Gene Information

Name : guaA (Mmar10_1184)
Accession : YP_756415.1
Strain : Maricaulis maris MCS10
Genome accession: NC_008347
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1298602 - 1300161 bp
Length : 1560 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCGATCAACACGACAAACTCCTCATCATCGATTTTGGCAGCCAGGTGACCCAGCTCATCGCCCGCCGCGTCCGCGA
GAGCGGGGTGTTCTGCGAGATCCACCCCTATAACCGCGCCGACGCCGCCTTCATCGATGCCTATGACCCCAAGGCGATCA
TCCTGTCGGGCTCGCCGCATTCCACCCATTGGGACAATTCCCCGCGCGCCGACGCGTCGGTCTTCACGCGCGGAATTCCC
GTCCTGGGGATCTGCTATGGCGAGCAGACCATGTGCGCCCAGCTGGGCGGCCGGGTCGAGGCCTCCGAGGAGCGCGAGTT
TGGCCGCGCCGACATCAAGCTGGTCGAGGACAGCCCGCTCTTTGCCGGCTTTGGTCCGGTCGGTCATGAAGAGCGCGTCT
GGATGAGCCATGGCGACCGTGTCGCGGCGCTGCCCGAGGGCTTCAAGGTCATCGCGACCTCGGGCAATGCGCCCTATGCC
GCCATTGCGGACGAGACCCGCAAATTCTACGGCGTGCAGTTTCATCCGGAAGTGGTTCACACACCGCGTGGCGCAGCCCT
GCTCGAAAATTTCACGCACAAGATTGCCGGCCTTACAGGTGACTGGTCGATGGCCAATTTCAAGGATGAGGCGATTGCCA
AGATCCGCGAACAGGTTGGCGACAAGCGCGTCCTGTGCGGCCTGTCCGGCGGCGTCGACAGCTCGGTCGCAGCCGTCCTG
CTGCATGAGGCGATCGGCGACCAGCTGGTCTGTGTCTTTGTCGATACCGGCCTGATGCGCCAGGGCGAGGCCGACGAGGT
CGTGACCCTGTTCCGCGAGCACTACAATATCCCGCTCGTCCATGCCGAGGCCGAGGACCTCTTCCTGACCGCCCTTAAGG
GCGTCGACGATCCGGAGAAGAAGCGCAAGATCATCGGCAGCCTCTTCATCGATGTCTTCGACGAGAAGGCCAAGGAGGCC
GGCGGCGCCGACTTCCTCGCCCAGGGCACGCTCTATCCCGACGTCATCGAAAGCGTCAGCTTTGATGGCGGCCCCTCCGT
CACCATCAAGTCGCACCATAATGTCGGCGGCCTGCCGGCCCGGATGAAGATGAAGCTGGTCGAGCCGCTGCGCGAGCTGT
TCAAGGACGAAGTCCGTGCGCTTGGCCGCGAGCTCGGCCTGCCGGACGCCTTTGTCGGTCGCCATCCCTTCCCGGGACCG
GGTCTCGCCATCCGCATCCCCGGCGCTGTCTCCAAGGAAAAGGCCGACATCCTGCGCAAGGCCGATGCGATCTATATCGA
GGAGATCAAGAAGGCCGGCCTCTATGACGAGATCTGGCAGGCTTTCTCGGTCCTGCTGCCGGTCAATACGGTCGGTGTGA
TGGGCGATGAACGCACCTACGACGCCGTCCTCGCCCTGCGCGCCGTCACCAGCGTCGACGGCATGACGGCGGACTACTAC
CCCTATGAGCACGACTTCCTCAGCCGCGTGGCGACGCGGATCATCAATGAAGTGCGCGGCGTGAACCGGGTGGTCTATGA
TGTGACGTCCAAGCCGCCGGGGACGATTGAGTGGGAGTAG

Protein sequence :
MTDQHDKLLIIDFGSQVTQLIARRVRESGVFCEIHPYNRADAAFIDAYDPKAIILSGSPHSTHWDNSPRADASVFTRGIP
VLGICYGEQTMCAQLGGRVEASEEREFGRADIKLVEDSPLFAGFGPVGHEERVWMSHGDRVAALPEGFKVIATSGNAPYA
AIADETRKFYGVQFHPEVVHTPRGAALLENFTHKIAGLTGDWSMANFKDEAIAKIREQVGDKRVLCGLSGGVDSSVAAVL
LHEAIGDQLVCVFVDTGLMRQGEADEVVTLFREHYNIPLVHAEAEDLFLTALKGVDDPEKKRKIIGSLFIDVFDEKAKEA
GGADFLAQGTLYPDVIESVSFDGGPSVTIKSHHNVGGLPARMKMKLVEPLRELFKDEVRALGRELGLPDAFVGRHPFPGP
GLAIRIPGAVSKEKADILRKADAIYIEEIKKAGLYDEIWQAFSVLLPVNTVGVMGDERTYDAVLALRAVTSVDGMTADYY
PYEHDFLSRVATRIINEVRGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-134 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-134 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-134 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-117 51