Gene Information

Name : Sfri_3462 (Sfri_3462)
Accession : YP_752132.1
Strain : Shewanella frigidimarina NCIMB 400
Genome accession: NC_008345
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 4116070 - 4118475 bp
Length : 2406 bp
Strand : +
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: pfl:PF

DNA sequence :
ATGAGCGAATGCGCTTCAAAGGGGTGTGGCTGCACGACTGAGCCGATCATCCAACCCACGGCACCGGCCCCGCTGGCAAC
CGGATCGGCTCAAGCGGTGTACCGCATCGAGAACATGGATTGCCCGACCGAAGAGGCGCTGATCCGAAGCAAACTGGCCG
GTCTGGCGGGGGTGGCGGGTCTTGAATTCAACCTGATGCAACGTACCTTGGCCGTGCGACACGAATTGCCTTCGTTGTCT
CCCGTCGAGCAGGCGCTGAAGGCCATCGGCATGCAAGCTGTGCGCATGGATCAGGCGTCGGCCGAGCAGACGACCAAGCT
GTCCATTGCCAAGATGGATTGCCCGACCGAAGAGACGTTGATCCGCAACAAGCTCGGCACCGTGGCCGGTGTTGCTGATC
TCGATTTCAACCTGATGCAGCGCACGCTGTCGGTACGCCATGCGAACCAGGTTCTGCCAGACGTGCTCGTGGCACTGCAA
GCGCTTGGATTCGAGGCGCAGGTCGTGGACACGGCAGAGGTCGCATCTCCATCCGCCGCCCCTGTGACCACGCCGACCAA
CTGGTGGCCGCTGGGCATCTCCTTGGTCACTGCATCGGCGGCCGAGGCGGTCTACTGGCTCCACAACGGCAATCACTGGT
CGGTTGTCGTTCTGGCGCTTGTCGCGGTCTTCACGGGTGGCCTCTCCACCTACAAGAAGGGGTGGATTGCGCTCAAGAAC
CGTAATCTCAACATGAACGCCCTCATGTCGATTGCGGTCACGGGTGCCATGTTGATCGGCCACTGGCCCGAAGCGGCAAT
GGTGATGGTACTGTTCGCGCTGGCCGAGGTAATCGAAGCCAAATCGCTGGATCGCGCTCGTAACGCTATCCGTGGCCTGC
TCGACCTGACCCCGGAACAGGCCACGGTACAGCAGGCTGACGGCACATGGCGCGAGGTGGGCGCCAAGCAAATCACCATC
GGCGCCCGCGTCCGGGTCAAACCAGGTGAGCGCATCGCCCTTGATGGTGAGGTGCTGGAAGGCCGCTCTGCCGTCAACCA
AGCCCCGATCACGGGTGAAAGCCTCCCGGTCGAAAAATCCCCCGGTGATTCGGTGTTCGCTGGCACGATCAACGAATCCG
GCTCGTTCGAGTACCGCGTCACCGCCTTGGCCAACAACTCCACTTTGGCCCGGATCATTCACGCGGTAGAGGCTGCGCAA
GGTAGTCGTGCGCCGACTCAGCGTTTTGTCGATCAGTTCGCCCGCTGGTACACCCCCGTTGTATTCGGCGTTGCCATCGC
CGTCGCGTTGTTGCCGCCGCTGTTCATGGGTGCGGCATGGCTCGACTGGATCTACCGTGCATTGGTTCTGCTGGTGGTCG
CCTGCCCGTGCGCACTGGTGATCTCTACACCGGTCAGCATCGTCAGCGGCCTGGCCGCCGCCGCCCGCCACGGCATTCTC
ATCAAAGGTGGCGTCTATCTGGAAGAAGGCCGCAAGCTGCGCTGGCTGGCTCTGGACAAGACCGGCACGATCACGCACGG
CAAGCCCGCACAGACCGACTTTGTCACATGGGGCAATGCACTCGCCTCGGACAGCCGCAGCATCGCTGCCAGTCTGGCGG
CCCGCTCGGACCATCCTGTATCCAAGGCGGTGGCACAGGCCGCGCAGACGGACGGGGTTGCCTTGCTCGACGTGGCCGAA
TTCAACGCGCTGCCCGGTCGGGGTGTGCAGGGCCAAATCAACGGTGAAACCTACCATCTTGGCAACCAGCGGATGCTAGA
AGAGCTGGGGCAGCGTACTCCCGAGCTGGAACAGCGCATCGCGGCGCTGGAAACCATGGGTAAAACTGTCGTGATGTTGG
TCAGCGCAAAAGGGGTTCATGCCTTATTTGCCGTAGCGGACACCATCAAGGAAAGCAGCAGGAGCGCCATTGCCGAGCTT
CATGCACTGGGCATCAACACCATGATGCTGACCGGCGACAACCCCCACACGGCACAGGCCATTGCCGCACAAGCCGGGAT
CGACCGTGCGCAAGGCAATCTGCTCCCAGACGACAAACTGCGCGAAGTTGAGCTACTGGCCATAAAGGGCAAGGTCGGCA
TGGTCGGTGATGGCATCAACGATGCCCCGGCCTTGGCGCGTGCGGACATCGGCTTTGCCATGGGAGCGGCTGGCACAGAT
ACCGCCATCGAGACCGCTGACGTGGCCCTGATGGACGACAACCTGGGCAAGATTCCGACCTTCGTGCGCCTGTCGCGTGC
GACGGCGCAGGTGCTGATGCAAAACATTGTGCTGGCCCTTGGCATCAAGGCAGTATTTCTGGTGCTGACCTTCACGGGTC
AAGCGACCATGTGGATGGCGGTGTTTGCTGATATGGGGGCCAGCTTGCTCGTCGTTGGCAATGGCTTGAGGCTGTTGCGC
AAATGA

