Gene Information

Name : GbCGDNIH1_1993 (GbCGDNIH1_1993)
Accession : YP_745814.1
Strain : Granulibacter bethesdensis CGDNIH1
Genome accession: NC_008343
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2237681 - 2238445 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGACCCCTCTCATCGTCATTCCCAGCCGCATGGGATCGAGCCGCCTGCCCGGCAAACCTCTCGCCGATCTCAACGGGCG
CCCGATGATCCTGCATGTGCTGGACCGGGCGATGGAGGCCGGGATCGGGCCGGTGGCTGTCGCCTGCGCAGAAGAAGAAA
TCGCCGCCGCCGTGCGCGCCGCAGGGGGAACCGCCATCCTGACCGATCCGGACCTGCCCGCCGGGACCGACCGTGTGCAT
GCGGCACTTGGCGTGCTCGATCCGGAGATGCGATATAATGCGGTGGTCAATCTTCAGGGCGATCTGCCCACCATCCCGCC
GGACATGATCAGCACGGTGCTGAAGCCTCTGCGCAGCCCGACTTTCGACATCGCTACGCTGGTGGCGGAAATCACCACTG
AGGAAGAGCGGACCTCCCCCGCCGTGGTCAAGGCCGTCTGCGCTTTTCCCGATCCGTCCGGCACCGTTGCTCCGGCACTG
TATTTCTCCCGTGCGGCGGTCCCATCAGGACCGGGATCGCTCTGGCATCATATCGGCATTTATGCCTATCGGCGTACCGC
GCTGGACCGGTTTGTCTCCCTGCCTGAAAGCCCGCTGGAAAAACGCGAGAAGCTGGAACAGCTGCGTGCGTTGGAAGCAG
GCATGCGGATTGGCTGCGCCCGCGTCGAGCACGCGCCCTTCGGCGTCGATACGCCGGACGACCTGGAACGCGCCCGCGCG
GTGCTCCGCACCTGGTCATCCTCCGTCACGGAGCCTTCGGCATGA

Protein sequence :
MTPLIVIPSRMGSSRLPGKPLADLNGRPMILHVLDRAMEAGIGPVAVACAEEEIAAAVRAAGGTAILTDPDLPAGTDRVH
AALGVLDPEMRYNAVVNLQGDLPTIPPDMISTVLKPLRSPTFDIATLVAEITTEEERTSPAVVKAVCAFPDPSGTVAPAL
YFSRAAVPSGPGSLWHHIGIYAYRRTALDRFVSLPESPLEKREKLEQLRALEAGMRIGCARVEHAPFGVDTPDDLERARA
VLRTWSSSVTEPSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-30 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-30 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 9e-31 44