Gene Information

Name : murD (Neut_0248)
Accession : YP_746497.1
Strain : Nitrosomonas eutropha C91
Genome accession: NC_008344
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 261326 - 262738 bp
Length : 1413 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAATTACGCCGACAAAAAAATATTGGTTCTGGGTATGGGTAAAACCGGCATCTCCATGGTCAAGTGGCTTTCCCGTGC
CGGAGCTCGGGTGTCCGTAGCCGATACACGTACCACCCCGCCGAATCTTGAGCTGCTGAGTCAGATAGTGCCGCTTGAAA
CGATTTTCTGTGGTCCATTCAAGGCAGAGCTGTTCAAGGACATTGATGCAATTGCTATCAGCCCCGGCGTGGCAATTGCC
GAGCCACTGGTGCAGGCTGCATTGCAACAGGGCGTATCAGTAATAGGAGATATCGAGCTGTTCGCCATTGCACTTGATCA
GCACGCGCCACCGGGTACGAAAATTCTGGCAATTACCGGATCTAATGGGAAAACCACTGTTGCCACCATGGTAGGTGAAA
TGGCAAGGAATACCGGATGGGATGTTGAAGTAGCGGGTAACATCGGCCTGGCGGCGCTGGATGCGCTGATGCAGCGAATA
GATACAGGAAAATGGCCGCATTTATGGGTACTTGAGCTGTCAAGTTTTCAGCTAGAAACCACCAGCAGTTTACGTCCCAA
TGCTGCCGTCGTATTAAACCTCAGCGAAGATCATCTGGACCGCTACCGCATTATCGAGGAATACGCAGCCGCAAAAGCAA
GGATATTTCCCGATCCACATAACAGTTGTGTGCAGGTACTCAACCGGGAAGATGCCCGGGTATACGCCATGGCTCACGAA
AACAGCAAACAATTAACTTTTGGTTTGTCCGCACCGGCATTCGACGATGAATTCGGTGTGTTACCCAGTGGATCAGATTT
GTGGTTGGCACAGGGCACCACTCGCTTGATGAAAGTCAGCGAACTTGCTGTCGCGGGATTGCATAACGCGGCCAACGCAC
TGGCGGCACTGGCATTATGTCGGGCCATTGATCTACCTTTTGAACCGTTGTTGCATGCTTTGCACATCTTCAAGGGATTG
CCGCATCGCATGCAGAAGATTGCCGAGTTCAATGGCGTGACTTTTTATGATGATTCCAAAAGCACCAACGTGGGCTCCGC
CGTTGCCGCACTGAATGGTTTCCGAAAAAACGTGATTCTGATTGCAGGCGGAGATGGCAAAGGGCAGGATTTCTCACCTC
TGGAACAGCCTGTCAGCAAACATACACGCGGTGTTGTACTGCTGGGAAGAGATGCCGAGAAAATTTCACAGGCAATTCAG
GGCTGCAATGTACCGGTACATCGCGTGGCAACTATGGATGAGGCTGTCCGGGTAAGTTTTTTGCTGGCAGAGCGTGGCGA
TAGCGTTCTACTCTCCCCGGCCTGTGCCAGTCTTGATATGTTCAACAACTACATCCATCGCGCTGAGGTTTTTACGACCG
CTGTCCAGGGAATCGAACACAAATTTATACTCACGGCACAGACATGTCACTAA

Protein sequence :
MNYADKKILVLGMGKTGISMVKWLSRAGARVSVADTRTTPPNLELLSQIVPLETIFCGPFKAELFKDIDAIAISPGVAIA
EPLVQAALQQGVSVIGDIELFAIALDQHAPPGTKILAITGSNGKTTVATMVGEMARNTGWDVEVAGNIGLAALDALMQRI
DTGKWPHLWVLELSSFQLETTSSLRPNAAVVLNLSEDHLDRYRIIEEYAAAKARIFPDPHNSCVQVLNREDARVYAMAHE
NSKQLTFGLSAPAFDDEFGVLPSGSDLWLAQGTTRLMKVSELAVAGLHNAANALAALALCRAIDLPFEPLLHALHIFKGL
PHRMQKIAEFNGVTFYDDSKSTNVGSAVAALNGFRKNVILIAGGDGKGQDFSPLEQPVSKHTRGVVLLGRDAEKISQAIQ
GCNVPVHRVATMDEAVRVSFLLAERGDSVLLSPACASLDMFNNYIHRAEVFTTAVQGIEHKFILTAQTCH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 6e-68 45
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 6e-68 45