGACGACACGAT
CGACAGCGGCGACATGCCGGCCGTCTGGACCCGGCTGCGGGCCAAGATCAGGGACACGGTCGGCAGCCTGCCGCCCGGCG
CCGGCGCGCCCGTCGTTTATGATGATTTCGGCGATACCTACGGGATTTTCTATGCGGTCACCGCGGAAGGCTATTCCGAC
AGTCGCATCCGTGATGTGGCGCGCATGTTGCGGCGCGAATTGCTGACCGTCGAGGACGTCGCCAAGGTCGCCGTCGAGGG
CGAGCCGGACGAGCGCATCTATATCGAGATCCCGCAGGAAAACCTCGCCCGCCTGGGCCTGTCCTATGCCGATCTCCTCG
AAGATCTGGAACAGGAAAATGCCGTCGTCGCCGCCGGATCGGCGCCGCTGAATGACCGGCTCGTCCGGGTCGATATTCCC
CAGACGCTCGGCGGAACGGAAGCGATTTCCAACCTGCTGATCACGCCACGCGATAGCGACCAGGCGATCCGCCTGTCGGA
CATTGCCGAGGTCCGCCGCGACACGGTCGAGCGCCCGACGCAACTGATTTACCACAATAATGTCCGCGCCTTCACGATCG
GCGTGGCCGGCCTGCCAACAGCCAATATCGTCGATGTCGGCCATGCGGTCGAAGCGCGCCTGGCGGAGCTTGAGTCCAGC
CTGCCGCTGGGTGTCGAGCTGCATCCGATCTACCAGCAGCACCAGGTCGTCGATGATGCGATCAACAGCTTCCTGGTCAG
CCTTGCCCTGTCGATCGCCATCGTGATCGGCGTGCTGTGCATTTTCATGGGCTGGCGGGCCGGCCTGACCGTTGGCGCTG
TCCTTTTCCTGACCATCGCCGGCACGATCTTTTTCATGAGCCTGTTCTCGCTGGAGATGGAGCGCATCTCCCTGGGCGCA
TTGATCATCGCCATGGGCATGCTGGTCGACAATGCCATCGTGGTGACCGAGGGCATGCTGACCGGCGTCATGCGGGGCAA
GCCGCGCATGCAGGCGGCCGAAGAAGCCGTCGCCACCACGCAATGGCCGCTGCTGGGCGCCACTGTGATCGGCATCCTCG
CCTTTGCCGGGATCGGCCTGTCGCCGGATGCGACCGGCGAATTCCTGTTCTCCCTGTTCGCCGTAATCGCGATCTCGCTG
CTGCTGAGCTGGGTCATCGCTGTCACCGTCGTGCCGATGGTGGGCTTCCACCTCTTCTCCGCCCAGCGCGCCGCAGCGCA
GGCCGTCAGCGATCACAGCCATGATGAGGAGAGCCTGTACACCGGTCGCCTGTTCAATGGCTATCGCGGGCTTTTGAACC
TCGCCCTGTCACGGCGCTGGGTCGTGCTGGCCCTGCTGATCGTCATCACCTTTGTCTGCTATGCCGGCTTCGGGTCCGTC
CGCAACTCCTTCTTCCCGGCCACCAACACGCCGGTCTTCTACGTCAATGTCGAACTGCCCGAGGGCACCGACATCCTGAC
CACCGACGCCACCATGCGTGAGATTGGCAGTTTCGTTTCCGATCAACCGGAAACCACGGCCATCGATACCTTTGTCGGCG
CCGGCGCAACCCGCTTCATGCTGACCTACACCGCCGAACAGCCCAATACCGCCTATGGCCAGATCATCGTCTGGGCCCGC
GACCTTGAGTCCATACCGGACCTGGCCGACCGCATCCTGGCCCATGTCCGCGACACAGTCCCGGATGCCGAAATCCGCAC
CGACCGGATCGTCTTCGGCCCGCCCTCTGGTGCCAAGCTGGAAGCGCGTTTTTCGGGTCCGGACGCCGATATCCTGCGGG
AACTCGCCGAACAGGCGATGGCCGCCCTCGCAGCCGAGGCCGATGTCATCGACATCCGCACCGACTGGCGCAATCGCACC
CCGGTCCTGCGCCCGGTCATCATCGAGGAGACGGCGCAGACCATCGGTGTCACCCGTGAGAACATCGCCAATGCGTTGCG
CTTCGCCACGGACGGCAATCAGATCGGCGTCTATCGCGAAGGCGAGACCCTGATCCCGATCCTCGCCCGCGCACCGGAAG
CCGAACGCGCCGATCCGGCTTATCTGGGTGACCGCCTGGTGTGGAGCCCGCAACAGGCGGCCTATGTCCCGATCAGTCAG
ATCGTGTCCGAATTCGCGCTCGAATTCGAGGATGTGCTGATCCAACGGCGTGACCGGACCCGGACGATTTCGGTGCGGGC
