Gene Information

Name : thyA (Neut_1021)
Accession : YP_747243.1
Strain : Nitrosomonas eutropha C91
Genome accession: NC_008344
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1054635 - 1055429 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCATCCATACCTTGATCTAATGCGACATGTGTTGCAATACGGTCATAAAAAAACTGATCGCACCGGTACCGGGACACT
TTCCATCTTCGGTTATCAGATGCGTTTTGATCTGCAACAGGGGTTCCCGTTGGTAACAACCAAGCAATGCCATGTCAAAT
CGATCATCCACGAATTGCTGTGGTTTCTGCGCGGCGATACCAATATTGACTATCTGAAGAAAAATGGTATTTCCATCTGG
AATGAATGGGCAGATAAAAGCGGGGAGCTGGGACCGGTTTATGGCCACCAGTGGCGTTCCTGGACTGTTTCCGGTGACAA
ATCCATCGATCAGATTGCGCAAGTAATCCAGCAAATCAAAGCAACACCGGATTCACGCCGGATGATTATTTCTGCTTGGA
ACGTGGGAGATCTCGACAAAATGGCACTCGCTCCCTGCCATGTCCTGTTTCAGTTTTATGTGGTGGATGGCAAGCTCTCC
TGCCAACTTTATCAGCGCAGCGCGGATATTTTCCTGGGTGTTCCATTCAACATTGCTTCCTATTCGTTGCTGACACTAAT
GATCGCGCAGTGCTGCAATCTCAAGCCTGGTGAATTCATCCATACATTTGGAGATGCACACCTGTATCTGAATCACCTTG
AACAAGCTCGCCTGCAACTGACTCGTGAACCAAAATCCCTTCCCATAATGGAGCTGAATCCGGCAATCAGAAATATTCTT
GATTTCAGGTACGAGGATTTCACCTTACATAATTATGATCCACATCCGCCCATCAAGGCGCCTGTTGCCGTATGA

Protein sequence :
MHPYLDLMRHVLQYGHKKTDRTGTGTLSIFGYQMRFDLQQGFPLVTTKQCHVKSIIHELLWFLRGDTNIDYLKKNGISIW
NEWADKSGELGPVYGHQWRSWTVSGDKSIDQIAQVIQQIKATPDSRRMIISAWNVGDLDKMALAPCHVLFQFYVVDGKLS
CQLYQRSADIFLGVPFNIASYSLLTLMIAQCCNLKPGEFIHTFGDAHLYLNHLEQARLQLTREPKSLPIMELNPAIRNIL
DFRYEDFTLHNYDPHPPIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-77 62