Gene Information

Name : alr (Sfri_3345)
Accession : YP_752020.1
Strain : Shewanella frigidimarina NCIMB 400
Genome accession: NC_008345
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 3992551 - 3993669 bp
Length : 1119 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
TTGAAACCTTTTCCTCGTGCAGAAATCAGTCGTTACGCATTGCAAAGTAACTTGGCACAACTGCGCCTTATTGCGCCCAA
TAGTAAAATTATGGCAGTGGTTAAAGCCAATGGTTATGGCCATGGATTATTAAATGTTGCTGAATGTGTTGGCTTATTAA
ATTATGTAGAAAGCGTCTGCAAGTATCATGGCGGCGCAGATGGTTTTGGATTAGCAAGGCTTGAAGAAGCGTTGCAACTC
AGAGAAGGCGGTGTAAAAGGTAAGCTTTTATTATTAGAAGGTTTCTTCCGTCAGTCTGATTTACCCACACTGGTTAGCCA
CAATATTGATACTGTGGTTCATCATGAATCGCAATTGCAAATGCTTGAAACTATCGCGCTAGATAAGCCTGTCACCGTAT
GGATAAAAATTGATACTGGTATGCATCGTATTGGCTTTAGTCTTGAACAATTCAACAGTATTTATCAGCGCTTGCTGGCT
TGTCCGCAAGTGGCTAAACCGATTCATTTAATGACCCACTTTGCATGCGCCGACGAACCCGATAATCCTCTCACTCAAAC
GCAAATGAATGCCTTTGAGCAACAGGTTAGCGGCTTAGAAGGCGATCGCACCTTAGCAAATTCTGCAGGTACCTTATTTT
GGCCAACAAGCCAAGCCGACTGGGTAAGACCCGGCATTGCGCTTTATGGTGTATCTCCAGTTGTGGGTGATCGAGGCGTT
AATCATCGATTAATTCCAGCGATGGAGTTAGTCTCCAATTTAATCGCGGTGCGCGAGCATAAAGCCGGTGATAGTGTCGG
TTATGGTGCATCTTGGACCGCTAAAAAAGACACTCGTTTAGGGGTTGTTGCCATTGGTTATGGTGATGGTTACCCACGTA
ATGCGCCAGAAGGTACACCGGTGTGGATTAACGGCCGCAGAGTACCGATAGTCGGTCGAGTGTCTATGGACATGTTAACC
GTAGATTTAGGTGCTGATGCACAAGATAACGTCGGCGATAGCGTTCAACTGTGGGGCAAAGCACTTGCAGTAGAAGAAGT
GGCCGAGCACATTGGCACCATAGCTTATGAGTTAGTCACTAAGCTTACGCCGCGCGTGGTAGTTGAATTGCTCGATTGA

Protein sequence :
MKPFPRAEISRYALQSNLAQLRLIAPNSKIMAVVKANGYGHGLLNVAECVGLLNYVESVCKYHGGADGFGLARLEEALQL
REGGVKGKLLLLEGFFRQSDLPTLVSHNIDTVVHHESQLQMLETIALDKPVTVWIKIDTGMHRIGFSLEQFNSIYQRLLA
CPQVAKPIHLMTHFACADEPDNPLTQTQMNAFEQQVSGLEGDRTLANSAGTLFWPTSQADWVRPGIALYGVSPVVGDRGV
NHRLIPAMELVSNLIAVREHKAGDSVGYGASWTAKKDTRLGVVAIGYGDGYPRNAPEGTPVWINGRRVPIVGRVSMDMLT
VDLGADAQDNVGDSVQLWGKALAVEEVAEHIGTIAYELVTKLTPRVVVELLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 9e-50 44