Gene Information

Name : alr (Shewmr4_3247)
Accession : YP_735372.1
Strain : Shewanella sp. MR-4
Genome accession: NC_008321
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 3878168 - 3879244 bp
Length : 1077 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
TTGAAACCTTTTCCCCGAGCAGAAATTAGCAGTAGTGCACTGCAAAACAATCTCGCCGTCTTGCGTCAACAGGCGAGTCG
CAGCCAAGTGATGGCTGTGGTGAAAGCCAATGGTTATGGTCATGGATTATTAAATGTCGCCAACTGTTTACACACTGCCG
ATGGCTTTGGTCTAGCCCGTTTAGAAGAGGCCTTAGAGCTGCGCGCCGGTGGCGTGAAGGCGCGCTTGTTATTGCTTGAA
GGCTTCTTTCGTAGCACTGATTTACCTTTGTTGGTGGCCCACGATATCGATACTGTGGTGCACCATGAGTCTCAAATCGA
GATGTTAGAGCAGGCGACGCTATCAAAACCTGTCACCGTATGGTTGAAAGTGGATTCTGGCATGCATCGTTTAGGCGTGA
CGCCTGAGCAATTTGCGCAGGTGTATGCGCGTTTGACGGCCTGTGACAATGTTGCCAAGCCCATACATTTGATGACTCAC
TTTGCCTGTGCCGATGAGCCTGAAAATCATTACACCCAAGTGCAAATGCAAACCTTTAACCAGTTAACCGCGGATTTGCC
TGGATTTAGAACCTTAGCCAATTCTGCGGGCGCCCTCTATTGGCCCAAAAGCCAAGGGGATTGGATCCGCCCTGGAATCG
CACTCTATGGTGTGTCTCCCGTTACGGGGGATTGCGGCGCCAATCATGGTCTGATCCCGGCGATGAACTTAGTCTCGCGT
TTGATTGCGGTGCGCGATCACAAAGCGGGACAACCCGTAGGTTATGGTTGTTATTGGACGGCGAAGCAAGATACTCGCCT
TGGTGTCGTGGCCATTGGTTACGGCGATGGTTATCCGCGCAATGCACCAGAAGGCACGCCTGTGTGGGTGAATGGTCGCC
GAGTGCCGATTGTTGGTCGTGTCTCTATGGATATGTTAACCGTTGATTTAGGCGCCGATGCGACAGACCTTGTGGGCGAT
GAAGCCCTGCTCTGGGGCGCAGCCTTGCCCGTTGAGGAAGTCGCCGAACACATTGGCACTATCGCCTATGAGCTAGTGAC
CAAACTTACCCCAAGGGTCGCTGTGTGTCTTGCATAA

Protein sequence :
MKPFPRAEISSSALQNNLAVLRQQASRSQVMAVVKANGYGHGLLNVANCLHTADGFGLARLEEALELRAGGVKARLLLLE
GFFRSTDLPLLVAHDIDTVVHHESQIEMLEQATLSKPVTVWLKVDSGMHRLGVTPEQFAQVYARLTACDNVAKPIHLMTH
FACADEPENHYTQVQMQTFNQLTADLPGFRTLANSAGALYWPKSQGDWIRPGIALYGVSPVTGDCGANHGLIPAMNLVSR
LIAVRDHKAGQPVGYGCYWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGADATDLVGD
EALLWGAALPVEEVAEHIGTIAYELVTKLTPRVAVCLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 3e-54 44