Gene Information

Name : Shewmr7_3328 (Shewmr7_3328)
Accession : YP_739367.1
Strain : Shewanella sp. MR-7
Genome accession: NC_008322
Putative virulence/resistance : Resistance
Product : Beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2602
EC number : 3.5.2.6
Position : 3943670 - 3944467 bp
Length : 798 bp
Strand : -
Note : PFAM: penicillin-binding protein, transpeptidase; KEGG: son:SO0837 beta-lactamase, putative

DNA sequence :
ATGCGTGCGTTAGCCTTATCGGCTGTGTTGATGGTGACAACGATGATTGGCATGCCTGCGGTGGCAAAGGAGTGGCAAGA
GAACAAGAGTTGGAATGCTCACTTTAGCGAACATAAAACCCAAGGCGTGGTTGTGCTCTGGAACGAGAATAAACAGCAGG
GTTTTACTAACGATCTTAAACGGGCAAACCAAGCATTTTTACCGGCATCGACTTTTAAGATCCCAAACAGTTTAATTGCC
TTGGACTTAGGTGTGGTTAAGGATGAGCATCAGGTCTTTAAATGGGATGGACAGACGCGAGATATCGCCGCGTGGAATCG
TGACCATGACTTAATTACCGCGATGAAGTACTCGGTTGTGCCTGTTTATCAAGAATTTGCCCGCCAAATTGGCGAGGCGC
GTATGAGTAAAATGCTGCATGCCTTCGATTATGGCAATGAGGATATCTCGGGCAATTTGGACAGTTTTTGGCTCGATGGT
GGTATTCGCATTTCGGCTACCCAGCAAATCGCTTTTTTACGCAAGCTCTACCACAACAAGCTGCACGTCTCTGAGCGTAG
TCAGCGCATCGTCAAACAAGCCATGCTGACCGAAGCAAATGCCGACTATATCATTCGGGCGAAAACGGGTTATTCGGTCA
GAATTGAGCCGAAAATCGGTTGGTGGGTTGGCTGGGTCGAACTCGATGACAATGTGTGGTTCTTCGCGACCAATATGGAT
ATGCCTTCCGCTGAGGGCTTAGGGTTACGTCAAAGCATTACGAAAGCAGTGCTAAAACAGGAAAAAATTATTCCTTAG

