Gene Information

Name : cvrA; nhaP2; ycgO (Shewmr4_3088)
Accession : YP_735216.1
Strain : Shewanella sp. MR-4
Genome accession: NC_008321
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 3692917 - 3694641 bp
Length : 1725 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
GTGGATGCAGATTCCATCAATAGTTTTTTTCTGATCGGTGCCTTGCTTGCCGCTGTGAGTGTTTTGTTAAGTCCCGTGTC
TTCGCGCTTGGGTATCCCTATCTTATTAATTTTCCTCGCTGTAGGGATTTTAGCGGGGGAAGATGGTCCCGGCGGCATTC
TGTTTGATGACTACTCAACCGCTTATCTTGTCAGTAACTTAGCCTTAGCCATTATCTTGCTCGATGGCGGTATGCGCACG
CGGGTCGCGAGCTTTAGGGTGGCACTGTGGCCAGCATTATCGTTGGCGACCTTCGGAGTCGCTATCACCACCAGTATCAC
TGGTGTGATGGCCGCATGGTTATTCGATTTGCATTGGCTGCAGGGGTTGCTGGTGGGAGCTATTGTCGGCTCCACCGATG
CGGCGGCGGTATTTTCACTATTAAAGGGACGCAGCTTAAACGAGCGTGTTGGCGCGACGCTGGAAATCGAATCGGGCAGC
AACGACCCTATGGCGGTATTTTTAACCGTGACCCTGATTGCCATCCTAGGCAATGTGGACGCCGAGCTATCCGCAAGCTT
TATGCTGATAAGCTTTATCAAGCAGTTTGGCTTGGGGATTTTCCTCGGCCTCGGTGGCGGCTGGTTGCTGTGGAAGTTGG
TGAATTTAAGCAAGCTTGCCGAAGGCTTGTATTCGATTTTAGTGCTCAGTGGCGGCCTGATGATTTACGCCGCGTCGAAC
AAACTTGGTGGCAGTGGCATTCTGTCAATTTACTTAGTTGGTTTATTCCTTGGCAACAAGCCCACCCGTGGTCGCCATTC
AATCTTAAACGTGTTGGATGGCATGACCTGGGTTAGTCAAATCGGTATGTTCCTCGTATTAGGCTTGCTGCTCACACCGT
CTGACTTGTTGGACATTTGGCTGCCGGGCTTGGCATTAGCCTTTGGGATGATCCTGTTTGCCAGACCGTTAGCCGTATGG
CTCAGCTTGCTACCTTTTAAGAGTTTTAGCAGTCGTGACCGCTGGTTTATCTCTTGGGTCGGGCTTCGCGGCGCCGTGCC
GATTATTTTAGCGGTATTCCCTATGATGGCGGGATTACCGGGCGCTCAGTTGTACTTTAACTTGGCGTTTTTTGTGGTGT
TAGTGTCGCTGTTAGTGCAAGGGGCGTCACTTACCACTGCGGCGCGTTTAGCCAAGGTCGAATTACCGCCTAAGCCATTA
CCTATTTCACGCTCTGGGGTCGAAATTTACCCTAGCAGCGAGTGGGAAGTGTTTGTTTATCGGTTGAGTGAAAACAAATG
GTGCATTGGCGAGCCGCTTAAACGTCTTTCTATGCCTGATGGCACGCGGATTGCGGCGGTATTTCGCCATAACACACTGT
TGCACCCATCGGGCAGCACCTGTCTCGAAGCGGGAGATATTTTGTGCGTGCTAGGACAAGAAAAGAGTCTAGAGGCTTTG
AGTAACCTCTTTAGTCAGGCGCCTGAAACCAAGGAAGTACCACGTTTCTTCGGGGACTTCTTTATCGATACCGAGGTTAA
GCTGCTGGATCTGGCGCCAATTTATGGTCTGGAGTTAGACGAAGCAACCGGTGATATGACTGTCGCAGATTTAGTGGCGG
CAGAATTAGGTTCACATCCGGTACTTGGGGATCAGTTCCTGTGGCAGTCACTGCATTGGGTGGTCGCAGGGCTTTATGAA
GGCAAAGTCACCAATGTGGGTATTCGCTTACCAGCTGAGGCGTAA

Protein sequence :
MDADSINSFFLIGALLAAVSVLLSPVSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGVMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILGNVDAELSASFMLISFIKQFGLGIFLGLGGGWLLWKLVNLSKLAEGLYSILVLSGGLMIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHSILNVLDGMTWVSQIGMFLVLGLLLTPSDLLDIWLPGLALAFGMILFARPLAVW
LSLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PISRSGVEIYPSSEWEVFVYRLSENKWCIGEPLKRLSMPDGTRIAAVFRHNTLLHPSGSTCLEAGDILCVLGQEKSLEAL
SNLFSQAPETKEVPRFFGDFFIDTEVKLLDLAPIYGLELDEATGDMTVADLVAAELGSHPVLGDQFLWQSLHWVVAGLYE
GKVTNVGIRLPAEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 1e-115 59
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 1e-115 59