Gene Information

Name : murD (Shewmr7_0384)
Accession : YP_736444.1
Strain : Shewanella sp. MR-7
Genome accession: NC_008322
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 427044 - 428363 bp
Length : 1320 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGCAAAGTCAGTACTCACACATAGTGTTAGGTTTGGGTGCCACCGGGCTCTCGGTAGTGCGCTATTTGTGTGGAAAAGG
GATCACACCCTTGGTGATGGATAGCCGTCGCCAACCTCCAGGTGCGGACACCCTTGCCAGCGCATTCCCTGAGGTGCAGC
TGATTGCGGGCGGATTCGATTGCCGTTACTTAGTGCAAGCAAAGCAAATCATTATCAGCCCTGGCATTGCGATTGATACG
CCTGAGGTGCGCGCTGCACTGGATATGGGGATTGAAGTCATTGGCGATGTGGAGCTATTTGCCCGTGAGATTGCCGACCG
TAAACCTTGTGTGCTTGGGATTACTGGCTCAAACGGCAAGTCGACCGTTACCACCTTAGTGGGTGAAATGCTGCGTGAAG
CAGGCATGGCGGTGGCAGTGGGTGGCAATATTGGCATTCCTGCGCTCGATCTGCTGACGGAAAATGCCGATATTTTTGTG
CTTGAGCTGTCGAGCTTCCAGCTCGAAACCACCCACAGCTTAAACTGCGTGGCGTCGACCTGCTTGAACGTGACCGAAGA
TCATATGGACAGATACAGCGATATGGATGCCTATCGCAAGGCCAAGCTGCGCCTGTACCATCAAAGCCGCTCCATCATCT
TTAACCGTGATGATGCGCTGACTATCCCGACAGAGCCGATGAACCAAAACAGCTTTGGTTTAGCGCCGCCAGAGGGCGAC
GAGTGGGGCATTTGTGATAGCAAGATTTACCACGGTCACAGTGAAATTATGCCGATCACCGAAGTATCGCTGATTGGTAG
TCATAACCATGCCAACTTACTCGCTGCCATGGCGCTGGTGTATGCCGTGGGCGTAGATAAGCAAGTCATGGCTAAAGTGG
CTCGTACCTTTACTGGCCTTTCTCATCGCTGTGAAGTGGTTGGTGTAAAAGCGGGCGTGACCTATGTGAACGATTCGAAG
GCGACCAATGTTGGCGCCACCGTCGCGGCGCTCGATGGGTTGAGCGATCACTTAGGTGACATTATTTTAATTGCCGGTGG
TGATGGTAAGGGCGCGGATTTCAGTCCGTTGGTCGAGCCGTTAACGAAAGTGACACACCTCATCACCTTAGGTCGCGATG
GCAATAAGGTAGCCGCATTGAAGGAAGGGGCCATTAAGGTGGACTCTATGGCTGCAGCAGTGGCTAAGGCCGCCGAGTTA
GCCACCTCGGGCGATATCGTACTCCTATCGCCAGCCTGTGCGAGCCTAGATATGTACAGCAACTTTATGGCTCGTGGGGA
TGATTTTAGAAGCCAAGTGGAGCAACTCGATGGCGAGTGA

Protein sequence :
MQSQYSHIVLGLGATGLSVVRYLCGKGITPLVMDSRRQPPGADTLASAFPEVQLIAGGFDCRYLVQAKQIIISPGIAIDT
PEVRAALDMGIEVIGDVELFAREIADRKPCVLGITGSNGKSTVTTLVGEMLREAGMAVAVGGNIGIPALDLLTENADIFV
LELSSFQLETTHSLNCVASTCLNVTEDHMDRYSDMDAYRKAKLRLYHQSRSIIFNRDDALTIPTEPMNQNSFGLAPPEGD
EWGICDSKIYHGHSEIMPITEVSLIGSHNHANLLAAMALVYAVGVDKQVMAKVARTFTGLSHRCEVVGVKAGVTYVNDSK
ATNVGATVAALDGLSDHLGDIILIAGGDGKGADFSPLVEPLTKVTHLITLGRDGNKVAALKEGAIKVDSMAAAVAKAAEL
ATSGDIVLLSPACASLDMYSNFMARGDDFRSQVEQLDGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-58 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-58 42