Gene Information

Name : Neut_0226 (Neut_0226)
Accession : YP_746475.1
Strain : Nitrosomonas eutropha C91
Genome accession: NC_008344
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 239762 - 241036 bp
Length : 1275 bp
Strand : +
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: neu:NE2276 UDP-glucose/GDP-mannose dehydrogenase family

DNA sequence :
ATGCAACTCCAGGATATCAAACTTGCCATTATCGGGCTTGGATATGTCGGCCTTCCACTGGCTGCTGAGTTTGGCCGCAA
GCGTCCTGTGACCGGGTTCGATATTAACCAGCAGCGTATTGATGAGCTTAAAAATGGCAATGACTTTACGCTGGAAGTCA
CGCAGGAAGAACTTGCAGCGGCAAAGCATTTGACTTTTACCACCAATATAGACGATTTACGCACCTGTAATTGCTACATT
ATTACCGTTCCCACACCAATTGATGATCACAAGCGCCCTGATCTTATGCCACTTATCAAAGCCAGCGAGACTGTCGGTAA
GGTATTGAGAAAAGGAGATATTGTTATTTATGAATCTACTGTCTACCCTGGTTGTACCGAAGAAGATTGTGTGCCTGTGC
TGGAGCGTGTTTCTGGCCTGAAATTTAACCGGGATTTCTACTGTGGCTACAGTCCAGAGCGCATCAACCCAGGTGACAAG
GAACATCGTGTCACGACTATCAAAAAGGTTACCTCGGGCTCCACTCCGGAAATCGCTGATCTGGTAGATAGCTTATACAA
CGAAATTATTACTGTAGGCACACACAAAGCGGAAAGTATCAAGGTGGCTGAAGCTGCCAAGGTGATCGAAAACACCCAGC
GTGATCTGAATATTGCTCTTATCAACGAGCTGGCGTTGATTTTCAACAAAATGAATATTGATACTGAAGCCGTACTCAAA
GCAGCGGGCAGTAAGTGGAATTTTCTGCCGTTTCGTCCCGGTCTGGTGGGTGGACATTGTATTGGGGTGGATCCGTATTA
CCTGACACATAAAGCGCAGGCAATTGGCTATCATCCGGAAATTATTCTTGCTGGACGGCGACTAAATGACAGCATGGGAG
CCTATGTTGTTGCTCAGCTGGTTAAAGCCATGACCAAAAAACGTCTTCAGGTAGATGGCGCCAAGGTATTGGTCATGGGA
CTTACCTTCAAGGAAAACTGTCCGGATCTGCGTAATACCCGAGTGGTGGATATCGTGACCGAACTCAAGGATTACAACTG
CGTAGTGGATGTATACGATCCATGGTTGTCTTCTGAAGAGGCACAACACGAATACAGTATCAAGCTGATTGAAGCACCCG
AATCCGGTAATTATGATGCTATTATCCTGGCTGTGGCACATCGGCAGTTCAAGGATATGGGGGCTTCCTCTATCCGTGCA
CTGGGGAAACCCAATGCTGTTCTATATGATTTGAAGTATGTGCTTAATCCACAGGAATCAGATCTGAGGCTGTAA

Protein sequence :
MQLQDIKLAIIGLGYVGLPLAAEFGRKRPVTGFDINQQRIDELKNGNDFTLEVTQEELAAAKHLTFTTNIDDLRTCNCYI
ITVPTPIDDHKRPDLMPLIKASETVGKVLRKGDIVIYESTVYPGCTEEDCVPVLERVSGLKFNRDFYCGYSPERINPGDK
EHRVTTIKKVTSGSTPEIADLVDSLYNEIITVGTHKAESIKVAEAAKVIENTQRDLNIALINELALIFNKMNIDTEAVLK
AAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAIGYHPEIILAGRRLNDSMGAYVVAQLVKAMTKKRLQVDGAKVLVMG
LTFKENCPDLRNTRVVDIVTELKDYNCVVDVYDPWLSSEEAQHEYSIKLIEAPESGNYDAIILAVAHRQFKDMGASSIRA
LGKPNAVLYDLKYVLNPQESDLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-144 69
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-144 69
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-108 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Neut_0226 YP_746475.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 6e-145 69