Gene Information

Name : lysS (Neut_0872)
Accession : YP_747100.1
Strain : Nitrosomonas eutropha C91
Genome accession: NC_008344
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 892152 - 893750 bp
Length : 1599 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCGGCAGCGGCTCCAGGATGTCCGTGCCGCTTGGTACGATACAGAGAGATTTTATACCAATAAAAATTACATAAAATT
TGGAATAGATATGACCCAGGAAGATACATCCGGTATTTCCCAGGATGAAAACAGCCTTATTGCAGAGCGTTATTCTAAAT
TGACTGCATTGCGCCAGATCGGCAATGCTTTTCCGAATGATTATCGTCGGGATAGCCTGGCTCGTGACCTGCATGAAAAG
TATGATAATGACTCAAGAGAAGAACTGGAAAGTGGGCAGGTTAAAGTAAAAGTTGCAGGACGCATGTTGTTTAAGCGTGT
AATGGGAAAGGCAAGCTTTGCAACGATCCAGGATATGAGCGGGCGGATACAGCTCTATATCTCCAATGATCATACCGGAG
AATCCGCTCACGAAGCATTCAGGCATTATGATCTGGGGGATATTCTCGGCGCGGAAGGTATTTTGTTCAAAACCAGGACG
GATGAATTGTCATTACGGGTTACCCGACTTCGTCTTCTGACTAAATCCTTGCGCCCGCTACCGGAGAAATTTCATGGCCT
TATCGATCAGGAACAGAAATACCGGCGACGTTACCTTGATCTGATTACAAATGAAGAAACACGCAAGGTATTCCTGGTTC
GCTCAAAAATTATTCAGGCAGTACGTGAATTTCTGGTTAACCGGGGCTATCTTGAAGTTGAAACGCCGATGATGCACTCT
ATTCCAGGAGGGGCTACTGCTCGACCTTTTATTACGCATCATAATGCATTGGATATGTCACTGTATCTGCGTATCGCACC
GGAACTTTACCTGAAGCGGTTGGTAGTGGGTGGTATGGAAAAAGTTTTTGAGATTAACCGTAATTTCAGGAATGAAGGTA
TATCCACTCGCCATAATCCGGAATTCACCATGCTGGAGTTTTATGAGGCTTATCAAGATCATCATTACCTGATGGATCTG
ACGGAATCCATGCTGCGTGAAGTTGCGCTGAAGGTGTTAGGAACCACTCGCATTGTCTATCAGCAGCGCGAAATGGATCT
TGCCCGGCCTTTTGCCCGGTTGACTGTCATGCAGGCCATCCTAAAATACCACCCTGAAAATTCCGAAGCACAACTTAACA
ACAGGGATGATTTGATCAAAATTTTGCAGGCAAAGGGAATCGGATTCAATCCGGACAGTGGAATCGGCGGACTGCAATTG
GCCTTGTTTGATGAAACAACCGAACATTTGCTGTTTGAACCCGTATTTATCGTTGATTATCCGGCCGAGGTATCGCCTTT
GGCACGCCGCAATGATCAAAATCCGGAGATTACGGATCGTTTTGAGCTTTATATTGCCGGGCGGGAAATTGCGAACGGCT
TTTCCGAGCTAAATGATCCTGAAGATCAGGCCAGTCGTTTCCTTGAACAGGCCAGGGCTAAAGAGGCAGGTGATATGGAA
GCGATGCACTATGACGCTGACTATATCCAGGCACTGGAATACGGATTGCCGCCAACGGCAGGTGAGGGAATCGGTATCGA
TCGGCTAGTAATGTTGCTGACAGATTCTCCAAGCATCCGCGATGTTATTCTGTTTCCGCAGTTACGCAAGGAAGACTAG

Protein sequence :
MRQRLQDVRAAWYDTERFYTNKNYIKFGIDMTQEDTSGISQDENSLIAERYSKLTALRQIGNAFPNDYRRDSLARDLHEK
YDNDSREELESGQVKVKVAGRMLFKRVMGKASFATIQDMSGRIQLYISNDHTGESAHEAFRHYDLGDILGAEGILFKTRT
DELSLRVTRLRLLTKSLRPLPEKFHGLIDQEQKYRRRYLDLITNEETRKVFLVRSKIIQAVREFLVNRGYLEVETPMMHS
IPGGATARPFITHHNALDMSLYLRIAPELYLKRLVVGGMEKVFEINRNFRNEGISTRHNPEFTMLEFYEAYQDHHYLMDL
TESMLREVALKVLGTTRIVYQQREMDLARPFARLTVMQAILKYHPENSEAQLNNRDDLIKILQAKGIGFNPDSGIGGLQL
ALFDETTEHLLFEPVFIVDYPAEVSPLARRNDQNPEITDRFELYIAGREIANGFSELNDPEDQASRFLEQARAKEAGDME
AMHYDADYIQALEYGLPPTAGEGIGIDRLVMLLTDSPSIRDVILFPQLRKED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 8e-122 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_747100.1 lysyl-tRNA synthetase VFG1668 Protein 4e-122 55