Gene Information

Name : guaA (sync_0047)
Accession : YP_729285.1
Strain : Synechococcus sp. CC9311
Genome accession: NC_008319
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 48046 - 49632 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCATCAGTCCAGAGCGAAGGTCAGCGCAAACCGGCCATCGTCATTCTTGATTTCGGTTCCCAGTACTCGGAACTGAT
TGCACGCCGCGTTCGTGAGACGGAGGTGTTTTCGGTGGTGTTGGGCTACAGCACCAGCGCTGAAGAATTACGGGCCTTGG
CTCCGCGTGGAATCATCCTCAGCGGAGGCCCAAGTTCGGTTTATGCCGATGAGGCTCCCCTCTGCGATCCAGCGATTTGG
GATCTGGGCGTCCCTGTGCTGGGGGTCTGCTACGGCATGCAGTTGATGGTTCAGCAGCTTGGTGGTCAGGTGGTCGCGGC
TACGGGTAAGGCTGAATACGGCAAGGCTCCGCTCAAGGTGGATGACCCCACTGCACTTCTCACGAATGTTGAGAGTGGCT
CCACGATGTGGATGAGTCACGGTGATTCCGTGGAGGCTTTGCCCGACGGCTTCCTGCGTTTGGCTCATACAGCGAATACG
CCTGAGGCGGCTATCGCGAATCACAAGCGACGCTTATACGGCGTTCAATTTCACCCTGAGGTGGTTCATTCCACTGGTGG
AATGGTGATGATTCGCAATTTTGTGTATCACATCTGTGGTTGTGAACCGGATTGGACCACTGAGGCTTTTATCGATGAAG
CAGTGGCAAATGTGCGTGATCAAGTTGGTCAAAAGAGAGTGCTGCTTGCTCTCTCAGGAGGCGTGGATTCTTCAACCCTT
GCTTTTTTATTGAAGAAAGCGATTGGAGATCAACTTACCTGCATGTTTATTGATCAAGGCTTCATGCGTAAAGGCGAACC
TGAATTCCTGATGGAGTTCTTTGATCGTAAATTTAATATTCATGTTGAGTATATCAATGCTCGTGAACGGTTTATCAAAA
AGCTTGATGGCATTACGGATCCAGAAGAGAAGCGCAAAATCATTGGCACGGAATTCATCCGTGTGTTTGAAGAAGAGAGT
CGCCGTCTAGGCCCATTTGATTATTTAGTCCAGGGCACGCTTTATCCGGATGTGATTGAAAGTGCTGGCACCAACGTGGA
TCCCAAAACCGGGGAGCGTGTGGCTGTGAAGATCAAGAGCCATCACAACGTGGGAGGTCTTCCTAAGGATCTGCGCTTCA
AGTTGGTGGAGCCCCTACGCAAGCTGTTTAAGGATGAAGTTCGTAAGGTTGGTCGAACGCTTGGGTTGCCCGAGGAGATC
GTGAGTCGCCATCCATTCCCAGGCCCTGGACTAGCGATTCGCATCTTGGGCGAAGTCACGGAGGAAAAGCTCGATTGTTT
GCGTGATGCAGATCTGATTGTGCGCGAGGAAGTGAACGCAGCGGGGCTCTATCACGACATTTGGCAGGCGTTTGCGGTGC
TTCTTCCCGTGCGCTCAGTGGGTGTGATGGGTGATAAGCGCACTTATGCCTGGCCGATCGTGCTGCGCTGTGTATCGAGT
GAGGACGGCATGACCGCTGATTGGTCGAGGCTTCCTTATGACCTTATGGAAGTGATTTCCAATCGGATTGTGAATGAGGT
GAAAGGAGTGAATCGCGTGGTAATGGACATCACTAGCAAGCCTCCAGGAACGATTGAGTGGGAATAG

Protein sequence :
MSSVQSEGQRKPAIVILDFGSQYSELIARRVRETEVFSVVLGYSTSAEELRALAPRGIILSGGPSSVYADEAPLCDPAIW
DLGVPVLGVCYGMQLMVQQLGGQVVAATGKAEYGKAPLKVDDPTALLTNVESGSTMWMSHGDSVEALPDGFLRLAHTANT
PEAAIANHKRRLYGVQFHPEVVHSTGGMVMIRNFVYHICGCEPDWTTEAFIDEAVANVRDQVGQKRVLLALSGGVDSSTL
AFLLKKAIGDQLTCMFIDQGFMRKGEPEFLMEFFDRKFNIHVEYINARERFIKKLDGITDPEEKRKIIGTEFIRVFEEES
RRLGPFDYLVQGTLYPDVIESAGTNVDPKTGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRKVGRTLGLPEEI
VSRHPFPGPGLAIRILGEVTEEKLDCLRDADLIVREEVNAAGLYHDIWQAFAVLLPVRSVGVMGDKRTYAWPIVLRCVSS
EDGMTADWSRLPYDLMEVISNRIVNEVKGVNRVVMDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-129 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-131 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-132 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-132 54