Gene Information

Name : leuS (Shewmr4_0997)
Accession : YP_733134.1
Strain : Shewanella sp. MR-4
Genome accession: NC_008321
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1162875 - 1165454 bp
Length : 2580 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATATAATCCCTCAGAAATTGAAGCCTTAGTGCAAAAGCACTGGCACGACAACAAAACCTTTGAAGTTAC
TGAAGATGCGAACAAAGAAAAGTTTTATTGCCTTTCGATGTTCCCCTATCCTTCAGGTCGACTCCACATGGGACACGTTC
GCAACTATACCATAGGCGATGTGGTTGCCCGCTTCCAGCGTCTTCAAGGCAAAAACGTGCTACAACCTATCGGTTGGGAC
TCTTTCGGTTTGCCTGCAGAAAACGCCGCAATCAACAACAAAACAGCCCCAGCACCATGGACTTATCAAAATATTGAGTA
CATGAAGAATCAGCTAAAACTGTTAGGTTTTGGCTATGACTGGAGCCGTGAAATCGCCACTTGTACCCCAGAATACTACC
GCTGGGAACAATGGTTCTTCACTAAACTTTACGAAAAAGGCTTAGTTTACAAGAAAACAGCCTCTGTTAACTGGTGCCCT
AACGATGAAACCGTACTGGCCAACGAGCAGGTACAAGACGGTTGCTGCTGGCGTTGTGATACCCCTGTAGAACAAAAAGA
AATTCCACAGTGGTTCATTAAGATCACCGCCTACGCCGAAGAACTGTTAAACGATATCGACACCTTAGACGGCTGGCCTG
AGCAAGTTAAGACCATGCAGCGCAACTGGATTGGTCGCAGCGAAGGCGTTGAGATGACCTTCGGTGTGGCAGGTAGCGAC
AAGTCATTCGATATCTACACAACCCGTCCCGATACCCTGATGGGCGTAACCTATGTGGCGATTGCTGCGGGTCATCCATT
AGCTGAATTAGCCGCTCAAACTAACCCTGAGCTGGCTCAATTTATTGAAGAGTGCAAAAACAGCACCACTTCAGAAGCCG
ATTTAGCCACCATGGAAAAACGCGGTGTCGCGACTGGTCTTTATGCGATTCACCCCATCACAGGCAAACAAGTGCCTATT
TGGGCGGCGAACTTTGTACTGATGAACTACGGCACTGGTGCCGTGATGTCAGTCCCTGGCCACGACCAACGCGATTACGA
ATTTGCTAAAAAGTACAATCTGTCCATCGAAGCGGTAATCAAGCCTGTTGATGGCGAGTTAGACATCAGCGAAGCGGCTT
ACACCGAAAAAGGCGTACTGTTTAACTCTGGCGAGTTCGACGGTTTAGACTTTGACGGCGCCTTCAATGCCATCGCCGAC
AAGTTAGTGGCTGAAGGTAAAGGCAAACGCCAAGTAAACTACCGTCTACGCGACTGGGGTGTATCACGTCAACGTTACTG
GGGCGCACCGATTCCTATGGTGACCTTAGCCGACGGCACTGTTATTCCTACGCCTGAAGATCAACTGCCAGTGATTCTGC
CAGAAGATGTGGTGATGGATGGTATTCAAAGCCCAATCAAGGCTGATAAAGAGTGGGCGAAAACCCAAGTTAACGGCCAA
GATGCGCTACGCGAAACCGATACCTTCGATACCTTTATGGAGTCTTCTTGGTATTACGCCCGTTACTGCAGCCCACAAGC
AGACCAAATGTTAGATCCAACCAAGGCTAACTACTGGTTACCCGTGGATCAGTATATTGGTGGTATCGAACACGCTTGTA
TGCACTTGTTATACTTCCGCTTCTTCCACAAGTTGCTGCGTGATGCGGGTCTGGTTAACTCTAACGAGCCAGCGAAACAA
CTGCTGACTCAGGGCATGGTTTTAGCCGATGCCTTCTACTACAACAACGACAAAGGTGCCCGTGTATGGGTGTCTCCGCT
GGATGTAGTGACCACAGAAAAAGACGACAAGGGCCGAGTCACCAAAGCCATCGATAAAGACGGTAACGAACTGGTTTACA
CCGGTATGTGCAAGATGTCTAAGTCGAAAAACAACGGTATCGACCCACAGGTGATGGTAGAGAAATACGGTGCCGACACA
GTGCGTCTGTTTATGATGTTCGCATCACCACCAGAATTAACGCTGGAATGGCAAGAGTCAGGCGTTGAAGGCGCACACCG
CTTTATCAAACGTCTGTGGAAACTGGCCAGCGATTATGTGGCGCAGGACAACAGTGAAGCCTTAGACGTTAGCAAATTAA
CTAGCGAGCAAAAAGCGCTGCGCCGTGAAGTGCACAAGACCATCGCTAAGGTGACCGATGATATCGGCCGTCGTCAGATG
TTCAACACTGCGGTTGCCGCCGTGATGGAACTGATGAACCACCTGCAAAAAGCGCCACAAACCACAGGTCAAGACCGAGC
CATTATCGGTGAAGCTTTAACTGCGGTAGTGCGTTTACTGTACCCAATCATCCCACACGTGAGCTTCACCCTGTGGAACG
AACTGGGCAACACCAACAGCATCGAAGACAGCCAATGGCCTGTTGTGGATGAATCTGCACTGGTAGAAGACAGCAAACTC
ATCGTGGTACAAGTGAACGGTAAAGTGCGCGCTAAAATCACTGTCGCTGCCGATGCTGACCAAGCGTCTGTTGAGGCTCT
GGGTATGGCGGACGAGCAAGTCATCAAGTACTTAGATGGTGTTACGGTTCGTAAAGTTATCTATGTACCCGGTAAACTGC
TCAGCATCGTTGCCAACTAA

Protein sequence :
MQEQYNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARFQRLQGKNVLQPIGWD
SFGLPAENAAINNKTAPAPWTYQNIEYMKNQLKLLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCP
NDETVLANEQVQDGCCWRCDTPVEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGSD
KSFDIYTTRPDTLMGVTYVAIAAGHPLAELAAQTNPELAQFIEECKNSTTSEADLATMEKRGVATGLYAIHPITGKQVPI
WAANFVLMNYGTGAVMSVPGHDQRDYEFAKKYNLSIEAVIKPVDGELDISEAAYTEKGVLFNSGEFDGLDFDGAFNAIAD
KLVAEGKGKRQVNYRLRDWGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVILPEDVVMDGIQSPIKADKEWAKTQVNGQ
DALRETDTFDTFMESSWYYARYCSPQADQMLDPTKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLRDAGLVNSNEPAKQ
LLTQGMVLADAFYYNNDKGARVWVSPLDVVTTEKDDKGRVTKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADT
VRLFMMFASPPELTLEWQESGVEGAHRFIKRLWKLASDYVAQDNSEALDVSKLTSEQKALRREVHKTIAKVTDDIGRRQM
FNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALTAVVRLLYPIIPHVSFTLWNELGNTNSIEDSQWPVVDESALVEDSKL
IVVQVNGKVRAKITVAADADQASVEALGMADEQVIKYLDGVTVRKVIYVPGKLLSIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-162 43