Gene Information

Name : lysS (Shewmr7_3196)
Accession : YP_739237.1
Strain : Shewanella sp. MR-7
Genome accession: NC_008322
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 3780865 - 3782367 bp
Length : 1503 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACTGAACAAGTACAAGATGAAAACAAACTGATTGCCGAGCGTCGTGCCAAGCTAGAAAGCATTCGCCCGAACTGCAG
CGCTAATGCTCACCCTAATACTTTCCGTCGCACCCACAAAGCGGCTGAGTTGCAGGAAAAATACGGTCAAAACACTAAGG
AAGAACTCGAAGCCTTAGGTTTTAAAACCAGCATCGCTGGCCGTATCATGGCAAAACGTGGCCCATTCCTGGTGATCCAA
GACGTGTCTGGTCGTATCCAAGCTTACGCTGAAAAGGGCGTTCAAGCGGATCTGAAAGACCGTTACCAAGGTTTGGATAT
CGGTGACATCATCGGCGTAACCGGTCAGTTACACTTGTCTGGTAAAGGCGATCTGTACGTGAACATGGAAGAGTACCAAC
TGCTGACCAAAGCACTGCGTCCTCTGCCAGAAAAATTCCACGGCCTGACCGACCAAGAAACTCGTTACCGCCAACGTTAT
GTGGACTTAATCGTTAACGAAGAATCTCGTCAAGCCTTCGTCATGCGTTCAAAAGTGGTTGCAGCTATCCGTAACTTCAT
GATCAAAAAAGAGTTCATGGAAGTTGAAACCCCAATGATGCACGTGATCCCAGGCGGCGCTTCAGCCCGTCCATTTATCA
CTCACCACAATGCGCTGGACATGCCAATGTACCTGCGTATCGCGCCAGAGTTATACCTCAAGCGTTTAGTGGTAGGTGGT
TTTGAGCGCGTGTTCGAAATCAACCGTAACTTCCGTAACGAAGGTCTGTCGCCACGCCATAACCCAGAATTCACTATGAT
GGAATTCTATATGGCCTATGCAGACTACAAAGATCTGATGGACTTAACCGAAGAACTGTTAAGCTCTATCGCGATTGAAC
TGTTAGGCAGCGCGCAAATGCCATACGGCGAGCACACTGTTGATTTCGGTGGCCCATATGCCCGTTTAAGCATGTTAGAA
GCGATTCAGAAGTACAATCCTGACAACGCAACTATCCAAGCCATGACCTACGAGCAAGTGAAAGATCTTGAATTCATGCG
TGAACTGGCTATCAGCCTAGGTATCAAGATCGAGAAGTTCTGGACCTGTGGTCAGCTATTAGAAGAAATCTTCGGTGAAA
CCGCTGAATGGCAGTTAATGCAACCGACTTTCATCACAGGCTACCCAGCGGACATTTCGCCACTGGCACGTCGTAACGAT
GACAATCACTTCATCACTGACCGTTTCGAATTCTTCATCGGTGGCCGTGAAGTGGCTAACGGTTTCAGCGAGTTAAACGA
TGCTGAAGACCAAGACAGCCGCTTTAAGGCGCAGGTTGATGCGAAAGACGCAGGTGACGACGAAGCCATGTTCTACGATG
CAGACTACATCACTGCACTGGAACACGGTTTACCACCAACAGCGGGTCAAGGTATCGGTATCGACCGTTTAGTGATGCTA
TTCACTAACACTCATACTATCCGTGACGTGATCCTGTTCCCAGCGATGCGCCCACAGGCCTAA

Protein sequence :
MTEQVQDENKLIAERRAKLESIRPNCSANAHPNTFRRTHKAAELQEKYGQNTKEELEALGFKTSIAGRIMAKRGPFLVIQ
DVSGRIQAYAEKGVQADLKDRYQGLDIGDIIGVTGQLHLSGKGDLYVNMEEYQLLTKALRPLPEKFHGLTDQETRYRQRY
VDLIVNEESRQAFVMRSKVVAAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGG
FERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEELLSSIAIELLGSAQMPYGEHTVDFGGPYARLSMLE
AIQKYNPDNATIQAMTYEQVKDLEFMRELAISLGIKIEKFWTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRND
DNHFITDRFEFFIGGREVANGFSELNDAEDQDSRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVML
FTNTHTIRDVILFPAMRPQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-130 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_739237.1 lysyl-tRNA synthetase VFG1668 Protein 2e-130 57