Gene Information

Name : Shewmr4_3248 (Shewmr4_3248)
Accession : YP_735373.1
Strain : Shewanella sp. MR-4
Genome accession: NC_008321
Putative virulence/resistance : Unknown
Product : primary replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 3879320 - 3880726 bp
Length : 1407 bp
Strand : -
Note : KEGG: son:SO3917 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase

DNA sequence :
ATGTCACAACAAGGTGCTTTTAAGCCTAAGAGTAAGCCGAGGGATTTGCAGGTCGATAGCCTCAAGCTGCCGCCGCATTC
AATAGAGGCTGAACAATCGGTATTAGGCGGCCTCATGTTAGACGCCGACGCTTGGGATAAAGTGGCCGAAACCGTAGTGA
AAGAGGATTTTTATTCCCGCTCACACAGGATGATTTTTGCGGCGATGCACCGTTTAGTTGAAACGGGTCAACCTATCGAC
TTAATCACGGTTTCTGAACAGCTTGAACTTGAAAATCAACTCGAAGAAGCGGGCGGCTTTGCCTACTTAGGCGAGATTGC
CAAAAACACCCCGAGCGCCGGTAACATTGTTTCCTACGCTGAGATTGTGCGCGAGCGCGCCGTGGTGCGGGAGATGATCC
GCGTTGCCCATGAGATTGCCGATGCGGGTTACAATCCCGAAGGGCGTGACTCCAGCGCCTTGCTCGACTTGGCCGAGAGT
AAAGTCTTTAAGATTGCCGAGCAGCGCACCAATGCCAACGAAGGTCCCGAAGGCATTAAAACCATTCTCGAAAAAACCGT
CGATAAGATTGAGCAGCTCTACAACAACCCGCATAACGGTGTGACAGGGGTGTCGAGCGGTTTTAGCGATCTCGACCGTA
TGACAGCGGGCTTCCAATCCGGCGACTTGATCATCGTCGCGGCGCGTCCTTCTATGGGTAAAACCACTTTCGCGATGAAC
CTCTGCGAGCAGGCGGCGATGAATGAAGACAAGCCTGTGCTGATTTTCAGTCTCGAGATGCCCTCGGAACAGATCATGAT
GCGTATGTTGGCCTCCTTGGGCCGCGTCGACCAAACTAAAATCCGTACCGGACAGCTCGATGATGAGGATTGGGCGCGGG
TATCCTCGACCATGGGGATCATGCTCGAGCAGGGCAAGATGTATATCGACGACGGTTCTGGCTTAACCCCGACCGAAGTG
CGCAGCCGTGCCCGCCGTATCGCCCGTGAACATGGCGGCTTATCGATGATCATGGTCGACTACTTGCAGCTGATGCAAGT
ACCGGCGTTATCGGACAACCGTACCCTAGAAATTGCCGAAATTTCTCGCTCTCTCAAGGCATTGGCTAAAGAGTTAGAGA
TCCCCGTTATTGCACTTTCCCAGCTTAACCGCTCACTCGAACAACGTGCCGATAAGCGCCCTGTGAACTCGGACTTACGT
GAATCGGGTTCTATTGAGCAGGATGCGGACCTCATCATGTTTATTTACCGTGATGAGGTGTATAACAACGATTCTCCCGA
TAAGGGCACGGCGGAAATCATCATAGGTAAGCAGCGTAACGGCCCAATCGGACGTGTGCGCTTGACCTTCCAAGGCCAGT
TTTCCCGTTTTGATAACTACGCTGGCCCGCAGTTTGAAGAAGATTAA

Protein sequence :
MSQQGAFKPKSKPRDLQVDSLKLPPHSIEAEQSVLGGLMLDADAWDKVAETVVKEDFYSRSHRMIFAAMHRLVETGQPID
LITVSEQLELENQLEEAGGFAYLGEIAKNTPSAGNIVSYAEIVRERAVVREMIRVAHEIADAGYNPEGRDSSALLDLAES
KVFKIAEQRTNANEGPEGIKTILEKTVDKIEQLYNNPHNGVTGVSSGFSDLDRMTAGFQSGDLIIVAARPSMGKTTFAMN
LCEQAAMNEDKPVLIFSLEMPSEQIMMRMLASLGRVDQTKIRTGQLDDEDWARVSSTMGIMLEQGKMYIDDGSGLTPTEV
RSRARRIAREHGGLSMIMVDYLQLMQVPALSDNRTLEIAEISRSLKALAKELEIPVIALSQLNRSLEQRADKRPVNSDLR
ESGSIEQDADLIMFIYRDEVYNNDSPDKGTAEIIIGKQRNGPIGRVRLTFQGQFSRFDNYAGPQFEED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 1e-97 52
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 4e-101 52
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 1e-101 52
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 5e-101 50
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 4e-102 50
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 3e-92 49
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 3e-92 49
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 9e-85 46
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 2e-81 45