Gene Information

Name : Shewmr4_0694 (Shewmr4_0694)
Accession : YP_732831.1
Strain : Shewanella sp. MR-4
Genome accession: NC_008321
Putative virulence/resistance : Resistance
Product : Beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2602
EC number : 3.5.2.6
Position : 801850 - 802647 bp
Length : 798 bp
Strand : +
Note : PFAM: penicillin-binding protein, transpeptidase; KEGG: son:SO0837 beta-lactamase, putative

DNA sequence :
ATGCGTGCGTTAGCCTTATCGGCTGTGTTGATGGTGACAACGATGATTGGCATGCCTGCGGTGGCAAAGGAGTGGCAAGA
GAACAAGAGCTGGAATGCTCACTTTAGCGAACATAAAACCCAAGGCGTGGTTGTGCTCTGGAACGAGAATACACAGCAGG
GTTTTACTAACGATCTTAAACGGGCAAACCAAGCATTTTTACCGGCATCGACCTTTAAGATCCCAAACAGTTTAATTGCC
TTGGACTTAGGTGTGGTTAAGGATGAGCATCAGGTCTTTAAATGGGATGGACAGACGCGAGATATCGCCGCATGGAATCG
TGACCATGATTTAATCACCGCGATGAAGTATTCGGTTGTGCCTGTTTATCAAGAATTTGCCCGCCAAATTGGCGAGGCTC
GTATGAATAAAATGCTGCACGCCTTCGATTATGGCAATGAGGATATCTCGGGCAATTTGGACAGTTTTTGGCTCGATGGT
GGTATTCGCATTTCGGCTACCCAGCAAATCGCTTTTTTACGCAAGCTGTACCACAACAAGCTGCACGTTTCTGAGCGTAG
TCAGCGCATCGTGAAACAAGCCATGCTGACCGAGGCAAATGCCGACTATATCATCCGAGCGAAAACCGGCTATTCGGTCA
GAATTGAACCGAAAATCGGTTGGTGGGTTGGCTGGGTCGAACTGGATGATAATGTGTGGTTTTTCGCGACCAATATGGAT
ATGCCTTCCGCTGAGGGCTTAGGGTTACGTCAAAGCATTACGAAAGCAGTGCTGAAACAGGAAAAAATTATTCCTTAG

Protein sequence :
MRALALSAVLMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENTQQGFTNDLKRANQAFLPASTFKIPNSLIA
LDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVVPVYQEFARQIGEARMNKMLHAFDYGNEDISGNLDSFWLDG
GIRISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANADYIIRAKTGYSVRIEPKIGWWVGWVELDDNVWFFATNMD
MPSAEGLGLRQSITKAVLKQEKIIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
bla OXA-10 CAJ77047.1 Oxacillinase Not tested AbaR1 Protein 1e-59 48
blaOXA-129 AET25386.1 OXA-129 beta-lactamase Not tested PAGI-2(C) Protein 3e-55 46
bla OXA-129 AFG30109.1 OXA-129 beta-lactamase Not tested PAGI-2 Protein 3e-55 46
blaOXA-2 YP_005176242.1 beta-lactamase OXA-2 protein Not tested ICEPmu1 Protein 6e-40 43
ACICU_00226 YP_001844885.1 Beta-lactamase class D Not tested AbaR20 Protein 3e-41 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shewmr4_0694 YP_732831.1 Beta-lactamase JN205800.1.gene6.p01 Protein 4e-117 93
Shewmr4_0694 YP_732831.1 Beta-lactamase HM015773.1.gene6.p01 Protein 1e-116 91
Shewmr4_0694 YP_732831.1 Beta-lactamase HQ700343.1.gene1.p01 Protein 7e-113 90
Shewmr4_0694 YP_732831.1 Beta-lactamase AY500137.1.gene1.p01 Protein 1e-115 90
Shewmr4_0694 YP_732831.1 Beta-lactamase AY343493.1.gene1.p01 Protein 3e-72 59
Shewmr4_0694 YP_732831.1 Beta-lactamase U37105.2.gene2.p01 Protein 8e-60 48
Shewmr4_0694 YP_732831.1 Beta-lactamase NC_010410.6002874.p0 Protein 8e-60 48
Shewmr4_0694 YP_732831.1 Beta-lactamase X75562.1.gene1.p01 Protein 1e-56 47
Shewmr4_0694 YP_732831.1 Beta-lactamase AJ854182.1.gene1.p01 Protein 2e-59 47
Shewmr4_0694 YP_732831.1 Beta-lactamase AY445080.1.gene1.p01 Protein 6e-59 47
Shewmr4_0694 YP_732831.1 Beta-lactamase Z22590.1.gene1.p01 Protein 3e-59 47
Shewmr4_0694 YP_732831.1 Beta-lactamase U59183.1.gene3.p01 Protein 1e-59 47
Shewmr4_0694 YP_732831.1 Beta-lactamase AF231133.1.gene3.p01 Protein 2e-58 47
Shewmr4_0694 YP_732831.1 Beta-lactamase AM412777.1.gene1.p01 Protein 5e-59 47
Shewmr4_0694 YP_732831.1 Beta-lactamase AM932669.1.gene2.p01 Protein 2e-55 46
Shewmr4_0694 YP_732831.1 Beta-lactamase X58272.1.gene1.p01 Protein 1e-55 46
Shewmr4_0694 YP_732831.1 Beta-lactamase AF300985.1.gene1.p01 Protein 1e-38 44
Shewmr4_0694 YP_732831.1 Beta-lactamase AF350424.1.gene1.p01 Protein 3e-37 44
Shewmr4_0694 YP_732831.1 Beta-lactamase AY139598.1.gene3.p01 Protein 9e-41 44
Shewmr4_0694 YP_732831.1 Beta-lactamase JF800667.1.gene2.p01 Protein 3e-39 44
Shewmr4_0694 YP_732831.1 Beta-lactamase AF317511.1.gene5.p01 Protein 1e-39 44
Shewmr4_0694 YP_732831.1 Beta-lactamase Y10693.2.gene1.p2 Protein 2e-40 44
Shewmr4_0694 YP_732831.1 Beta-lactamase L07945.1.gene1.p01 Protein 1e-40 44
Shewmr4_0694 YP_732831.1 Beta-lactamase DQ522237.1.gene5.p01 Protein 2e-40 44
Shewmr4_0694 YP_732831.1 Beta-lactamase AF315351.1.gene2.p01 Protein 2e-40 44
Shewmr4_0694 YP_732831.1 Beta-lactamase AF371964.1.gene1.p1 Protein 5e-40 43
Shewmr4_0694 YP_732831.1 Beta-lactamase M95287.gene.p01 Protein 3e-40 43
Shewmr4_0694 YP_732831.1 Beta-lactamase JF795487.1.gene1.p01 Protein 2e-39 43
Shewmr4_0694 YP_732831.1 Beta-lactamase U63835.1.gene1.p01 Protein 5e-40 43
Shewmr4_0694 YP_732831.1 Beta-lactamase GQ202693.1.gene2.p01 Protein 3e-40 43
Shewmr4_0694 YP_732831.1 Beta-lactamase EF552405.1.gene1.p01 Protein 7e-40 43
Shewmr4_0694 YP_732831.1 Beta-lactamase AY289608.1.gene2.p01 Protein 1e-39 43
Shewmr4_0694 YP_732831.1 Beta-lactamase AF024602.1.gene3.p01 Protein 1e-41 41
Shewmr4_0694 YP_732831.1 Beta-lactamase AY423074.1.gene1.p01 Protein 4e-37 41