Gene Information

Name : guaA (GbCGDNIH1_1150)
Accession : YP_744971.1
Strain : Granulibacter bethesdensis CGDNIH1
Genome accession: NC_008343
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1287350 - 1288918 bp
Length : 1569 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCGACATTCTCGAACAGATCGTTGATCGGGTTCTGATTCTGGATTTCGGCAGTCAGGTCACTCAGCTTATTGCCCG
CAGAGTCCGCGAATCAGGGGTTTATTGCGAAATCTGGCCATTTACCGCGGATGCCGAGCGTATCCGCACCTATGCACCGC
AAGGCATTATCCTTTCAGGGGGCCCATCCAGCGTGGCGCTGGCAGGATCTCCGCGCGCACCGGATGTCGTGTTCTCGATG
GATATCCCTGTGCTGGGTATCTGCTACGGCCAGCAGACGATGTGCGTGCAGCTTGGAGGCTCGGTCGAGGGCAATGACCA
TCAGGAATTCGGCCGCGCCCATGTTGATGTCGTGGAGAATTGTCGGATCACCGACGGTCTGTGGGAAAAAGGCGCGCGTG
AGCAGGTCTGGATGAGTCATGGCGACCGGGTCACTGCTTTACCCCCCGGTTTCCGTGCGGTAGCCGTCAGCGAGGGCGCG
CCTTTCGCGATGATTGCCGATGATGATCGCCGTTTTTACGGTGTGCAGTTTCATCCGGAGGTGATCCACACCCCGCATGG
CACGCAGTTGCTGCGTAACTTCACACATGCGGTTTGCGGCTGCTCCGGCGGCTGGAGCATGGCGGCATTCCGCCCTGCTG
AAATCAAGCGTATCCGGGAGATTGTCGGTGAAGGGCGCGTTATTTGCGGCCTGTCCGGCGGCGTTGATTCAACCGTGGCG
GCGGTGCTGATCCATGAGGCGATTGGCGACCAGCTCACCTGTATTTTCGTGGATCATGGCCTGCTGCGCCAGAGTGAGGC
GGAACAGGTGCTCGCTATGTTCCGTGACCGTTTTAACATCAAACTGGTGCATCGTGACGCTTCCGATCTGTTCCTCGGGG
CGCTGGAAGGGGTCAGCGACCCTGAGGTAAAGCGCAAGACAATCGGCAAGCTGTTCATTGATGTATTCGAGGAAGAAGCC
GCCAAGATCGGCGGCGCTGATTTCCTGGCGCAAGGTACACTTTATCCGGATGTGATCGAGAGCATCAGCTTTACCGGTGG
TCCTTCGGTCACGATCAAATCCCACCACAATGTCGGTGGCCTGCCAGAGCGGATGCGAATGAAACTGGTCGAACCGCTTC
GCGAATTGTTCAAGGACGAGGTGCGCGCACTGGGTCTTGAACTGGGCCTGCCGAAAGAAATGGTCGGCCGCCACCCCTTT
CCCGGCCCGGGCCTTGCCATCCGTATTCCCGGAGCGATCAGCAAGGACCGTCTTGAAATCCTGCGTCGTGCTGATGCCAT
TTATCTGGAGGAAATCCGCAATGCCGGTCTCTATGACGAGATCTGGCAGGCTTTCGCGGTTCTGCTGCCAGTCCGCACTG
TAGGCGTGATGGGCGATGGCCGCACCTATGACTTCGCCTGCGCCCTGCGTGCCGTCACCAGCACGGATGGCATGACGGCG
GATGTCTATCCGTTTGATATCAAGTTCATTGCGAGAGTGGCTAACCGCATCGTCAATGAGGTGCGGGGGATCAATCGTGT
GGCCTACGATATTACATCGAAGCCACCGGGAACAATTGAGTGGGAATGA

Protein sequence :
MSDILEQIVDRVLILDFGSQVTQLIARRVRESGVYCEIWPFTADAERIRTYAPQGIILSGGPSSVALAGSPRAPDVVFSM
DIPVLGICYGQQTMCVQLGGSVEGNDHQEFGRAHVDVVENCRITDGLWEKGAREQVWMSHGDRVTALPPGFRAVAVSEGA
PFAMIADDDRRFYGVQFHPEVIHTPHGTQLLRNFTHAVCGCSGGWSMAAFRPAEIKRIREIVGEGRVICGLSGGVDSTVA
AVLIHEAIGDQLTCIFVDHGLLRQSEAEQVLAMFRDRFNIKLVHRDASDLFLGALEGVSDPEVKRKTIGKLFIDVFEEEA
AKIGGADFLAQGTLYPDVIESISFTGGPSVTIKSHHNVGGLPERMRMKLVEPLRELFKDEVRALGLELGLPKEMVGRHPF
PGPGLAIRIPGAISKDRLEILRRADAIYLEEIRNAGLYDEIWQAFAVLLPVRTVGVMGDGRTYDFACALRAVTSTDGMTA
DVYPFDIKFIARVANRIVNEVRGINRVAYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-131 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-131 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-131 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-116 51