Gene Information

Name : guaA (Sfri_1138)
Accession : YP_749829.1
Strain : Shewanella frigidimarina NCIMB 400
Genome accession: NC_008345
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1339029 - 1340606 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGTAATATTCACGATCATAAGATTCTAATCCTCGATTTTGGTTCTCAGTACACTCAACTTATTGCGCGTCGTATCCG
TGAAATTGGTGTGTATTGTGAGTTATGGGCGTGGGATGTGAGCGAAGCGCAAATTCGTGAGTTTGCCCCAAATGGTATTA
TTTTGGCTGGTGGCCCTGAAAGTGTCACTGCAGACAATTCACCACGTGCTCCAGAGTATGTGTTTAATGCTGGTGTGCCT
GTATTGGGTATTTGTTACGGCATGCAAACCATGTCAGAACAGCTTGGTGGCAAAGTGATTCAAGGCGTGGGTGAAGGTGA
GTTTGGTTACGCACAAATTGAATTACAAACCACATCTGCTTTGTTTAAAAGCATTGAAGATGCAGTAAGCGCAGAAGGCA
AACCTTTGCTCGATGTGTGGATGAGCCACGGTGATAAAGTGTCTGCTATCCCTGACGGTTTTGTGACGGTAGCGAAAACG
GCAACTTGTCCGTTTGCCGCTATGGCCAATGAAGAGAAAGGTTTTTACGGCGTACAGTTCCACCCTGAAGTGACTCACAC
TCGCCAAGGTCAGCGTATGCTAGAGCATTTCGCGTTAGACATTTGTGGCTGTAAAGCCAATTGGAAGCCATCATCAATTA
TTGAAGATGCTATTGAGCGTTTAAAAAAGCAAATTGGTGATGACGAAGTTATTCTGGGTTTATCTGGCGGGGTAGATTCA
TCGGTTGTGGCGATGCTATTACATCGGGCGATTGGCGATAAACTAACGTGTGTATTTGTTGATAACGGTTTACTGCGTTT
GAACGAAGCCGAGCAAGTATTAGAAATGTTTGGCGATCATTTTGGACTCAATATTGTTCACGTTGATGCTGAAAACCGTT
TCTTAGATGCAATGGCTGGCGAAGCAGAACCTGAAGCGAAGCGTAAAATCATTGGTCGTGTGTTTGTCGAAATTTTTGAT
GAAGAATCAAAAAAATGCGCGAATGCTAAATGGCTAGCCCAAGGCACTATTTATCCTGATGTGATTGAATCAGCGGGCAG
TGCAACCGGTAAAGCACATGTGATTAAGTCGCACCACAATGTTGGCGGTTTACCTGCCGATATGAAGATGGGTTTAGTTG
AACCACTACGTGAGTTATTTAAAGATGAAGTGCGTAAAATTGGTTTAGAGTTAGGCCTGCCTTACAACATGCTTTATCGT
CATCCGTTCCCAGGACCAGGTTTAGGTGTTCGTGTACTTGGCGAAGTGAAAAAAGAATATTGTGATTTACTGCGAAGTGC
AGACGCTATCTTTATTGAAGAGCTACACAAAGCTGATTTGTATAATAAAGTGAGCCAAGCCTTTACCGTTTTCTTACCCG
TTCGTTCGGTAGGTGTAATGGGTGATGGTCGTAAGTATGATTGGGTTGTATCGCTACGTGCGGTAGAAACTATCGACTTT
ATGACCGCACATTGGGCACATTTGCCGTATGATTTCTTAGGCCGCGTTTCTAACCGTATTATCAATGAAGTCGATGGTAT
TTCTCGTGTGGTTTATGATATTTCAGGTAAGCCGCCTGCAACAATTGAATGGGAATAA

Protein sequence :
MSNIHDHKILILDFGSQYTQLIARRIREIGVYCELWAWDVSEAQIREFAPNGIILAGGPESVTADNSPRAPEYVFNAGVP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIELQTTSALFKSIEDAVSAEGKPLLDVWMSHGDKVSAIPDGFVTVAKT
ATCPFAAMANEEKGFYGVQFHPEVTHTRQGQRMLEHFALDICGCKANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDS
SVVAMLLHRAIGDKLTCVFVDNGLLRLNEAEQVLEMFGDHFGLNIVHVDAENRFLDAMAGEAEPEAKRKIIGRVFVEIFD
EESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPADMKMGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRSADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-124 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-124 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-124 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-109 47