Protein sequence :
MSECASKGCGCTTEPIIQPTAPAPLATGSAQAVYRIENMDCPTEEALIRSKLAGLAGVAGLEFNLMQRTLAVRHELPSLS
PVEQALKAIGMQAVRMDQASAEQTTKLSIAKMDCPTEETLIRNKLGTVAGVADLDFNLMQRTLSVRHANQVLPDVLVALQ
ALGFEAQVVDTAEVASPSAAPVTTPTNWWPLGISLVTASAAEAVYWLHNGNHWSVVVLALVAVFTGGLSTYKKGWIALKN
RNLNMNALMSIAVTGAMLIGHWPEAAMVMVLFALAEVIEAKSLDRARNAIRGLLDLTPEQATVQQADGTWREVGAKQITI
GARVRVKPGERIALDGEVLEGRSAVNQAPITGESLPVEKSPGDSVFAGTINESGSFEYRVTALANNSTLARIIHAVEAAQ
GSRAPTQRFVDQFARWYTPVVFGVAIAVALLPPLFMGAAWLDWIYRALVLLVVACPCALVISTPVSIVSGLAAAARHGIL
IKGGVYLEEGRKLRWLALDKTGTITHGKPAQTDFVTWGNALASDSRSIAASLAARSDHPVSKAVAQAAQTDGVALLDVAE
FNALPGRGVQGQINGETYHLGNQRMLEELGQRTPELEQRIAALETMGKTVVMLVSAKGVHALFAVADTIKESSRSAIAEL
HALGINTMMLTGDNPHTAQAIAAQAGIDRAQGNLLPDDKLREVELLAIKGKVGMVGDGINDAPALARADIGFAMGAAGTD
TAIETADVALMDDNLGKIPTFVRLSRATAQVLMQNIVLALGIKAVFLVLTFTGQATMWMAVFADMGASLLVVGNGLRLLR
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 69
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-114 46
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-114 46
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 4e-112 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfri_3462 YP_752132.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 76
Sfri_3462 YP_752132.1 heavy metal translocating P-type ATPase BAC0455 Protein 1e-89 42
Sfri_3462 YP_752132.1 heavy metal translocating P-type ATPase BAC0100 Protein 1e-60 42