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Name : lysS (H16_A1167) Accession : YP_725676.1 Strain : Genome accession: NC_008313 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 1267105 - 1268649 bp Length : 1545 bp Strand : - Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGACTGAACCGAACCGCGCCCAGGCCAAGCCAGCCGCCGCAGATACTCCCGCCGTCGACGAGAACAAGATCATCGCGGA GCGGCGCGAGAAACTGGCCGCGCTGCGCCAGCAAGGCGTGCCCTTCCCCAACGATTTCCGCCCCACCCACCAGGCCGCCG CGCTGCAGGCGCAATACACCGAGACCGAGCAGGCCACGCTCGAGGCCGCGCCGGTCGAGGTCGCCATCGCCGGGCGCATG ATGCTCAAGCGCGTGATGGGCAAGGCCAGCTTTGCCACGGTGCAGGACGGCAGCGGCCAGATCCAGTTCTACATCACCCG CGACAAGGTCGGCGAAGAGGTCTACGCGGCCTTCAAGCACTGGGACCTGGGCGACATCATCAGCGCCCGCGGCGAACTGT TCCGCACCAACAAGGGCGAGCTGTCGGTGCAGGTGCGCGAGCTGCGCCTGCTGTCCAAGTCGCTGCGTCCGCTGCCGGAC AAGTTCCACGGCCTGGCCGACCAGGAAATGAAGTACCGCCAGCGCTATGTCGACCTGATCGTGTCGCCGGAAACACGCAA CACCTTCCGCGCCCGCACCAATGCGATCTCGTCGCTGCGCCGCCATATGGCCGATGCCGGCTTCATGGAAGTGGAAACGC CGATGCTGCACCCGATCCCGGGCGGCGCCGCGGCCAAGCCCTTCATCACGCACCACAATGCGCTGGACATGCAGATGTTC ATGCGCATCGCGCCCGAGCTGTACCTGAAGCGCCTGATCGTCGGCGGCTTCGAGCGTGTGTTCGAGATCAACCGCAACTT CCGCAACGAAGGGGTGAGCCCGCGCCACAACCCCGAGTTCACCATGATGGAGTTCTACGCGGCCTACACGGACTACCGCT GGCTGATGGACTTCACCGAGGACCTGATCCGCAAGGCCGCGATCGATGCGCGCGGCAGTGCCGTGCTGACCTACCAGGAC CGCGAGCTGGACCTGTCCAAGCCGTTCCATCGGCTGACGATCTGCCAGGCGATCCAGAAGTTCGCACCGCAGTACACCGA TGCGCAACTGGCCGATGCCGGGTTCCTGCGCACCGAGCTGAAGAAGTTCGGCGTCAACACCAACGCGCCGCAGTTCCTCA ACGCCGGCCTGGGCACGCTGCAACTGGTGCTGTTCGAGGAAACCGCGGAAAACCAGCTGTGGGAGCCGACCTTCATCGTC GACTACCCGGTCGAGGTCTCGCCGCTGGCACGCGCCTCGGACACGGTGCCTGGCATCACCGAGCGCTTTGAACTGTTCAT CACCGGCCGCGAGATCGCCAACGGCTTCTCGGAGCTGAACGATGCCGAGGACCAGGCCGACCGTTTCCGCAAGCAGGTCG AGCAGAAGGACGCCGGCGATGAAGAAGCCATGTACTTCGACGCCGACTACATCCGCGCGCTGGAATACGGCATGCCCCCG ACGGGCGGCTGCGGCATCGGCATCGACCGCCTGGTGATGCTGCTGACGGATAGCCCGAATATCCGCGACGTCATCCTGTT CCCGCACCTGCGCCGGGAAGACTGA Protein sequence : MTEPNRAQAKPAAADTPAVDENKIIAERREKLAALRQQGVPFPNDFRPTHQAAALQAQYTETEQATLEAAPVEVAIAGRM MLKRVMGKASFATVQDGSGQIQFYITRDKVGEEVYAAFKHWDLGDIISARGELFRTNKGELSVQVRELRLLSKSLRPLPD KFHGLADQEMKYRQRYVDLIVSPETRNTFRARTNAISSLRRHMADAGFMEVETPMLHPIPGGAAAKPFITHHNALDMQMF MRIAPELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEDLIRKAAIDARGSAVLTYQD RELDLSKPFHRLTICQAIQKFAPQYTDAQLADAGFLRTELKKFGVNTNAPQFLNAGLGTLQLVLFEETAENQLWEPTFIV DYPVEVSPLARASDTVPGITERFELFITGREIANGFSELNDAEDQADRFRKQVEQKDAGDEEAMYFDADYIRALEYGMPP TGGCGIGIDRLVMLLTDSPNIRDVILFPHLRRED |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 2e-127 | 56 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 5e-79 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_725676.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 1e-127 | 56 |
