Gene Information

Name : murD (H16_A3275)
Accession : YP_727717.1
Strain :
Genome accession: NC_008313
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 3540683 - 3542194 bp
Length : 1512 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
GTGTTTGGCGAGCTGCAAAAACCTCATGTGCTGGTACTGGGCCTTGGTGAGTCGGGCCTGGCCATGGCGCGCTGGTGTGG
CCTGAACGGCTGCGCGGTGCGCGTGGCTGACACGCGCGAGGCGCCCGCCAACCTTGTCTTCCTGCAGGCCGAGCTGACTT
CGGCCGAATTCGTCGGCGGCCCGTTCGCCGACAGCCTGCTCGACGGCATCGGCCTGGTGGCGATCAGTCCGGGCCTGTCG
CCGCTGGAAGCCGCCACTGGCGCGCTGCTGGCCGCGGCGCAGGCGCGCGGCATCCCCGTGTGGGGCGAGATCGAGCTGTT
CGTGCGCGCGCTGCGCCACCTGGAAGCCGAGTCCGGCTACGCGCCGAAGATCCTGGCGATCACCGGCACCAACGGCAAGA
CCACCACCACCGCGCTGACCGGCCGGCTGGTGGAGCGCGCCGGCAAGAGCGTGGCGGTGGCGGGCAATATCAGCCCGTCG
GCGCTGGACAAGCTGTCGGCCTGCATCGCCTCGGCATCGCTGCCGGAGGTGTGGGTGCTTGAGCTGTCCAGCTTCCAGCT
GGAAACCACGCACACGCTGGCGCCCGCCGCGGCGACTGTGCTCAACGTCACCCAGGACCACCTGGACTGGCATGGCTCGA
TGGAAGCCTATGCCGCGTCCAAGGCGCGCATCTTCGGGCCGGCCGGCAGCGAGTGCGTGCAGGTGCTCAACCGCAACGAC
CGCCTGACCATGGATATGGCGCGGCCCGGGAGCACGCCGCTGACCTTTGGCACCGACCTGCCGGAAACGCCGGGCAGCTT
CGGCATCCTGCGCGAGGGCGGCATGCCCTGGCTGGTGCTGGCCGAACCCGATCCGGACGCGGAAGGGGAGGGCAAGCCGC
GCCGCCGCAAGGCCGCCGAGGTGGCCCGGGAAGCCGTGCCGGTGCGCCACAAGCGCCTGATGCCGGCCGACGCGCTGCAT
ATCCGCGGCATGCACAACGCCACCAACGCGATGGCCGCGCTGGCGCTGTGCCGCGCCATCGACCTGCCGATGAACGCACT
GCTGCACGGCCTGCGCGAATACCGCGGCGAGCCGCACCGCGTGGAGTGGGTTGCGACCATCGACGATGTCGAGTATTTCG
ACGACAGCAAGGGCACCAACGTGGGCGCAACCGTGGCCGCGCTGTCTGGGCTGGACAAGCGCGTGGTGCTGATCGCCGGC
GGCGAAGGCAAGGGCCAGGATTTCTCGCCGCTGGCCGCGCCGGTGGCGCAGTACGCGCGCGCGGTGGTGCTGATCGGCCG
TGCCGCGGGTGAACTGCGCGATGCATTGCAGGGCAGCGGTGCCAGCCTGGTCGACGCCGGCACGCTGGAAGAGGCCGTGA
CCAAGGCTGCCGGACTGGCCGAGAGCGGCGATGTGGTGCTGCTGTCGCCGGCATGCGCCAGCCTCGACATGTTCCGCAAC
TACGTGCATCGCGCCGAGGTGTTCCGCGGCGCCGTGGAAGAACTGGCGCTGTCCCGGGGGATCCTGCCATGA

Protein sequence :
MFGELQKPHVLVLGLGESGLAMARWCGLNGCAVRVADTREAPANLVFLQAELTSAEFVGGPFADSLLDGIGLVAISPGLS
PLEAATGALLAAAQARGIPVWGEIELFVRALRHLEAESGYAPKILAITGTNGKTTTTALTGRLVERAGKSVAVAGNISPS
ALDKLSACIASASLPEVWVLELSSFQLETTHTLAPAAATVLNVTQDHLDWHGSMEAYAASKARIFGPAGSECVQVLNRND
RLTMDMARPGSTPLTFGTDLPETPGSFGILREGGMPWLVLAEPDPDAEGEGKPRRRKAAEVAREAVPVRHKRLMPADALH
IRGMHNATNAMAALALCRAIDLPMNALLHGLREYRGEPHRVEWVATIDDVEYFDDSKGTNVGATVAALSGLDKRVVLIAG
GEGKGQDFSPLAAPVAQYARAVVLIGRAAGELRDALQGSGASLVDAGTLEEAVTKAAGLAESGDVVLLSPACASLDMFRN
YVHRAEVFRGAVEELALSRGILP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 4e-59 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 4e-59 41