Gene Information

Name : Shewmr4_3402 (Shewmr4_3402)
Accession : YP_735525.1
Strain : Shewanella sp. MR-4
Genome accession: NC_008321
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 4061041 - 4064130 bp
Length : 3090 bp
Strand : +
Note : PFAM: acriflavin resistance protein; KEGG: ppr:PBPRA2318 hypothetical transporter, AcrB/D/F family

DNA sequence :
ATGAATATTGCAGAGTATTCTATCCGCCACAAAGTCATCAGTTGGATGTTTGTATTGCTGCTACTTGTCGGTGGTGGCGT
GAGTTTTACGGGTCTTGGACAATTAGAATTTCCCGAATTTACCATTAAAGAAGCCCTAGTGATCACCGCCTATCCAGGTG
CGTCACCGGAGCAAGTGGAAGAAGAAGTTACCCTTCCCCTCGAAGATGCCTTGCAACAACTCGATGCGGTGAAACATGTC
ACCTCAATCAACAGTGCGGGCCTGTCGCAGATCCAAATTGAGATTAAAGAAAATTACGATAAAACCAGCCTGCCTCAGGT
ATGGGATGAAGTGCGTCGTAAGGTCAACGACACCGCAGGGCAATTGCCTCCCGGTACCAGTACGCCCAAGGTATTTGACG
ACTTTGGCGATGTCTACGGCATTTTATTTAACCTGTCAGGCCCCGATTATAGCAACCGCGAATTAAGCAATTATGCGGAC
TATTTACGCCGCGAAATCGTGCTGGTACCCGGCGTGAAAAAAGTCTCAGTGGCGGGCAGCGTCACCGAGCAAGTTGTGAT
TGAAATTTCCCAACAAAGACTCTCGGCACTGGGACTAGACCAAAGCTATATCTACGGCTTGATCAACAACCAAAACGTAG
TCTCCAATGCAGGCAGTTTAGTGGTTGGCGATAATCGCATTCGTATCCATCCCACCGGGGAATTTAGCAGTGTGCAGGAT
CTGGCGCGTCTGATCGTCAGCCCGCCCGGTAGCACCGAACTTATCTATCTTGGTGACATTGCCAATATAGAAAAAGATTA
CGATGAAACCCCGGATGTGCTCTATCACAACCGTGGCGAGACGGCTTTATCACTGGGGATTTCCTTCTCTAGCGGTGTTA
ACGTGGTTGAAGTCGGTAAAAGTGTGAGTCAGCGCCTTGCCGAGCTGGAGTCACAGCGCCCGATTGGAATGAACCTAGAC
ACGGTTTATAACCAGAGCCTGGCGGTAGATGACACTGTTAACGGCTTTTTAATCAACCTATTAGAATCCATCGCCATCGT
TATTGCCGTACTCCTGCTGTTTATGGGTTTACGCTCAGGTTTATTGATGGGCTTAATCCTGCTGCTCACCATTCTCGGCA
CCTTTATCGTGATGAAAGTGCTGGGTATTGAGCTGCAACTTATCTCCCTCGGCGCATTGATTATCGCCCTAGGTATGCTG
GTCGATAACGCCATTGTAGTGACAGAAGGCATTTTGATTGGCCTGCGTCGTGGTAAGACTCGCCTCGAAGCCGCCAAGCA
AATTGTGTCGCAAACCCAATGGCCACTGCTTGGCGCCACCGTTATCGCGATTATCGCCTTTGCGCCAATTGGTTTATCAC
AAAATGCCGCGGGAGAATTTTGTCGTTCACTGTTCCAAGTGTTAATGATCTCTTTATTTATCAGTTGGATTACCGCAATC
ACCCTAACGCCCTTCTTCTGCCATTTGCTGTTTAAAGATGCGCCAGCCGATGATGAAGAAGAACAGGATCCCTACAAGGG
TTGGTTCTTTAGCCTATACCGCGTGAGTTTGACCTTTGCCCTACGTTTTAGACTCGCCAGCATTGTATTGGTCGGCGTCA
TGCTCGTTAGCGCCGTGATTGGCTTTGGTCATATCAAAAATGTGTTCTTCCCCGCGTCGAATACACCAATCTTCTTTGTG
GATATTTGGATGCCCGAAGGCACTGATATCAAAGGTACCGAGCGTTTTACCGCCGATATTGAAAAGCTGTTACTCAAGCA
AGCCGAGGAGCAACACAGCGGCCTAAAACACTTAACCTCAGTGATCGGTCAAGGTGCGCAGCGCTTTATCCTGCCCTATC
AACCCGAAAAGGGTTATCCAGCCTATGCGCAGCTGATTATCGAGATGGAGGATCTAGCGTCGCTCAAAGTCTATATGCCA
GAGTTAGAAACCCTGTTAAATCAACGATTCCCACAGGCGCAATATCGATTCAAGAATATGGAAAACGGCCCTTCTCCGGC
CGCGAAGATTGAAGCACGCTTCTACGGCGATGATCCTGAGGTGCTGCGTGCGCTGGGCGCACAGGCCGAAGCTATCTTCA
ATGCAGAGCCGAGTATGGACGGTATTCGCCATGACTGGCGCAATCAAGTGCCCTTGATCCGCCCGCAACTGGAAAACGCC
CAAGCGAGGGAGACAGGGATCAGTAAGCAAGATCTGGATAATGCGCTGCTGATTAACTTTAGCGGTAAACAAATCGGGCT
TTACCGTGAAACCAGTCATTTGCTGCCCATAGTTGCGCGCGCTCCAGCCGAAGAGCGTTTACAGGCGGACAGCCTGTGGA
AGCTGCAAATTTGGAGCACCGAGCACAATACCTTTGTGCCAGCCACACAAGTGGTCAGTCAGTTTGAGACCCAGTGGGAA
AATCCATTGGTAAAACGTCGCGACCGGATGCGGATGTTAGCGGTACTGGCCGATCCTAAGCTTGGCAGCGATGAAACCGC
CGATTCTGTACTACACAAAGTAAAAGATAAGGTTGAAGCCATCAGCTTGCCAACGGGCTACCACTTAGAGTGGGGCGGCG
AGTATGAGACAGCAGGTGAAGCGCAAACGGCGGTATTTAGCTCGATTCCTATGGGTTATTTAGTGATGTTTTTAATCACA
GTATTCCTATTTAACTCTGTGCGTCAGCCCTTAGTGATTTGGTTTACCGTGCCACTCGCCTTGATTGGGGTGTCAGCCGG
ACTCCTGTTATTCGATGCTCCCTTTAGCTTTATGGCGCTGCTGGGCCTACTGAGTCTCTCGGGCATGGTGATTAAAAATG
GCATTGTGTTGGTCGATCAGATCAACCTAGAGCTCGGTGAAGGTAAACCCGCCTACGCCGCCCTTGTCGATTCGAGCGTG
AGTCGTGTGCGCCCAGTGTTAATGGCGGCGATCACCACAATGCTCGGGATGATACCGCTGATCCCCGATGCCTTTTTCGG
CTCCATGGCGATCACTATCATCTTTGGTTTAGGTTTTGCCTCATTGCTGACGCTTATCGTGCTGCCAGTGATGTACAGCT
TAGCCTTCAATATCAAACCGAATGCAGTAGCTGGTGCAGTCAACAACTAG

