Gene Information

Name : guaA (Shewmr7_1306)
Accession : YP_737362.1
Strain : Shewanella sp. MR-7
Genome accession: NC_008322
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1513716 - 1515293 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCGATATTCATGAGCATAAGATACTGATCCTCGATTTTGGATCTCAGTACACCCAACTGATTGCCCGTCGTATCCG
TGAAATTGGTGTTTACTGTGAGCTATGGGCATGGGATGTGACCGAAGCCCAAATCCGTGAGTTTGCCCCTAACGGTATTA
TCCTCGCTGGCGGCCCTGAAAGTGTCACCGCCGACAACTCTCCCCGCGCACCTGAATATGTGTTCAATGCTGGCGTGCCC
GTCCTCGGTATCTGCTACGGCATGCAAACCATGTCTGAGCAGCTCGGCGGTAAAGTGATCCAAGGTGTGGGTGAAGGCGA
ATTCGGTTATGCACAAATCGAAATGTTAGCGCAATCGGCCCTGTTCAAAGACATCGAAGATGCAGTTAACAGCGATGGCA
AGTCTCTGCTCGATGTGTGGATGAGCCATGGCGATAAAGTTTCGGCGATCCCAGAAGGTTTTGTGGCCGTTGCTAAAACT
GACACTTGCCCATTTGCGGCCATGTCTTGTGAGGAAAAACGTTTCTACGGCGTTCAGTTCCACCCTGAAGTAACCCATAC
CCGCCAAGGTATGCGTATGCTGTCGCACTTTGCCTTAGATATCTGTGGTTGTGCGGCCAACTGGAAACCTTCTTCAATCA
TCGAAGACGCAATCGAGCGCTTGAAAAAGCAAGTGGGCGACGATGAAGTGATTTTAGGTCTGTCTGGTGGTGTGGATTCA
TCGGTAGTGGCCATGTTGCTGCACCGCGCAATTGGCAAAAAACTGACCTGCGTATTCGTTGATAACGGCTTACTGCGTTT
AAACGAAGCGAAGCAAGTCATGGAAATGTTTGGTGACCATTTCGGCCTGAACATTGTACACATCGATGCGGAAAACCGCT
TCCTCGACGCGCTGAAAGGCGAAGCCGATCCAGAAGCGAAACGTAAAATCATCGGCCGTGTATTCGTTGAAATCTTCGAC
GAAGAAGCCAAGAAATGCGTTAACGCTAAATGGTTAGCCCAAGGCACCATCTACCCAGACGTGATTGAATCTGCGGGCAG
CGCCACAGGTAAAGCCCATGTGATTAAGTCGCACCATAACGTTGGCGGTCTGCCAGACGATATGGAGTTAGGTCTGGTGG
AGCCACTGCGCGAACTCTTTAAAGATGAAGTGCGTAAGATTGGCCTCGAGCTAGGTCTGCCATACAACATGCTTTACCGC
CACCCGTTCCCAGGTCCTGGTTTAGGCGTACGAGTACTGGGTGAAGTGAAGAAAGAATACTGTGATTTGCTGCGCCGCGC
CGATGCCATTTTCATCGAAGAGCTGCACAAAGCTGATCTTTATAACAAAGTCAGCCAAGCCTTTACCGTGTTCTTACCCG
TTCGCTCTGTCGGTGTGATGGGCGATGGCCGTAAATACGATTGGGTGGTGTCACTGCGCGCCGTTGAAACCATCGACTTT
ATGACCGCTCACTGGGCGCACTTGCCATACGATTTCTTAGGCCGTGTGTCTAACCGTATCATCAACGAAATCGACGGTAT
CTCCCGTGTGGTTTACGATATTTCAGGGAAGCCACCTGCGACTATCGAGTGGGAATAA

Protein sequence :
MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTADNSPRAPEYVFNAGVP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLAQSALFKDIEDAVNSDGKSLLDVWMSHGDKVSAIPEGFVAVAKT
DTCPFAAMSCEEKRFYGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQVGDDEVILGLSGGVDS
SVVAMLLHRAIGKKLTCVFVDNGLLRLNEAKQVMEMFGDHFGLNIVHIDAENRFLDALKGEADPEAKRKIIGRVFVEIFD
EEAKKCVNAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-123 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-123 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-124 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-112 48