Gene Information

Name : leuS (Sfri_0705)
Accession : YP_749401.1
Strain : Shewanella frigidimarina NCIMB 400
Genome accession: NC_008345
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 829380 - 831998 bp
Length : 2619 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGGCGGCATGGCCGGAAATAGATTGATGCAAGAGCTATATAATCCCTCAGAAATTGAAGCCTTAGTGCAAAAGCACTG
GCACGAACATAAAACCTTTGAAGTTACTGAAGATGAAAGCAAAGAGAAATTCTATTGTCTTTCAATGTTTCCGTATCCAT
CAGGTCGTCTTCACATGGGCCACGTCCGTAACTACACAATAGGCGATGTAGTGGCACGATATCAACGTTTGCAAGGTAAA
AATGTTTTGCAACCGATTGGTTGGGACTCATTTGGTCTGCCTGCAGAAAATGCCGCGATCAATAATAAGGCGTCGCCGGC
ACCGTGGACATACGAAAATATCGACTACATGAAGAACCAACTCAAGCTATTGGGCTTTGGTTATGACTGGAGTCGTGAAA
TTGCTACCTGTACCCCTGAGTACTATCGTTGGGAACAATGGTTCTTCACTCAGTTGTATGCCAAAGGTTTAGTGTATAAA
AAAACCTCATCAGTAAACTGGTGTCCAAACGATGAAACCGTACTCGCAAACGAGCAAGTACAAGATGGTTGTTGCTGGCG
CTGTGATACTGAAGTGATCCAGAAAGAAATTCCTCAGTGGTTTATTAAAATCACTGATTACGCTGAAGAATTGCTTAACG
ACATCGACACGTTAGATGGCTGGCCTGAACAGGTTAAAGCCATGCAGCGTAACTGGATAGGTCGCAGTGAAGGGATTGAA
ATGACCTTTGCCGTTGCTGACAGTGATGCATCGTTTGATATCTACACCACTCGTCCTGATACCTTAATGGGCGTGACTTA
TGTTGCTATTGCAGCTGGTCACCCATTAGCTGAACAGTCTGCGCAAAATAACCCTGAATTAGCCGCATTTTTAGAAGAAT
GTAAAAATGCTGATACCACTGAAGCTGCGATGGCTTCGATGGAGAAAAAAGGCGTCGCGACAGGTTTACAAGCGATTCAT
CCTATTAGTGGCAAGTTAGTACCTATTTGGGTCGCTAACTTTGTATTGATGAATTACGGCACAGGTGCGGTAATGTCAGT
TCCAGCTCATGATCAACGCGATTATGAATTTGCGACTAAATACCAGCTTGCGATTGAAGCGGTCATTAAGCCAGTAGATG
GCGAAGTAGACGTTAGCAAAGAAGCTTACACCGAAAAAGGTGTGGTGTTTAATTCGGGCGATGCATTCCCTGAGCTAGAC
GGTTTAGACTTCCAAGCAGCTTTTGAAGCTATTGATGCTAGATTAACCGCAGAAGGTAAAGGCAAACGCCAAGTCAATTA
TCGTTTACGCGACTGGGGTGTTTCTCGTCAGCGTTACTGGGGTGCTCCTATCCCGATGGTGACCCTCGCCGATGGTACTG
TTGTGCCAACGCCTGAAGATCAACTGCCTGTTATTTTGCCAGAAGATGTGGTGATGGACGGTATTCAAAGTCCAATTAAA
GCCGATAAGGCTTGGGCCGAAACCACAGTCAACGGTCAGCCAGCAACACGCGAAACAGATACCTTTGATACCTTTATGGA
ATCATCTTGGTACTACGCACGTTACTGTAGCCCTCACGCAGACGAAATGTTAGATCCTGCTAAAGCTAACTACTGGTTAC
CAGTAGATCAGTACATTGGCGGTATCGAACATGCTTGTATGCATTTGTTGTATTTCCGCTTTTTCCATAAGTTGCTGCGT
