Gene Information

Name : hemC (Sfri_0440)
Accession : YP_749140.1
Strain : Shewanella frigidimarina NCIMB 400
Genome accession: NC_008345
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 504270 - 505199 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCTGAAAATATAATTCGTATCGCAACACGTAAAAGTCCACTTGCAATGTGGCAAGCTGAATTTGTTAAAGCTGAGCT
TGAGCGCATTCATCCTGGGCTTACGGTTGAGCTATTGCCAATGAGTACTAAAGGTGATGTCATTTTAGATACTCCTTTAG
CTAAAATCGGTGGCAAAGGCTTGTTTGTTAAAGAGCTGGAAGTTGCCATGCTTGAAAATCGCGCCGATATTGCTGTGCAT
TCCATGAAAGACTTGCCGGTAGAGTTTCCAGAAGGTTTGGGCTTACAAGTGATTTGTGAACGTGAAGACCCGCGTGATGC
ATTTGTGTCAAACAATTATAAATCTATCAGCGAATTACCTCAGGGCGCTGTGGTAGGTACATCAAGTTTACGCCGTCAGT
GCCAAATTAGAGCTGCTCGCCCTGATTTAGTTATCAAAGATTTACGCGGAAATGTCGGTACTCGTTTAGCCAAGCTAGAC
AGTGGTGACTATGATGCGATTATTTTAGCGGCCGCCGGATTAATTCGCTTAAAGCTAAACGAACGTATCGCTAACTTTAT
TTCTGCCGAAGAATCACTGCCAGCCAATGGCCAAGGTGCGGTAGGAATTGAGTGCCGTACTGATGATGCGCGAGTTAAAG
CGTTATTAGCGCCACTAGAACATTTAGAAACCCGTTATAGAGTGCTTGCTGAACGAGCAATGAATACTCGTTTAGAAGGC
GGATGCCAAGTTCCTATTGGTGCTTTTGCTGAAATAAACGGTGATAATTTAACTCTACGTGGTTTAGTTGGTAATCCTGA
TGGCAGCCAAATCATTATAGGCACTGTCTCGGGTTCTAAGACCGATGCGGTTGCACTTGGGGAATCGCTTGCAGAGGATT
TACTGAGTCGCGGTGCTAAAACTATTTTAGACGCTGTGTATGCCAGTTAA

Protein sequence :
MSENIIRIATRKSPLAMWQAEFVKAELERIHPGLTVELLPMSTKGDVILDTPLAKIGGKGLFVKELEVAMLENRADIAVH
SMKDLPVEFPEGLGLQVICEREDPRDAFVSNNYKSISELPQGAVVGTSSLRRQCQIRAARPDLVIKDLRGNVGTRLAKLD
SGDYDAIILAAAGLIRLKLNERIANFISAEESLPANGQGAVGIECRTDDARVKALLAPLEHLETRYRVLAERAMNTRLEG
GCQVPIGAFAEINGDNLTLRGLVGNPDGSQIIIGTVSGSKTDAVALGESLAEDLLSRGAKTILDAVYAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-74 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-74 61