Gene Information

Name : GbCGDNIH1_2375 (GbCGDNIH1_2375)
Accession : YP_746196.1
Strain : Granulibacter bethesdensis CGDNIH1
Genome accession: NC_008343
Putative virulence/resistance : Virulence
Product : L-lysine 6-monooxygenase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3486
EC number : 1.14.13.59
Position : 2639993 - 2641318 bp
Length : 1326 bp
Strand : -
Note : -

DNA sequence :
ATGACGGATCGTTTTCAGTTTTCTGCCTTTCCGTTACAGGATCTTGCGGCGATCGGGATCGGGCCGTTCAATCTGAGTGT
CGCGGCCCTGCTGGATGCTGTGCCGGAGGTGCAGGCGCAGTTTTTTGATCGTAGCCCGCGCTTTGCCTGGCATCCCGGCA
TGATGCTGCCTGATGTCACTTTGCAGACATCATGGTTGAAGGATCTGGTCAGTGCCGTACAGCCGACCAGCCCGTTCAGC
TTTACCTCCTATCTGGTGGCACGGCGCCGGTTTTACGAATTCATCACAGCCGGATTTGAAGGAATCTATCGCCGGGAATT
CGATGATTATCTTGGCTGGGTTGCAGCACAGCTTCCATCGCTGCATTTCGGAACCCCCGTTGAGTCGGTTGATTTCGATG
GCCGTCACTTTGTGCTGACGCACCGCCATGGAGAAGTCAGAGCGCGCAATGTGTTGATCGGAACCGGGCATCATCCCTAT
CTGCCGCGCTGGGCGGCTGGTCTGGAAGATATGTGCCTGCATACATCCCGTTTTGCCGAGAAAGACCGTGATTACACGGG
TCGCCATGTCATTGTGGTCGGTGGGGGGCAGAGCGGTGCGGAAATCGTGCTTGATCTGCTGCGCCGGGGGCCAGACCGTG
TGGGGGGAATCACCTGGATCACGCGCCGGATGAATTTCTCGTCACTGGATGAAGTGGCTTTCAGCAACGAGTATTTTACG
CCGGCCTATGTCGCGCGCTTCCATGGGCTGCCGCCTGATCTCCGTGCCCGGCATGTGGCCGCGCAGAAACTGGCCAGTGA
TGGGGCTTCCCCGACGACACTGAACGAGATCTACCGCGCGCTATACCAGATCCGGCATCTCGATGGCCGACGCGATTTCG
TGCGGCTGATGCCATATCGGGAGGCAGAGGCTGCAAGGCGTCACGGAGAAGGGATTACCCTGCATCTGCGTCATCACCTG
GATGGTCAGATGGATACGGTCACCGGGGATACGGTCATCTGTGCAACCGGATACAAGGCAGCTGTGCCAGCCTGTTTTGG
ATCGCTCCAGAAGCGCCTCAAACTGGATGAGGAAGGACGTTACACATTGCGGCCCGATTTTTCTGCTGTCTGGGATGGTC
CTGCTTCTGCCCGCATCTTTGTCCAGAATGCAGGACGCCACAGCCATGGGATTGCCGAACCTCAACTCAGTCTGATGGCA
TGGCGGGCTGCGACAATCATCAACAGCCTGCTCGGCCGGCCGCATTTCGATCTGGAGGAACCGGAACCATTGGTGGATTG
GGGAGTGGAGAGGGAGGATGAGACCTCCCGTCTCGCGGCTGAATAA

Protein sequence :
MTDRFQFSAFPLQDLAAIGIGPFNLSVAALLDAVPEVQAQFFDRSPRFAWHPGMMLPDVTLQTSWLKDLVSAVQPTSPFS
FTSYLVARRRFYEFITAGFEGIYRREFDDYLGWVAAQLPSLHFGTPVESVDFDGRHFVLTHRHGEVRARNVLIGTGHHPY
LPRWAAGLEDMCLHTSRFAEKDRDYTGRHVIVVGGGQSGAEIVLDLLRRGPDRVGGITWITRRMNFSSLDEVAFSNEYFT
PAYVARFHGLPPDLRARHVAAQKLASDGASPTTLNEIYRALYQIRHLDGRRDFVRLMPYREAEAARRHGEGITLHLRHHL
DGQMDTVTGDTVICATGYKAAVPACFGSLQKRLKLDEEGRYTLRPDFSAVWDGPASARIFVQNAGRHSHGIAEPQLSLMA
WRAATIINSLLGRPHFDLEEPEPLVDWGVEREDETSRLAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucD AAK71634.1 IucD Virulence SHI-3 Protein 3e-89 45
iucD NP_839220.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 2e-89 44
iucD NP_709457.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 2e-89 44
iucD YP_002414043.1 L-lysine 6-monooxygenase Virulence Not named Protein 6e-90 44
iucD AAD44749.1 IucD Virulence SHI-2 Protein 1e-89 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GbCGDNIH1_2375 YP_746196.1 L-lysine 6-monooxygenase VFG1084 Protein 1e-89 45
GbCGDNIH1_2375 YP_746196.1 L-lysine 6-monooxygenase VFG0618 Protein 8e-90 44
GbCGDNIH1_2375 YP_746196.1 L-lysine 6-monooxygenase VFG0937 Protein 3e-90 44