Gene Information

Name : murD (Mlg_2195)
Accession : YP_743027.1
Strain : Alkalilimnicola ehrlichii MLHE-1
Genome accession: NC_008340
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 2500728 - 2502077 bp
Length : 1350 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGCAGGCAGTGAAACGGCAAGCAGGATACCGCGCGGTGGTTGGCCTCGGCCGCACCGGGCTGGCCTGTGTCCGTTTCCT
GGCCGCCCGCGGGCTCGATGTGTGCGTCACCGACAGCCGCGACGAGCCGCCGGAGCAGGCCACCCTGCAACGGGAATGGC
CGCAGGTGCCGGTGCGCGCGGGCGGCTTCGACGCCGCCCTGCTGGCGGGCGCCGGGGAGATCATCGTCAGTCCCGGGGTC
AGTCTCCGGGAGCCGGCGCTGGAGACCGCCCGCCGGGCCGGTGTGCCGTTGATCGGCGAGATCGAGCTGTTTGCCCGTCA
CGCCGATGCGCCGGTGGCGGCGATCACCGGCTCCAATGGCAAGAGCACGGTCACCACCCTGGTGGGGCGAATGGCCGAGG
CGGCGGGCCGGCGGGTGGCGGTGGGCGGCAATCTGGGCACCCCGGCACTGGCACTGCTGGATGGGGAGACCCGGCCCGAT
GCCTACATTCTGGAGCTCTCCTCCTTTCAGCTCGAGACCACCCACAGCCTGGCCCCCCGGGTGGCGGCGGTGCTCAACAT
CAGCGCCGACCACATGGACCGCCACGGCAGTGTCAGCGCCTACGCCGGGATCAAGGCGCGTATCTTCCACGGCGCCGGCG
TCCAGGTGCTCAACCTGGACGATCCGGTGGTGGCCGCCATGGCGCAACCCGGCCGCACGGTCCTGGGCTTCAGCCTGGCG
TCCAACCCGCGCCGGGGGGCCGGCGTGGCCGACCACCGGGGCGCCCCGTGGCTGCACCTGAATGGTGAGCCGGTCCTGCC
GGCGGCGGACCTGCGGCTGCCCGGGCTGCACAACCGCGCCAACGCCCTGGCCGCCCTCTGCCTGGGGCAGGGACTGGGCC
TGCCGGTGGCGGCGATGGCCGAGGCGCTGCGCCGTTTCACCGGCCTGCCCCACCGCACCGAATGGGTGGCCGAGCACGCC
GGTGTGCGCTGGTACAACGACTCCAAGGGGACCAATGTGGGGGCGGCCGTGGCCGCCATCCGTGGCCTGGCGGGCCCGGT
GGTGCTGATCGCCGGCGGCGACGGCAAGGGGGCCGACTTCTTGCCGCTGGCCGACGCGCTTCGCGAGAAGGGCCGGGCGG
CGGTGCTGATCGGCCGGGACGCCCCGCGCCTGGCGCAGGTGCTCTCCGGGGTGGTGCCGGTGGAGCGGGCCGCGGATATG
AGGGACGCCGTGCGCCGGGCGGCCAACCTGGCCCGGTCCGGCGACGCGGTGCTGCTGTCGCCCGCCTGTGCCAGCTTCGA
TATGTTCCGGGGCTTCGAGCACCGGGGTGAGGCCTTCCGCGACGCGGTACGGGAGGTGGCCCATGGCTGA

Protein sequence :
MQAVKRQAGYRAVVGLGRTGLACVRFLAARGLDVCVTDSRDEPPEQATLQREWPQVPVRAGGFDAALLAGAGEIIVSPGV
SLREPALETARRAGVPLIGEIELFARHADAPVAAITGSNGKSTVTTLVGRMAEAAGRRVAVGGNLGTPALALLDGETRPD
AYILELSSFQLETTHSLAPRVAAVLNISADHMDRHGSVSAYAGIKARIFHGAGVQVLNLDDPVVAAMAQPGRTVLGFSLA
SNPRRGAGVADHRGAPWLHLNGEPVLPAADLRLPGLHNRANALAALCLGQGLGLPVAAMAEALRRFTGLPHRTEWVAEHA
GVRWYNDSKGTNVGAAVAAIRGLAGPVVLIAGGDGKGADFLPLADALREKGRAAVLIGRDAPRLAQVLSGVVPVERAADM
RDAVRRAANLARSGDAVLLSPACASFDMFRGFEHRGEAFRDAVREVAHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 4e-64 46
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 4e-64 46