GACGCAGGCTTAGTCAACAGTGATGAGCCCGCAAAGCAGTTACTGACTCAAGGCATGGTATTAGCAGATGCTTATTACTA
CACCAACGAAAAAGGCGCCCGAGTTTGGGTATCACCTTTAGAAGTGACTGTGGTAGAAAAAGACGACAAAGGCCGCATCA
TTAAAGCGATAGACAATCAAGGTCATGAACTGGTTTACACCGGCATGAGTAAGATGTCTAAATCGAAAAATAACGGTATC
GATCCACAAGTCATGGTTGAAAAATACGGTGCTGATACCGTACGTTTATTCATGATGTTTGCCTCGCCACCAGAATTAAC
CCTGGAATGGCAAGAGTCAGGCGTTGAAGGAGCACATCGCTTCATTAAACGTTTCTGGAAATTGGCTAGCGATCATGTTG
CTGCAGGTAAAACTGAAGCATTAGATACCAGCAAATTAAATGCCGATCAAAAAGCATTGCGCCGTGAATTACATAAGACC
ATTGCCAAAGTCAGCGATGACATTGCACGTCGTCAAATGTTTAACACCGCAGTAGCCTCAGTAATGGAACTAATGAACCA
TTTACTGAAAGCCTCACAAGAAACGGCTCAAGACCGAGCGTTACTTGCTGAAGCTTTGTCTGCTGTAACGCGTTTGCTTT
ACCCTATTGTTCCGCATATGACGTTTACGTTATGGAATGAGTTAGGTAACGAAGGCGACATTGAAGATAGCCGTTGGCCT
GAAGTCGATGAGTCTGCGTTAGTCGAAGACAGCAAGCTCATTGTGGTACAAGTAAACGGAAAGGTTCGCGCAAAAATTAC
TGTTGCTGCTGATGCATCAAAAGAAGATGTAGAAGCATTAGGCATGAGTGATGAGCACGTACAAAAACACACTGAAGGGT
TAACGGTTCGTAAAGTCATTTACGTGCCCGGCAAACTATTAAGTATTGTTGCTAACTAA

Protein sequence :
MGGMAGNRLMQELYNPSEIEALVQKHWHEHKTFEVTEDESKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARYQRLQGK
NVLQPIGWDSFGLPAENAAINNKASPAPWTYENIDYMKNQLKLLGFGYDWSREIATCTPEYYRWEQWFFTQLYAKGLVYK
KTSSVNWCPNDETVLANEQVQDGCCWRCDTEVIQKEIPQWFIKITDYAEELLNDIDTLDGWPEQVKAMQRNWIGRSEGIE
MTFAVADSDASFDIYTTRPDTLMGVTYVAIAAGHPLAEQSAQNNPELAAFLEECKNADTTEAAMASMEKKGVATGLQAIH
PISGKLVPIWVANFVLMNYGTGAVMSVPAHDQRDYEFATKYQLAIEAVIKPVDGEVDVSKEAYTEKGVVFNSGDAFPELD
GLDFQAAFEAIDARLTAEGKGKRQVNYRLRDWGVSRQRYWGAPIPMVTLADGTVVPTPEDQLPVILPEDVVMDGIQSPIK
ADKAWAETTVNGQPATRETDTFDTFMESSWYYARYCSPHADEMLDPAKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLR
DAGLVNSDEPAKQLLTQGMVLADAYYYTNEKGARVWVSPLEVTVVEKDDKGRIIKAIDNQGHELVYTGMSKMSKSKNNGI
DPQVMVEKYGADTVRLFMMFASPPELTLEWQESGVEGAHRFIKRFWKLASDHVAAGKTEALDTSKLNADQKALRRELHKT
IAKVSDDIARRQMFNTAVASVMELMNHLLKASQETAQDRALLAEALSAVTRLLYPIVPHMTFTLWNELGNEGDIEDSRWP
EVDESALVEDSKLIVVQVNGKVRAKITVAADASKEDVEALGMSDEHVQKHTEGLTVRKVIYVPGKLLSIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 5e-158 42