Gene Information

Name : lysS (sync_0116)
Accession : YP_729353.1
Strain : Synechococcus sp. CC9311
Genome accession: NC_008319
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 123701 - 125170 bp
Length : 1470 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGTCTGAACTTCGTGAGACCCGCTTGGAGAAGGCGAATGCTCTCAAAGAACAGGGGCAAGAGCCGTATGCATTGCGTTT
TGATCTCACCGATCGCATGGCTCGCCTGCAAGCCGATCACGCTGATCTTGCAAAAGGCGCCGAGCGAGACCTCAAAGTTT
CGGTTGCTGGTCGGGTGATGACGCGCCGGGTGATGGGCAAGCTTGCATTTTTCACGCTGGCGGATGAAACGGGAACGATC
CAGTTGTTCCTTGAGAAAGCAACGCTGGGCGACAGCTTTGCTCAGCTCAGTTCCTTGGTGGATGCAGGTGACCTCATCGG
GGTTCATGGCATCTTGCGCCGCACCGATCGGGGTGAGTTGTCCGTCAAGGTGAGCAAATGGGAGATGCTCACCAAATCGC
TGCAGCCGTTGCCAGATAAGTGGCATGGCCTGGCGGATGTGGAGAAGCGCTATCGACAGCGCTATCTGGATTTGATCGTG
ACGCCGCAGTCCCGTGAGACGTTCCGGCGTCGGGCGATGGCTGTTAGTGCGATCCGCCGTTGGTTGGATGAACGCGACTT
TCTAGAGATCGAAACACCGGTCCTGCAGTCCGAAGCCGGTGGCGCTGAGGCGCGGCCGTTCATCACGCATCACAACACCC
TCGATCTGCCTCTCTACTTGCGGATTGCCACTGAGCTCCATCTCAAACGGCTCGTGGTGGGTGGATTTGAACGGGTCTAT
GAGCTCGGGCGGATCTTTCGCAACGAAGGGGTGAGCACGCGCCATAACCCTGAATTCACTTCGGTGGAGGTGTATCAGGC
CTATGCCGATTACAACGACATGATGACGCTCACCGAACAGCTAATCGCTTCGGTTTGTGAGCAGGTATGCGGTACAACCC
GCATCAGCTACCAGGGCGTGGAGGTGGACCTGACGCCGTCCTGGAGACGCGCCACGATGCATGAACTCGTGCAGGAGGCC
ACCGGCCTGGATTTCACCTCCTTCGAGACCCGTGAAGCGGCTGTGGAGGCGATGCGAGCGGCCAATCTCCCGGCGCCAGA
TAAGGCCGACACCGTTGGACGGCTTTTGAACGAAGCGTTTGAGCATGCTGTGGAACCCAATTTGATCCAGCCCACCTTTG
TGCTCGATTACCCGCAGGAAATTTCACCCCTGGCGCGTAAACATCGCAGCAAGCCAGGGCTTGTGGAGCGCTTTGAATTG
TTCATCGTGGGCCGAGAAACGGCCAATGCCTTCAGTGAGCTCACGGATCCTTTGGATCAAAGAGGCCGCATGGAGCTCCA
GCAGGAACGTCGTGCTGCCGGAGATGTGGAAGCCAGCGGAGTGGATGAAGATTTCATCCAGGCGCTCGAAGTGGGAATGC
CCCCCACGGGTGGACTTGGAATCGGCATTGATCGCCTGGTGATGCTGCTTACTGACAGCCCCTCGATTCGGGATGTCATT
GCCTTCCCATTGATGCGACCTGAGGGGTGA

Protein sequence :
MSELRETRLEKANALKEQGQEPYALRFDLTDRMARLQADHADLAKGAERDLKVSVAGRVMTRRVMGKLAFFTLADETGTI
QLFLEKATLGDSFAQLSSLVDAGDLIGVHGILRRTDRGELSVKVSKWEMLTKSLQPLPDKWHGLADVEKRYRQRYLDLIV
TPQSRETFRRRAMAVSAIRRWLDERDFLEIETPVLQSEAGGAEARPFITHHNTLDLPLYLRIATELHLKRLVVGGFERVY
ELGRIFRNEGVSTRHNPEFTSVEVYQAYADYNDMMTLTEQLIASVCEQVCGTTRISYQGVEVDLTPSWRRATMHELVQEA
TGLDFTSFETREAAVEAMRAANLPAPDKADTVGRLLNEAFEHAVEPNLIQPTFVLDYPQEISPLARKHRSKPGLVERFEL
FIVGRETANAFSELTDPLDQRGRMELQQERRAAGDVEASGVDEDFIQALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVI
AFPLMRPEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-103 51
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-84 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_729353.1 lysyl-tRNA synthetase VFG1668 Protein 6e-104 51