Protein sequence :
MRALALSAVLMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENKQQGFTNDLKRANQAFLPASTFKIPNSLIA
LDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNLDSFWLDG
GIRISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANADYIIRAKTGYSVRIEPKIGWWVGWVELDDNVWFFATNMD
MPSAEGLGLRQSITKAVLKQEKIIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
bla OXA-10 CAJ77047.1 Oxacillinase Not tested AbaR1 Protein 3e-59 48
blaOXA-129 AET25386.1 OXA-129 beta-lactamase Not tested PAGI-2(C) Protein 6e-55 46
bla OXA-129 AFG30109.1 OXA-129 beta-lactamase Not tested PAGI-2 Protein 6e-55 46
blaOXA-2 YP_005176242.1 beta-lactamase OXA-2 protein Not tested ICEPmu1 Protein 3e-40 43
BJAB0715_00989 YP_008216137.1 Beta-lactamase class D Not tested AbaR27 Protein 9e-40 41
oxa23 AEO37447.1 class D beta-lactamase OXA-23 Not tested AbaR4 Protein 9e-40 41
oxa-23 AFV47968.1 class D beta-lactamase OXA-23 Not tested AbaR25 Protein 7e-40 41
oxa-23 AFV47996.1 class D beta-lactamase OXA-23 Not tested delta-AbaR25 Protein 7e-40 41
bla(Oxa-23) AFH57213.1 carbapenemase Not tested AbaR4b Protein 7e-40 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shewmr7_3328 YP_739367.1 Beta-lactamase JN205800.1.gene6.p01 Protein 1e-117 94
Shewmr7_3328 YP_739367.1 Beta-lactamase HM015773.1.gene6.p01 Protein 4e-117 92
Shewmr7_3328 YP_739367.1 Beta-lactamase AY500137.1.gene1.p01 Protein 4e-116 91
Shewmr7_3328 YP_739367.1 Beta-lactamase HQ700343.1.gene1.p01 Protein 2e-113 90
Shewmr7_3328 YP_739367.1 Beta-lactamase AY343493.1.gene1.p01 Protein 1e-72 59
Shewmr7_3328 YP_739367.1 Beta-lactamase U37105.2.gene2.p01 Protein 2e-59 48
Shewmr7_3328 YP_739367.1 Beta-lactamase NC_010410.6002874.p0 Protein 2e-59 48
Shewmr7_3328 YP_739367.1 Beta-lactamase X75562.1.gene1.p01 Protein 2e-56 47
Shewmr7_3328 YP_739367.1 Beta-lactamase AY445080.1.gene1.p01 Protein 1e-58 47
Shewmr7_3328 YP_739367.1 Beta-lactamase Z22590.1.gene1.p01 Protein 8e-59 47
Shewmr7_3328 YP_739367.1 Beta-lactamase U59183.1.gene3.p01 Protein 3e-59 47
Shewmr7_3328 YP_739367.1 Beta-lactamase AF231133.1.gene3.p01 Protein 6e-58 47
Shewmr7_3328 YP_739367.1 Beta-lactamase AM412777.1.gene1.p01 Protein 1e-58 47
Shewmr7_3328 YP_739367.1 Beta-lactamase AJ854182.1.gene1.p01 Protein 4e-59 47
Shewmr7_3328 YP_739367.1 Beta-lactamase X58272.1.gene1.p01 Protein 2e-55 46
Shewmr7_3328 YP_739367.1 Beta-lactamase AM932669.1.gene2.p01 Protein 4e-55 46
Shewmr7_3328 YP_739367.1 Beta-lactamase AF300985.1.gene1.p01 Protein 5e-39 44
Shewmr7_3328 YP_739367.1 Beta-lactamase AF350424.1.gene1.p01 Protein 1e-37 44
Shewmr7_3328 YP_739367.1 Beta-lactamase AY139598.1.gene3.p01 Protein 7e-41 44
Shewmr7_3328 YP_739367.1 Beta-lactamase AF317511.1.gene5.p01 Protein 7e-40 44
Shewmr7_3328 YP_739367.1 Beta-lactamase Y10693.2.gene1.p2 Protein 7e-41 44
Shewmr7_3328 YP_739367.1 Beta-lactamase L07945.1.gene1.p01 Protein 4e-41 44
Shewmr7_3328 YP_739367.1 Beta-lactamase DQ522237.1.gene5.p01 Protein 7e-41 44
Shewmr7_3328 YP_739367.1 Beta-lactamase AF315351.1.gene2.p01 Protein 6e-41 44
Shewmr7_3328 YP_739367.1 Beta-lactamase AF371964.1.gene1.p1 Protein 4e-40 43
Shewmr7_3328 YP_739367.1 Beta-lactamase JF800667.1.gene2.p01 Protein 1e-39 43
Shewmr7_3328 YP_739367.1 Beta-lactamase GQ202693.1.gene2.p01 Protein 1e-40 43
Shewmr7_3328 YP_739367.1 Beta-lactamase JF795487.1.gene1.p01 Protein 9e-40 43
Shewmr7_3328 YP_739367.1 Beta-lactamase EF552405.1.gene1.p01 Protein 3e-40 43
Shewmr7_3328 YP_739367.1 Beta-lactamase U63835.1.gene1.p01 Protein 2e-40 43
Shewmr7_3328 YP_739367.1 Beta-lactamase M95287.gene.p01 Protein 1e-40 43
Shewmr7_3328 YP_739367.1 Beta-lactamase AY289608.1.gene2.p01 Protein 7e-40 42
Shewmr7_3328 YP_739367.1 Beta-lactamase AY795964.gene.p01 Protein 4e-40 41
Shewmr7_3328 YP_739367.1 Beta-lactamase HM488989.1.gene1.p1 Protein 4e-40 41
Shewmr7_3328 YP_739367.1 Beta-lactamase NC_011586.7044972.p0 Protein 4e-40 41
Shewmr7_3328 YP_739367.1 Beta-lactamase HM488992.1.gene1.p1 Protein 1e-39 41
Shewmr7_3328 YP_739367.1 Beta-lactamase HM488988.1.gene1.p1 Protein 3e-40 41
Shewmr7_3328 YP_739367.1 Beta-lactamase HM488990.1.gene1.p1 Protein 3e-40 41
Shewmr7_3328 YP_739367.1 Beta-lactamase HM488991.1.gene1.p1 Protein 6e-40 41
Shewmr7_3328 YP_739367.1 Beta-lactamase AY423074.1.gene1.p01 Protein 7e-37 41