Gene Information

Name : Neut_0116 (Neut_0116)
Accession : YP_746369.1
Strain : Nitrosomonas eutropha C91
Genome accession: NC_008344
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 112738 - 114753 bp
Length : 2016 bp
Strand : -
Note : KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA

DNA sequence :
ATGAGGTTATTTCTGTGCGAGAAGCCTTCCCAGGGCAAAGACATCGGCAAAGTGCTTGGCGCCACGCAGCGCGACAACGG
TTGCCTGAAAGGCCCGGGCGTCATCGTGACCTGGTGCATTGGCCATCTGGTCGAGGCGGCGCCGCCAGAAGCTTATGACG
CAAATCTCAAACACTGGTCCATCGAACAGTTGCCCATTATTCCCGAGCGCTGGCGTATCGAAGTCAAACCCAAGACCGCC
GCGCAATTCAAAGTCGTCAAGCAGTTGCTGGCACAAGCTACCGAGTTGGTGATCGCCACCGACGCGGATCGTGAAGGCGA
AATGATCGCCCGTGAAATTGTTGAGCTGTGTGGCTACCGAGGGCCTATTCAACGCCTGTGGCTATCGGCCCTGAATGATG
CATCGATCCGCAAGGCATTGGCTGCCCTGAAACCGTCATCTGAGACGCTGCCCATGTACCATTCGGCCTTGGCGCGCTCC
CGCGCCGACTGGCTGGTGGGCATGAACCTGAGTCGGCTTTTCACTCTATTGGGTCGGCAGGCTGGCTACGATGGCGTGTT
GTCGGTAGGTCGGGTGCAAACGCCCACGTTAAAGCTCGTGGTGGATCGCGACCGTGAAATCAATCAGTTTGTCTCCATCC
CATTCTGGGCTATCGACGTAGCGCTCTCAGCAACAGGACAATCTTTCATCGCGCAGTGGCTGGCCCCCGAAGCCTGCACC
GACGAGGCGGGAAGGTGCCTGCAGGAGTCCGTGGCACAACAGGCGGCGCAACAATTGCGTGCAAACGGCACCGCTCAGGT
CGCGTCCGTCGAAACCGAACGGGTGCGCGAGGGCCCGCCATTGCCCTTCGATCTTGGGACGTTGCAGGAAGTCTGTTCCA
AGCAGCTTGGCCTGGATGTGCAGGAAACGCTGGACATTGCCCAGGCGTTGTACGAAACGCATAAGGCCACCACCTATCCA
CGCTCGGATTCGGGCTACCTGCCCGAGAGTATGCAGGCCGATGTGCCAGCCGTGCTCGACAGCCTGCTCAGAACCGATCC
CGCCTTGCGGCCCGTGATGGAGCAGCTTGATCGCAGACAGCGTTCACGGGCCTGGAACGACAGCAAGGTCACCGCTCACC
ATGGCATCATCCCCACGCTGGAACCCGCGAACCTCTCGGCCATGAGCGAGAAGGAGCTGGCCGTTTATCGACTGATCCGT
GCCCATTACCTAGCACAGTTTCTACCGCATCATGAATTTGACCGCACCATTGCGCGGCTTTCGTGCGCGGGTCAACATCT
TCAGGCCGTAGGCAAACAGATTGTCATCCCAGGATGGCGGCTGGTGCTGGTCGAGCAGCAAGCGGAGGATGCCGACGATG
AGGCCGCCCCGCGCAGTCAAGTGTTGCCCGCACTGAACCAAGGCCTGTCCTGCCAGATGAACACCGTTGATCTTAAGGCG
CTCAAGACGCTGCCTCCCCGGCCCTACACCCAAGGAGAGCTGGTCAAGGCCATGAAAAGTGTCGCCAAGCTGGTGTCCGA
CCCACGCCTGAAGCAGAAGCTCAAGGACACGGTTGGCATCGGCACCGAGGCCACTCGCGCCAATATCATCAACGGGCTGC
TGACACGTGGCTATCTGATCAAGAAGGGCCGGGCGATCCGTGCGTCGGAAGCGGCTGGCACGCTCATTGATACGGTTCCC
GCGGCCATTGCTGACCCCGGCACGACAGCAGTCTGGGAGCAGGCCCTGGACATGATCGAGGCGGGCGAGCTTACCCATGA
CGTCTTCACCGGCAAGCAGTCGGCCTGGATTTCACAGATCATCGCCCAGTACCAGGGCACAGCCATGACGATCAAGGTGC
CCCAAGGTCCAGCTTGCCCGCAGTGCGGCTCGGCCACACGCCAACGCACTGGCAAAAATGGTCCGTTCTGGTCATGCTCG
CGTTATCCCGAGTGCAAAGGCACCGTGCCGGTTGACTCCGCAACGCCCAAGCGCAGCGCGCCGCGCAAGCGCCGCAGCGC
ATCCAAGACATCCTGA

Protein sequence :
MRLFLCEKPSQGKDIGKVLGATQRDNGCLKGPGVIVTWCIGHLVEAAPPEAYDANLKHWSIEQLPIIPERWRIEVKPKTA
AQFKVVKQLLAQATELVIATDADREGEMIAREIVELCGYRGPIQRLWLSALNDASIRKALAALKPSSETLPMYHSALARS
RADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLKLVVDRDREINQFVSIPFWAIDVALSATGQSFIAQWLAPEACT
DEAGRCLQESVAQQAAQQLRANGTAQVASVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYP
RSDSGYLPESMQADVPAVLDSLLRTDPALRPVMEQLDRRQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKELAVYRLIR
AHYLAQFLPHHEFDRTIARLSCAGQHLQAVGKQIVIPGWRLVLVEQQAEDADDEAAPRSQVLPALNQGLSCQMNTVDLKA
LKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDTVGIGTEATRANIINGLLTRGYLIKKGRAIRASEAAGTLIDTVP
AAIADPGTTAVWEQALDMIEAGELTHDVFTGKQSAWISQIIAQYQGTAMTIKVPQGPACPQCGSATRQRTGKNGPFWSCS
RYPECKGTVPVDSATPKRSAPRKRRSASKTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 82
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 78
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 66
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-167 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-167 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-167 51
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 7e-167 50
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 5e-165 50
topB AAW83109.1 TopB Not tested GGI Protein 4e-125 42