Protein sequence :
MNIAEYSIRHKVISWMFVLLLLVGGGVSFTGLGQLEFPEFTIKEALVITAYPGASPEQVEEEVTLPLEDALQQLDAVKHV
TSINSAGLSQIQIEIKENYDKTSLPQVWDEVRRKVNDTAGQLPPGTSTPKVFDDFGDVYGILFNLSGPDYSNRELSNYAD
YLRREIVLVPGVKKVSVAGSVTEQVVIEISQQRLSALGLDQSYIYGLINNQNVVSNAGSLVVGDNRIRIHPTGEFSSVQD
LARLIVSPPGSTELIYLGDIANIEKDYDETPDVLYHNRGETALSLGISFSSGVNVVEVGKSVSQRLAELESQRPIGMNLD
TVYNQSLAVDDTVNGFLINLLESIAIVIAVLLLFMGLRSGLLMGLILLLTILGTFIVMKVLGIELQLISLGALIIALGML
VDNAIVVTEGILIGLRRGKTRLEAAKQIVSQTQWPLLGATVIAIIAFAPIGLSQNAAGEFCRSLFQVLMISLFISWITAI
TLTPFFCHLLFKDAPADDEEEQDPYKGWFFSLYRVSLTFALRFRLASIVLVGVMLVSAVIGFGHIKNVFFPASNTPIFFV
DIWMPEGTDIKGTERFTADIEKLLLKQAEEQHSGLKHLTSVIGQGAQRFILPYQPEKGYPAYAQLIIEMEDLASLKVYMP
ELETLLNQRFPQAQYRFKNMENGPSPAAKIEARFYGDDPEVLRALGAQAEAIFNAEPSMDGIRHDWRNQVPLIRPQLENA
QARETGISKQDLDNALLINFSGKQIGLYRETSHLLPIVARAPAEERLQADSLWKLQIWSTEHNTFVPATQVVSQFETQWE
NPLVKRRDRMRMLAVLADPKLGSDETADSVLHKVKDKVEAISLPTGYHLEWGGEYETAGEAQTAVFSSIPMGYLVMFLIT
VFLFNSVRQPLVIWFTVPLALIGVSAGLLLFDAPFSFMALLGLLSLSGMVIKNGIVLVDQINLELGEGKPAYAALVDSSV
SRVRPVLMAAITTMLGMIPLIPDAFFGSMAITIIFGLGFASLLTLIVLPVMYSLAFNIKPNAVAGAVNN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 4e-177 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shewmr4_3402 YP_735525.1 acriflavin resistance protein BAC0428 Protein 0.0 54
Shewmr4_3402 YP_735525.1 acriflavin resistance protein BAC0519 Protein 0.0 54
Shewmr4_3402 YP_735525.1 acriflavin resistance protein BAC0526 Protein 0.0 53
Shewmr4_3402 YP_735525.1 acriflavin resistance protein BAC0425 Protein 2e-177 42