Gene Information

Name : Sfri_3488 (Sfri_3488)
Accession : YP_752155.1
Strain : Shewanella frigidimarina NCIMB 400
Genome accession: NC_008345
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 4151239 - 4152897 bp
Length : 1659 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidor

DNA sequence : 
ATGATTTTATTATCCATACGCTTATCCATACAAGGGATGAGCTGCCCAAGCTCCGTCGAACACATTAAAGAGGCGCTCGA
TGCCGTTGAAGGCGTCATTAAAACTGAGGTGTCTTATGCAAAAGCCCTAGCTGTGATCACCACAAGAGATGGTGTCAATG
TAGCAGAACTGATCCTAGCGATTAATGCCTTAGGCTACGTTGCAACAGAGCTTAAAGACACGACAAGGTGTGGCGACACT
GACCAGCAAGAAGACATTAGCCCTCAGCAACGGGTCGCCATCATAGGCAGCGGTTCTGGCGCTTTTGCCTGCGCCATCAA
GGCAGCGGAGCGTGGCGCACAGGTTACCATTATTGAAGCAAGCGAGGTGATCGGCGGCTGTTGTGTCAATGTTGGCTGTG
TGCCGTCCAAAATTTTAATTCGAGCGGCGCAATTGGCTCAGCAACAGCGAAGCAACCCGTTTGCAGGACTGGAAAATCAT
GCCCCAGAACTGAGTCGAGCGCGCTTATCCGAGCAGCAGACCGCGCGGGTGGAAGAATTGCGGGCAGCCAAATACCAGAA
TATTCTAGACAATAATCCCGCACTGAGTTTAATTAAAGGGTTTGCACGATTTAACGATGCCAATACCTTAATCATCCGTA
AAGTCGATGGTTCAGAGCTAGTGCTGCATGCCGATAAAATATTAATTGCCACCGGTTCGACGCCGACGATCCCGCCGATT
GATGGTCTTGCCGGCACCCCTTACTGGACATCCACAGAAGCATTATTTGCCAAAGCGCTGCCACAACATCTGATCGTGAT
TGGCTCCTCTGTGGTCGCGTTGGAGATAGCACAAGCTTATCGCCGCTTAGGTAGCGAGGTGACGGTATTGGCGCGGCATT
CATTACTGTATGCAGAAGACCCCTTGCTAGGTGAGAAACTTAGCGAATGTTTTGAAAAAGAAGGCATTAACGTGTTGAAT
CACACTCAGGCGGCAAGCGTTTCATATCAAGGAGAACAATTTACGCTGGAAACCAATGCGGGAACGTTAATTGGTGATCA
ACTGTTGATCAGTACCGGGCGTAATGCCAATACCAGCCAACTTAATCTTGCCGCAATCGGTGTTAAAACCAACCAGGGCG
GTGAGGTTATCGTCAATGAACGAATGGAGACCAATATTTCCGGCATTTATGCCGCCGGAGACTGTTCCAATATGCCGCAA
TTTGTCTATGTTGCTGCCGCAGCTGGCAGTCGTGCTGCTGTGAATATGATAGGTGGCGACGCCAAACTGGATCTCACCAC
TATGCCCGCGGTGATTTTTACCGATCCGCAAGTCGCCACTGTGGGTTTAACCGAAGTACAGGCCAAGGCGCAAGATATTG
AGACGGACAGTCGAGTCTTGGGCATGGAAAATGTGCCACGAGCCCTGGCCAACTTCGAGACCGACGGCTTCATTAAATTA
GTGGCAGAAAAGAAAACCGGTCGAATTATCGGAGCGCAAATATTGGCGCATGAAGGCGGTGAAATAATTCAGAGTGCAGC
ATTGGCCATTCGCAATCGCATGACAGTCACTGAGCTAGCGGATCAACTCTTCCCCTACCTGACCATGGTGGAAGGACTAA
AACTCTGCGCGCAGACCTTTAACAAGGATGTTAAAGCACTCTCCTGCTGCGCCGGGTAA

Protein sequence : 
MILLSIRLSIQGMSCPSSVEHIKEALDAVEGVIKTEVSYAKALAVITTRDGVNVAELILAINALGYVATELKDTTRCGDT
DQQEDISPQQRVAIIGSGSGAFACAIKAAERGAQVTIIEASEVIGGCCVNVGCVPSKILIRAAQLAQQQRSNPFAGLENH
APELSRARLSEQQTARVEELRAAKYQNILDNNPALSLIKGFARFNDANTLIIRKVDGSELVLHADKILIATGSTPTIPPI
DGLAGTPYWTSTEALFAKALPQHLIVIGSSVVALEIAQAYRRLGSEVTVLARHSLLYAEDPLLGEKLSECFEKEGINVLN
HTQAASVSYQGEQFTLETNAGTLIGDQLLISTGRNANTSQLNLAAIGVKTNQGGEVIVNERMETNISGIYAAGDCSNMPQ
FVYVAAAAGSRAAVNMIGGDAKLDLTTMPAVIFTDPQVATVGLTEVQAKAQDIETDSRVLGMENVPRALANFETDGFIKL
VAEKKTGRIIGAQILAHEGGEIIQSAALAIRNRMTVTELADQLFPYLTMVEGLKLCAQTFNKDVKALSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-126 56
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-126 56
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-126 56
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 7e-126 56
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 4e-129 56
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-126 56
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 1e-124 55
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 1e-124 55
merA AFG30120.1 MerA Not tested PAGI-2 Protein 1e-124 55
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 5e-125 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfri_3488 YP_752155.1 putative mercuric reductase BAC0652 Protein 2e-127 55
Sfri_3488 YP_752155.1 putative mercuric reductase BAC0653 Protein 2e-126 55
Sfri_3488 YP_752155.1 putative mercuric reductase BAC0650 Protein 2e-122 54