Gene Information

Name : Shewmr4_2477 (Shewmr4_2477)
Accession : YP_734605.1
Strain : Shewanella sp. MR-4
Genome accession: NC_008321
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 2944868 - 2946061 bp
Length : 1194 bp
Strand : -
Note : KEGG: son:SO1812 methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase

DNA sequence :
ATGCAAGATGAATCAAGCAAGCAGTGGAAAGCCGCAACCCAAGCCATTCATGCCGGGCATGAGCGCGAAGCCTTTGGTAC
TTTGGTGACGCCACTTTATCAAACGGCGACCTTTGTCTTTGAGTCGGCGCAGCAAGGTGGTGAGCGATTCGCTGGCAACG
AACCCGGTTATATTTATACTCGCCTAGGTAACCCGACAGTTGCCGAGCTGGAACGTAAAATGGCGATTTTAGAAGGGGCA
GAAGCGGCGGCAGCAACGGCTTCTGGCATGGGGGCCGTATCGGCGGCGCTGTTGGCTAACCTCCAGATGGGCGATCATTT
AGTGGCTTCCAATGCGGTTTATGGCTGCACCTTCGCCCTTATGACCAGCCAATTTGCCCGCTTCGGTATCGAAGTCACCT
TAGTCGATTTTACCGATTTAGCGGCCATTGAGCGGGCCATCAAAGCCAACACTCGGGTGATTTTTTGCGAAACTCCGGTT
AATCCTCATTTACAGGTGTTTGATCTCAAAGGTATCGCCGATATTGCGAAACGGCATCAGCTTGTCAGCATTGTCGATAA
TACTTTTATGACGCCGCTGCTGCAGCAACCCTTGGCATTCGGTATCGATTTAGTGGTACACAGTGCGACTAAGTATTTGA
ATGGACACGGCGATGTAATTGCCGGCGTCGTGTGTGGCAGTGAAGAGCAGCTGCACAGAGTGAAATATGAAATCCTAAAA
GATATCGGCGCCGTCATGTCTCCCCACGATGCTTGGCTGATTTTGCGCGGGCTGAAAACCTTAGATGTGCGTTTGCAGCG
CCATTGTGACAGTGCCCAGCGTGTTGCCGAGTTTTTGGAGCAACATCCTGCTGTGACTCGGGTGTATTATCCAGGGCTTA
AATCTCATTCAGGGCACCGATTTATTGGTGGACAGATGGCGAGAGCTGGTGGCGTGATTGCCTTTGAGTTAGCCGCCTCT
CTTGAGCAAGCCATGGCTTTTGTGGGTTACCTTAAGCTGTTTTCAATCGCTGTAAGTTTGGGGGATGCGGAATCCCTTAT
TCAGCACCCAGCTTCCATGACCCATTCGCCCTACACGCCAGAGGCTCGCCAAGCCGCGGGGATAAGTGATAATTTACTGC
GGATCTCAATCGGTTTAGAGGATTGTGACGATATCATCGAGGATTTAAACCAAGCCTTGGCCATGCTGGCATAA

Protein sequence :
MQDESSKQWKAATQAIHAGHEREAFGTLVTPLYQTATFVFESAQQGGERFAGNEPGYIYTRLGNPTVAELERKMAILEGA
EAAAATASGMGAVSAALLANLQMGDHLVASNAVYGCTFALMTSQFARFGIEVTLVDFTDLAAIERAIKANTRVIFCETPV
NPHLQVFDLKGIADIAKRHQLVSIVDNTFMTPLLQQPLAFGIDLVVHSATKYLNGHGDVIAGVVCGSEEQLHRVKYEILK
DIGAVMSPHDAWLILRGLKTLDVRLQRHCDSAQRVAEFLEQHPAVTRVYYPGLKSHSGHRFIGGQMARAGGVIAFELAAS
LEQAMAFVGYLKLFSIAVSLGDAESLIQHPASMTHSPYTPEARQAAGISDNLLRISIGLEDCDDIIEDLNQALAMLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-56 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-63 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-64 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shewmr4_2477 YP_734605.1 methionine gamma-lyase BAC0207 Protein 8e-82 52