Gene Information

Name : Shewmr7_2127 (Shewmr7_2127)
Accession : YP_738172.1
Strain : Shewanella sp. MR-7
Genome accession: NC_008322
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2516692 - 2517429 bp
Length : 738 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAATGTGACTCTGTTAATCCCGGCGCGTTACGGTTCAAGCCGCTTCCCGGGCAAGCCCTTAGCCCCGATTAACGGCAA
GCCGATGATCCAACACGTGTACGAACGCGCGTCGTTAGCCAAAGGCCTCACCAATATTTATGTTGCAACCGATGATGAGC
GTATCAAAAGCGCCGTAGAAGGCTTCGGTGGCAAAGTGGTCATGACCAGCCCTGATGCGGCATCGGGCACAGACCGTATC
AATGATGCGATTAACCAATTAGGTTTGAAGGATGACGATCTGGTCATCAACCTTCAAGGCGACCAACCCCTAATCGACCC
GACTTCCATCGAGCAAGTGATCAGCCTCTTCGAACGTCATCCAGGCGAGTTTGAAATGGCGACCCTCGGCTATGAAATTG
TCAACAAAGCCGAACTCGACGATCCTATGCATGTGAAGATGGTATTCGATAACGACTACTACGCGCTGTATTTCTCCCGC
GCACGTATTCCCTTCGGCCGCGATACCAAAGATTATCCAGTTTACAAGCACTTAGGCGTGTATGCTTACACCCGCAGATT
CGTGCAAGCCTTCGCCGCCCTCCCCTTAGGTCGTCTCGAAGATCTGGAAAAATTAGAGCAGCTACGCGCCCTAGAACATG
GCCATAAGATCAAAGTCGCCATCAGCGCCTTCGACTCAATCGAAGTTGACACGCCAGAAGATATTCGTAAGTGTGAGCAG
CGTTTAGCCGTTGATTAA

Protein sequence :
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKSAVEGFGGKVVMTSPDAASGTDRI
NDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGYEIVNKAELDDPMHVKMVFDNDYYALYFSR
ARIPFGRDTKDYPVYKHLGVYAYTRRFVQAFAALPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSIEVDTPEDIRKCEQ
RLAVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 5e-41 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-41 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-41 41