CAATCCCCATGGCTGGGAAACCGCCGCGGAAGGCTTTGCCCGCTTCCAGCCGGTGCTCGAGGCCATTGACCTGCCGCGCG
GCTATTCGCTGGAATGGGGCGGCGAGTATGAAGCCTCGGCCGAAGCCAACGCCTCGCTGGGCGGACAGCTGCCGCTCACC
TTCATCGCCATGCTGACCATCTCCTTCCTGCTGTTCGCGACCATCCGCCAGCCGCTGATCATCTGGGCCGTTGTCCCAAT
GTCGGTGAACGGGGTGGTGATCGGTCTTCTGGCCACCAATGTCGCCTTCTCCTTCACCGCCCTTCTGGGCCTCTTGTCGC
TGTCCGGCATGCTGATCAAGAATGCGATCGTGCTGGTCGACGAGATCGACATGCGGATCCGCAGCGGGTCTGACCGGCTG
GTGGCGGTTCGCGATGGGTCGATCAGTCGTCTCCGGCCAGTCCTTCTGGCCGCCAGCACCACGATCCTCGGCATGACGCC
GCTGATCAGCGACGCCTTCTTCCAGGGCATGGCGGTGACCATCATCGGCGGGCTGACCTTCGCCACAGTGCTGACCATGA
TCGCCGTGCCGGTCCTGTACGCGCTCTTCTTCGGCATCAAACCGGAAAAACGTCGCAAGGATGACACGCTGCCAGAGCCC
GTCGAGGCTTGA

Protein sequence :
MSTASTPSSALARLSIEKPVLTWMVILFCLLGGLAGFMNVGRLEDPAFTVKEAIIFTAYPGATAEEVEQEVTEALEIAIQ
QLGEVHEIRSESSPGISEIHVTIDDTIDSGDMPAVWTRLRAKIRDTVGSLPPGAGAPVVYDDFGDTYGIFYAVTAEGYSD
SRIRDVARMLRRELLTVEDVAKVAVEGEPDERIYIEIPQENLARLGLSYADLLEDLEQENAVVAAGSAPLNDRLVRVDIP
QTLGGTEAISNLLITPRDSDQAIRLSDIAEVRRDTVERPTQLIYHNNVRAFTIGVAGLPTANIVDVGHAVEARLAELESS
LPLGVELHPIYQQHQVVDDAINSFLVSLALSIAIVIGVLCIFMGWRAGLTVGAVLFLTIAGTIFFMSLFSLEMERISLGA
LIIAMGMLVDNAIVVTEGMLTGVMRGKPRMQAAEEAVATTQWPLLGATVIGILAFAGIGLSPDATGEFLFSLFAVIAISL
LLSWVIAVTVVPMVGFHLFSAQRAAAQAVSDHSHDEESLYTGRLFNGYRGLLNLALSRRWVVLALLIVITFVCYAGFGSV
RNSFFPATNTPVFYVNVELPEGTDILTTDATMREIGSFVSDQPETTAIDTFVGAGATRFMLTYTAEQPNTAYGQIIVWAR
DLESIPDLADRILAHVRDTVPDAEIRTDRIVFGPPSGAKLEARFSGPDADILRELAEQAMAALAAEADVIDIRTDWRNRT
PVLRPVIIEETAQTIGVTRENIANALRFATDGNQIGVYREGETLIPILARAPEAERADPAYLGDRLVWSPQQAAYVPISQ
IVSEFALEFEDVLIQRRDRTRTISVRANPHGWETAAEGFARFQPVLEAIDLPRGYSLEWGGEYEASAEANASLGGQLPLT
FIAMLTISFLLFATIRQPLIIWAVVPMSVNGVVIGLLATNVAFSFTALLGLLSLSGMLIKNAIVLVDEIDMRIRSGSDRL
VAVRDGSISRLRPVLLAASTTILGMTPLISDAFFQGMAVTIIGGLTFATVLTMIAVPVLYALFFGIKPEKRRKDDTLPEP
VEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 2e-170 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mmar10_2116 YP_757346.1 acriflavin resistance protein BAC0428 Protein 0.0 45
Mmar10_2116 YP_757346.1 acriflavin resistance protein BAC0519 Protein 0.0 45
Mmar10_2116 YP_757346.1 acriflavin resistance protein BAC0526 Protein 0.0 44
Mmar10_2116 YP_757346.1 acriflavin resistance protein BAC0425 Protein 9e-171 42