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Name : leuS (Swol_1599) Accession : YP_754271.1 Strain : Syntrophomonas wolfei Goettingen Genome accession: NC_008346 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1824396 - 1826870 bp Length : 2475 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGATAGAAAGTATGATTTTAAATCCATTGAAGCCAAATGGCAGGCTTACTGGGAAAATAAGCAGCTCTTTAAGGTAGA AGAAGACCCCGAAAAGCCCAAATATTATAATCTGGAGATGTTTCCCTACCCTTCCGGCCACCTGCACATGGGCCATGTAC GCAACTATGCCATCGGTGATGTGGTGGCGCGTTTCAAAAGCATGAACGGATTCAATGTCCTTCATCCCATGGGCTGGGAT GCTTTTGGCCTTCCCGCTGAAAATGCGGCCATTAAAAATGCTATTCACCCTGCTACCTGGACCTACTCTAATATCGAAAA CATGAAAAGACAGCTCAAGACCATGGGGATCAGCTATGATTGGGATCGGGAGCTGGCTACCTGCAAACCAGATTATTACA AATTTACCCAGTGGATGTTTTTAAAGCTCTACGAGAATAAGCTGGCCTATAAAAAGAAATCCGCCGTAAACTGGTGCCCT TCCTGCCAAACGGTTTTGGCCAATGAACAGGTGGTAGATGGGGCGTGCGAACGCTGTGAAGCTGTTATTGAAAAAAAACA ACTGGAACAGTGGTTTTTCAAAATAACTGACTATGCCCAACGGCTTTTGGATGATTTAGCCCTGCTGCCGGGCTGGCCGG AAAAAGTTAAGACCATGCAAAAAAACTGGATCGGCCGCAGCGAAGGCTGTGAATTTTCCCTGCATATTGAAGACAGTGAT GAAGTCCTCACTGTTTTTACCACGCGCCCAGATACGGTTTTTGGTGTCACCTACATGGTTTTGGCCCCGGAACATCCCCT GGTGGAAAAAATCTGCCACCCGGAGCAGGAAAAAGAAGTCAAGGCTTTTGTCAATAAAATGAAATATCTTAATGAAATGG CCCGCACCTCTACTGAAGCGGAAAAGGAAGGTGTTTTCACCGGAGCCTATGCCATCAACCCGATGGATGGGTCACGAATC CCGATTTGGATAGCCAACTATGTTTTAATGGACTATGGTACCGGGGCTATAATGGCCGTTCCTGCCCATGACCAGAGGGA TTTTGAATTTGCCCGCAAATATGATATACCGGTTAAAGTGGTAATAAAAGGTGAGGATACTCCCCTGGATGGAAATCTCC TGCAGGAATCCTACCCTGGTGACGGCCATATGGTAAATTCCGGAAACTTTGATGGTTTAACTGTGGAGGAAGGCCAAAAA GCAGTAATCAAATTCATGGAAGAGAAGGGAATCGGCCAGGGTACGGTCAATTACCGCTTGCGCGACTGGCTGATTTCACG GCAACGCTACTGGGGAGCCCCCATTCCTATTGTTTATTGCCCTGAATGCGGCCCGGTTGCAGTTCCCGAAGAAGAACTAC CCTTATACCTGCCCGAGGATATAGATTTTAAACCTTACGCAGAATCGCCTTTAAAGCATCTTGAGAGGTTTTACAAGACT ACATGCCCTTCTTGCGGAAAAGAAGCCCTGCGGGAAACTGATACCATGGATACCTTTGTCTGTTCCTCCTGGTACTTTGA CCGTTTTTGCAGTCCTCATGAGAGCAAGCAGCCTTTTAGCCGGGAAGCCGTGGATTACTGGATGCCGGTTGACCAGTATA TAGGCGGTGTGGAACACGCTATTTTACATCTTATGTATGCCCGTTTTTTCACCAAATTTCTTTTTGATATTAATGTTCTA TCATGTCAGGAACCCTTTACCCGCTTGCTCACCCAGGGTATGGTTTTAAAGGATAATGCCAAGATGTCCAAGTCCAAAGG AAATGTAGTTAGTCCGGAAGAGATAATCGACACCTATGGAGCTGACACTGCACGGCTCTTCATTCTTTTCGCTTCTCCTC CCGAGAGAGACCTGGAATGGAGTGAGCAGGGTGTAGAAGGTGCTTTTCGCTTCTTGAACCGAGTCTGGCGCTTGGTATCG GAATTAGCTGAGGGAATAAAAGATTTGCCCGCAGCCGAGCATTTTCCAGAACTGGACAGTGAAGCCAAGAACTTGCGCTT CAAAACTCACGCAACCATAAAGAAGGTTACTGAGGATATTGGAGAACGCTTTAACTTCAATACCGCTATCAGTGCTATTA TGGAGTTGTCGAATACCCTGGGAGCCTACAAGGGAATCAAAAAACCGAACTGGCCGGTAGTAAAAGAAGCGGTGGATAAT CTGCTGATTCTCTTAAGCCCGTTTTCACCCCATATCTGTGAAGAGCTGTGGCAGTTAACCGGGCACGCAGAGAGTATTTA CCTGCAGAAATGGCCGAAATATGATCCTGAAGCATTGCTTCAGGAAGAAATTGAAATCGTCCTGCAGATTAGCGGTAAAG TACGAGACCGGATAATGGTGCCGGTTGATGCCGGCCGGGAGGAATTGGAGAAAATAGCCCTGGATAATCCTAAAATTAGA GAATTGACCAGGGGTAAAGAGATAGTAAAGCTTATCGTAGTTCCTGGAAAGCTGGTCAATGTTGTGGCAAAATAA Protein sequence : MDRKYDFKSIEAKWQAYWENKQLFKVEEDPEKPKYYNLEMFPYPSGHLHMGHVRNYAIGDVVARFKSMNGFNVLHPMGWD AFGLPAENAAIKNAIHPATWTYSNIENMKRQLKTMGISYDWDRELATCKPDYYKFTQWMFLKLYENKLAYKKKSAVNWCP SCQTVLANEQVVDGACERCEAVIEKKQLEQWFFKITDYAQRLLDDLALLPGWPEKVKTMQKNWIGRSEGCEFSLHIEDSD EVLTVFTTRPDTVFGVTYMVLAPEHPLVEKICHPEQEKEVKAFVNKMKYLNEMARTSTEAEKEGVFTGAYAINPMDGSRI PIWIANYVLMDYGTGAIMAVPAHDQRDFEFARKYDIPVKVVIKGEDTPLDGNLLQESYPGDGHMVNSGNFDGLTVEEGQK AVIKFMEEKGIGQGTVNYRLRDWLISRQRYWGAPIPIVYCPECGPVAVPEEELPLYLPEDIDFKPYAESPLKHLERFYKT TCPSCGKEALRETDTMDTFVCSSWYFDRFCSPHESKQPFSREAVDYWMPVDQYIGGVEHAILHLMYARFFTKFLFDINVL SCQEPFTRLLTQGMVLKDNAKMSKSKGNVVSPEEIIDTYGADTARLFILFASPPERDLEWSEQGVEGAFRFLNRVWRLVS ELAEGIKDLPAAEHFPELDSEAKNLRFKTHATIKKVTEDIGERFNFNTAISAIMELSNTLGAYKGIKKPNWPVVKEAVDN LLILLSPFSPHICEELWQLTGHAESIYLQKWPKYDPEALLQEEIEIVLQISGKVRDRIMVPVDAGREELEKIALDNPKIR ELTRGKEIVKLIVVPGKLVNVVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 2e-172 | 45 |
